PANTHER Gene Information

Gene Symbol(s):

TBC1D3K

Organism:

Homo sapiens

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Gene Name:

TBC1 domain family member 3K

Gene ID:

HGNC:51245

Protein ID:

A0A087X1G2

Enhancers:

View enhancers for HUMAN|HGNC=51245|UniProtKB=A0A087X1G2

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002506288

Alternate Ids:

TBC3K_HUMAN(UniProtKB-ID)	612339349(GI)
XP_006722300(refSeq)	101060351(GeneID)
ENSP00000484181(Ensembl_PRO)	HGNC:51245(HGNC)
ENST00000620247(Ensembl_TRS)	TBC1D3K{ECO:0000312\|HGNC:HGNC:51245}(Symbol)
AC243569(EMBL)	TBC3K(Synonym)
ENSG00000273513(Ensembl)
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PANTHER Classification

PANTHER Family:	TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN (PTHR22957)
PANTHER Subfamily:	TBC1 DOMAIN FAMILY MEMBER 3-RELATED (PTHR22957:SF571)
PANTHER GO-slim Molecular Function:	GTPase activator activity
PANTHER GO-slim Biological Process:	activation of GTPase activity
PANTHER GO-slim Cellular Component:
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTPase activator activity
GO BP Complete:	-
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000008852.5\|UniProtKB=H2QBZ8	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000042164.2\|UniProtKB=H2RDE2	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000008885.6\|UniProtKB=A0A2I3TAN1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000039854.1\|UniProtKB=A0A2I2ZW86	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000032007.3\|UniProtKB=H9H5G0	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000047892.2\|UniProtKB=H9H5H4	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000063373.1\|UniProtKB=A0A5F7ZB12	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000049155.2\|UniProtKB=H9H5C6	Macaca mulatta	LDO
MACMU\|Ensembl=ENSMMUG00000042311.2\|UniProtKB=H9H410	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000046240.2\|UniProtKB=A0A1D5R8F2	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054601.1\|UniProtKB=A0A5F8A3S5	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000061685.1\|UniProtKB=A0A5F7ZW48	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000030260.3\|UniProtKB=F6Y7T7	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000057090.1\|UniProtKB=A0A5F7ZN08	Macaca mulatta	O
PIG\|Ensembl=ENSSSCG00005045661.1\|UniProtKB=A0A4X1SIQ0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000027943.3\|UniProtKB=A0A9L0TD20	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039660.3\|UniProtKB=A0A3Q2GVB8	Equus caballus	O
MONDO\|Ensembl=ENSMODG00000016585.4\|UniProtKB=H9H702	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050278.1\|UniProtKB=A0A6I8P7B6	Ornithorhynchus anatinus	O
DANRE\|ZFIN=ZDB-GENE-131121-469\|UniProtKB=E7EZ23	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004039.1\|UniProtKB=W5M8V9	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000027212.1\|UniProtKB=A0A3B3IEK9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-081104-56\|UniProtKB=F1R1B6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060503-323\|UniProtKB=A0A0R4IHT5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001862.1\|UniProtKB=W5M1A3	lepisosteus oculatus	O
BRAFL\|Gene=LOC118407550\|UniProtKB=A0A9J7HT07	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100894091\|UniProtKB=A0A7M7NZD0	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00012894\|UniProtKB=Q9U2D8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08089\|UniProtKB=E3CU00	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG07920\|UniProtKB=A8X569	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00114782\|UniProtKB=A0A2A6CJ99	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0020620\|UniProtKB=A1Z9K4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003341\|UniProtKB=F5HLQ8	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP003818\|UniProtKB=A0A1S4GJT7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006994\|UniProtKB=D7EJZ8	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_193121\|UniProtKB=E9G2V9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW010579\|UniProtKB=B7Q9D9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG194688\|UniProtKB=T1FWB6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG84860\|UniProtKB=T1G5P7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67442\|UniProtKB=T1FZ09	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g78932\|UniProtKB=A7RF34	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG13231\|UniProtKB=B3RSY1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_32573\|UniProtKB=A9V0E2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_22245\|UniProtKB=A9UQ02	Monosiga brevicollis	O
EMENI\|EnsemblGenome=ANIA_03094\|UniProtKB=Q5B8N6	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G12470\|UniProtKB=Q4WYB7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU10309\|UniProtKB=A7UW34	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_05701\|UniProtKB=A7EK55	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09629\|UniProtKB=Q0UF35	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC1778.09\|UniProtKB=Q9Y7J5	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE04290\|UniProtKB=Q5KGA6	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10406\|UniProtKB=A0A0D1CLW1	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_10400\|UniProtKB=E3KKV4	Puccinia graminis	O
YARLI\|EnsemblGenome=YALI0_F12573g\|UniProtKB=Q6C1X8	Yarrowia lipolytica	O
PHANO\|EnsemblGenome=SNOG_03466\|UniProtKB=Q0UXP8	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC23D3.03c\|UniProtKB=Q09844	Schizosaccharomyces pombe	O
YEAST\|SGD=S000004804\|UniProtKB=Q04322	Saccharomyces cerevisiae	O
YEAST\|SGD=S000006170\|UniProtKB=Q12344	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFL161C\|UniProtKB=Q755I4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000189285\|UniProtKB=A0A1D8PIQ7	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F18106g\|UniProtKB=Q6C199	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05407\|UniProtKB=Q5B223	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G13850\|UniProtKB=Q4WLE1	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06362\|UniProtKB=Q7S9U4	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01932\|UniProtKB=A7E9F2	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_14427\|UniProtKB=Q0U1N8	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_01980\|UniProtKB=Q5BBV0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G10600\|UniProtKB=Q4WPV6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08499\|UniProtKB=Q7RUP0	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_10712\|UniProtKB=A7EZE5	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_07506\|UniProtKB=Q0UL58	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC26F1.09\|UniProtKB=Q10496	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNK01000\|UniProtKB=Q5K9R8	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_11091\|UniProtKB=A0A0D1E150	Ustilago maydis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_26584\|UniProtKB=F4P8L4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_17582\|UniProtKB=F4PA69	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_13829\|UniProtKB=F4PB55	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_049830\|UniProtKB=C4LUI2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_149900\|UniProtKB=C4M9C8	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_175250\|UniProtKB=C4M3A4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_165290\|UniProtKB=C4M207	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_009910\|UniProtKB=C4M0Q6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_010690\|UniProtKB=C4LYV6	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0282303\|UniProtKB=Q54SQ5	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152459\|UniProtKB=F0ZLE9	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0277967\|UniProtKB=Q54Z16	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_157872\|UniProtKB=F1A078	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0276961\|UniProtKB=Q550W0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_155283\|UniProtKB=F0ZTK3	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0279511\|UniProtKB=Q54WP7	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0290597\|UniProtKB=Q54FT8	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0278181\|UniProtKB=Q54YL8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_81386\|UniProtKB=F0ZTB8	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_27_1990\|UniProtKB=E9ADH9	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_36_6080\|UniProtKB=Q4Q0F2	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_36_6070\|UniProtKB=Q4Q0F3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.6k15.1790\|UniProtKB=Q38A99	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb10.6k15.1770\|UniProtKB=Q38A97	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_413950\|UniProtKB=A2EC67	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_100820\|UniProtKB=A2DJG6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_186160\|UniProtKB=A2D8Q9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_173580\|UniProtKB=A2EVI1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_257470\|UniProtKB=A2ELI1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_434540\|UniProtKB=A2DSN7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_416490\|UniProtKB=A2EQP1	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0907200\|UniProtKB=Q8I379	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00010589001\|UniProtKB=A0CUC2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028721001\|UniProtKB=A0BGL9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012403001\|UniProtKB=A0D1G2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016364001\|UniProtKB=A0DES1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026900001\|UniProtKB=A0EGY5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_38973\|UniProtKB=B8BT08	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_42283\|UniProtKB=B8CBV5	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GE06_PHYRM\|UniProtKB=H3GE06	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_17g737050v5\|UniProtKB=A0A2K3CRG0	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g727450v5\|UniProtKB=A0A2K3CQR5	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00006p00260160\|UniProtKB=W1P7G8	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_345G00210\|UniProtKB=A0A0K9P7B7	Zostera marina	O
SETIT\|EnsemblGenome=SETIT_001847mg\|UniProtKB=K3XIX4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G048700\|UniProtKB=C5WW68	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb061500\|UniProtKB=B4FML3	Zea mays	O
ORYSJ\|EnsemblGenome=Os08g0412600\|UniProtKB=Q0J5Q6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g35740v3\|UniProtKB=I1I704	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_5g14360v3\|UniProtKB=A0A0Q3E620	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0335010\|UniProtKB=M0UHA6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4B02G030800\|UniProtKB=A0A3B6IJM8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G282500\|UniProtKB=A0A3B6HWP5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G028300\|UniProtKB=A0A3B6JCY5	Triticum aestivum	O
NELNU\|Gene=LOC104600532\|UniProtKB=A0A1U8A3Y6	Nelumbo nucifera	O
SPIOL\|Gene=LOC110786837\|UniProtKB=A0A9R0JU41	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0652311\|UniProtKB=A0A251SJ58	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200081990\|UniProtKB=A0A9R1WBN0	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008955mg\|UniProtKB=A0A022PSQ4	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_33923\|UniProtKB=A0A1U8DXE5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400018291\|UniProtKB=M1BK64	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g101090.3\|UniProtKB=A0A3Q7EQM5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107761476\|UniProtKB=A0A1S3X5M6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107812048\|UniProtKB=A0A1S4BUR5	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g01287\|UniProtKB=D7SMJ1	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I02101\|UniProtKB=A0A059AR97	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra023546\|UniProtKB=M4E443	Brassica campestris	O
ARATH\|TAIR=locus=2146117\|UniProtKB=O81347	Arabidopsis thaliana	O
BRACM\|EnsemblGenome=Bra001045\|UniProtKB=M4CA16	Brassica campestris	O
ARATH\|TAIR=locus=2076949\|UniProtKB=Q8LAF3	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107930507\|UniProtKB=A0A1U8LSV3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_019630\|UniProtKB=A0A061EPU7	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g040788mg\|UniProtKB=A0A067F5W8	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_017G109000v3\|UniProtKB=U5FJV7	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G106700v3\|UniProtKB=A9PF38	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_01G106800\|UniProtKB=A0A2C9WK33	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_02G063700\|UniProtKB=A0A251LVX6	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0596820\|UniProtKB=B9SIY8	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_13G049900\|UniProtKB=I1LWY6	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G040100\|UniProtKB=I1N6J6	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g016590\|UniProtKB=A0A072U794	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr10_05480\|UniProtKB=A0A2I4H0C7	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_07690\|UniProtKB=A0A2I4EB80	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G445110\|UniProtKB=A0A0A0KK58	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G243700\|UniProtKB=M5X5K2	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_166276\|UniProtKB=D8QWZ0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_231859\|UniProtKB=D8RL25	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c5_10620\|UniProtKB=A0A2K1KJ89	Physcomitrella patens	O