PANTHER Gene Information

Gene Symbol(s):

hm:zeh0659

Organism:

Danio rerio

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Gene Name:

5,6-dihydroxyindole-2-carboxylic acid oxidase precursor

Gene ID:

ZDB-GENE-040718-249

Protein ID:

Q6DGE4

Persistent Id:

PTN000158649

Alternate Ids:

Q6DGE4(Synonym)	BC076406(EMBL)
NP_001002749(refSeq)	57526500(GI)
ENSDARP00000073055(Ensembl_PRO)	ENSDART00000078594(Ensembl_TRS)
AAH76406(EMBL-CDS)	437022(GeneID)
Q6DGE4_DANRE(UniProtKB-ID)	ENSDARG00000056151(Ensembl)
ZDB-GENE-040718-249(ZFIN)
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PANTHER Classification

PANTHER Family:	TYROSINASE FAMILY MEMBER (PTHR11474)
PANTHER Subfamily:	5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACID OXIDASE (PTHR11474:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	melanosome organization melanocyte differentiation
PANTHER GO-slim Cellular Component:	melanosome
PANTHER protein class:	oxygenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	oxidoreductase activity, metal ion binding
GO BP Complete:	melanin biosynthetic process, developmental pigmentation, response to thyroid hormone, melanocyte differentiation, melanosome organization, retinal pigment epithelium development, pigmentation
GO CC Complete:	melanosome membrane, melanosome, membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of amino acids and derivatives, Melanin biosynthesis, Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12450\|UniProtKB=P17643	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020774.7\|UniProtKB=A0A2J8M4Q3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016261.3\|UniProtKB=G3RJH0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000062815.1\|UniProtKB=A0A5F8A188	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98881\|UniProtKB=P07147	Mus musculus	LDO
RAT\|RGD=1593266\|UniProtKB=D3ZH71	Rattus norvegicus	LDO
BOVIN\|Gene=TYRP1\|UniProtKB=Q8WN57	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000020985.6\|UniProtKB=F1MBG9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005193.5\|UniProtKB=F6Q7U8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009440.4\|UniProtKB=F7BQT4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000019011.5\|UniProtKB=M3WPS0	Felis catus	O
FELCA\|Gene=TYRP1\|UniProtKB=Q2VPW6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008780.1\|UniProtKB=A0A8I3N097	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000015054.4\|UniProtKB=F7FUN5	Monodelphis domestica	LDO
CHICK\|Gene=TYRP1\|UniProtKB=O57405	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010014092.1\|UniProtKB=F1NXQ4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011322.4\|UniProtKB=G1KL56	Anolis carolinensis	LDO
XENLA\|Gene=tyrp1.S\|UniProtKB=A0A1L8HNZ5	Xenopus laevis	O
XENLA\|Gene=tyrp1.L\|UniProtKB=Q7ZYE8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1001464\|UniProtKB=Q28HG0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004326.2\|UniProtKB=H2LHF8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004723.2\|UniProtKB=A0A3B3HNW7	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000013264.1\|UniProtKB=W5N6U1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009054.3\|UniProtKB=F6R2I4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005005.3\|UniProtKB=F6WL94	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004871.3\|UniProtKB=F6SPL0	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009351.3\|UniProtKB=F6XL13	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118407975\|UniProtKB=A0A9J7HVW6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431962\|UniProtKB=A0A9J7ME91	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431963\|UniProtKB=A0A9J7MH66	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00015332\|UniProtKB=P34269	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG12272\|UniProtKB=A8XF53	Caenorhabditis briggsae	LDO
CAEBR\|Gene_ORFName=CBG12271\|UniProtKB=A8XF52	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090499\|UniProtKB=A0A2A6BQG6	Pristionchus pacificus	LDO
CAEEL\|WormBase=WBGene00009001\|UniProtKB=Q19673	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00040579\|UniProtKB=A8Y191	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00016419\|UniProtKB=O01497	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04025\|UniProtKB=A8WW09	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00115223\|UniProtKB=A0A2A6C0P8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277892\|UniProtKB=A0A2A6B3L8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101791\|UniProtKB=A0A2A6C3B5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278986\|UniProtKB=A0A2A6C452	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00107503\|UniProtKB=A0A8R1YHA7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00021553\|UniProtKB=O76708	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035349\|UniProtKB=A8XL54	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00105089\|UniProtKB=A0A2A6CJW1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091242\|UniProtKB=A0A2A6BT42	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00022231\|UniProtKB=Q95XC6	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG05433\|UniProtKB=A8WZV4	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00010661\|UniProtKB=Q9XUS8	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037728\|UniProtKB=A8XSB6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00114146\|UniProtKB=A0A2A6BIE1	Pristionchus pacificus	O
HELRO\|EnsemblGenome=HelroG168144\|UniProtKB=T1F079	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203224\|UniProtKB=A7RWK6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216737\|UniProtKB=A7SSF6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198393\|UniProtKB=A7RKE4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203775\|UniProtKB=A7RXW5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240046\|UniProtKB=A7RQY2	Nematostella vectensis	LDO
EMENI\|EnsemblGenome=ANIA_01318\|UniProtKB=Q5BDR2	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_00231\|UniProtKB=Q5BGU9	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_10821\|UniProtKB=C8V037	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07912\|UniProtKB=Q5AUW8	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_05311\|UniProtKB=Q5B2B9	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G01070\|UniProtKB=Q4WFT7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU10865\|UniProtKB=A7UWM5	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU09199\|UniProtKB=V5IPR9	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_13698\|UniProtKB=Q0U3G6	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04287\|UniProtKB=Q0UVC7	Phaeosphaeria nodorum	O
PHANO\|Gene_ORFName=SNOG_13474\|UniProtKB=Q0U440	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU11382\|UniProtKB=A7UX66	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_01119\|UniProtKB=Q0V4E5	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_03559\|UniProtKB=Q0UXF5	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09849\|UniProtKB=Q0UEG5	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_14370\|UniProtKB=Q0U1I9	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04568\|UniProtKB=Q0UUJ6	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_02799\|UniProtKB=Q5B9I1	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_09388\|UniProtKB=Q5AQP2	Emericella nidulans	LDO
NEUCR\|EnsemblGenome=NCU05762\|UniProtKB=Q7S4R1	Neurospora crassa	O
PHANO\|Gene_ORFName=SNOG_12540\|UniProtKB=Q0U6S4	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU10031\|UniProtKB=Q7S0E7	Neurospora crassa	LDO
PHANO\|Gene_ORFName=SNOG_04173\|UniProtKB=Q0UVP1	Phaeosphaeria nodorum	O
PHANO\|Gene_ORFName=SNOG_15093\|UniProtKB=Q0TZT9	Phaeosphaeria nodorum	LDO
USTMA\|EnsemblGenome=UMAG_10756\|UniProtKB=A0A0D1CHR5	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_01130\|UniProtKB=A0A0D1E6L1	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_13399\|UniProtKB=E3KSA5	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_17780\|UniProtKB=E3L5F5	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11024\|UniProtKB=E3KN59	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_91772\|UniProtKB=F4PBI8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_12457\|UniProtKB=F4P661	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_86168\|UniProtKB=F4NVT9	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_36317\|UniProtKB=F4PFF7	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_88732\|UniProtKB=F4P2Z0	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_7226\|UniProtKB=F4PG32	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_86650\|UniProtKB=F4NWE6	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_89622\|UniProtKB=F4P663	Batrachochytrium dendrobatidis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_90660\|UniProtKB=F4P7Q7	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_27677\|UniProtKB=F4PBL1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_89716\|UniProtKB=F4P662	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_25580\|UniProtKB=F4P543	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0283653\|UniProtKB=Q54QT0	Dictyostelium discoideum	LDO
DICDI\|dictyBase=DDB_G0283651\|UniProtKB=Q54QT1	Dictyostelium discoideum	O
PHYRM\|Gene=H3HCH2_PHYRM\|UniProtKB=H3HCH2	Phytophthora ramorum	O
PHYRM\|Gene=H3GI94_PHYRM\|UniProtKB=H3GI94	Phytophthora ramorum	O
PHYRM\|Gene=H3GR62_PHYRM\|UniProtKB=H3GR62	Phytophthora ramorum	O
PHYRM\|Gene=H3GPM4_PHYRM\|UniProtKB=H3GPM4	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GI93_PHYRM\|UniProtKB=H3GI93	Phytophthora ramorum	O
PHYRM\|Gene=H3GPM3_PHYRM\|UniProtKB=H3GPM3	Phytophthora ramorum	O
PHYRM\|Gene=H3GPM1_PHYRM\|UniProtKB=H3GPM1	Phytophthora ramorum	O
PHYRM\|Gene=H3GCI8_PHYRM\|UniProtKB=H3GCI8	Phytophthora ramorum	O
PHYRM\|Gene=H3GEM4_PHYRM\|UniProtKB=H3GEM4	Phytophthora ramorum	O
PHYRM\|Gene=H3GFA6_PHYRM\|UniProtKB=H3GFA6	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GPM2_PHYRM\|UniProtKB=H3GPM2	Phytophthora ramorum	O
PHYRM\|Gene=H3GFA7_PHYRM\|UniProtKB=H3GFA7	Phytophthora ramorum	LDO