PANTHER Gene Information   
Gene Symbol(s): Dcr-2
Organism: Drosophila melanogaster
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Gene Name: Endoribonuclease Dcr-2
Gene ID: FBgn0034246
Protein ID: A1ZAW0
Persistent Id: PTN000383765
Alternate Ids:
BAB69959(EMBL-CDS) DCR2_DROME(UniProtKB-ID)
FBtr0086904(Ensembl_TRS) BT128787(EMBL)
Protein Dicer-2 {ECO:0000303|Ref.1}(Synonym) Dcr-2{ECO:0000303|PubMed:21245036,ECO:0000312|FlyBase:FBgn0034246}(Symbol)
FBgn0034246(FlyBase) FBpp0086061(Ensembl_PRO)
36993(GeneID) NM_079054(refSeq)
FBgn0034246(Ensembl) Q95YG3(AltAccession)
3.1.26.3 {ECO:0000269|PubMed:15066283, ECO:0000269|PubMed:21419681, ECO:0000269|PubMed:27872309, ECO:0000269|PubMed:28416567, ECO:0000269|PubMed:29550490, ECO:0000269|PubMed:32843367, ECO:0000269|PubMed:34257295}(EC) 22026807(GI)
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PANTHER Classification
PANTHER Family: DICER-RELATED (PTHR14950)
PANTHER Subfamily: ENDORIBONUCLEASE DCR-2 (PTHR14950:SF36)  
PANTHER GO-slim Molecular Function: DNA endonuclease activity
RNA endonuclease activity
RNA binding
PANTHER GO-slim Biological Process: execution phase of apoptosis
pre-miRNA processing
siRNA processing
cellular component disassembly
DNA catabolic process
PANTHER GO-slim Cellular Component: nucleus
endoribonuclease complex
cytoplasm
PANTHER protein class:
Pathway Categories: No pathway information available
GO MF Complete: ATP hydrolysis activity, ATP binding, RNA binding, ribonuclease III activity, protein binding, ATP-dependent activity, acting on RNA, siRNA binding, deoxyribonuclease I activity, mRNA 3'-UTR binding
GO BP Complete: regulatory ncRNA-mediated post-transcriptional gene silencing, RNA processing, positive regulation of defense response to virus by host, dosage compensation by hyperactivation of X chromosome, detection of virus, positive regulation of Toll signaling pathway, lncRNA catabolic process, cellular response to virus, global gene silencing by mRNA cleavage, locomotory behavior, RNAi-mediated antiviral immune response, positive regulation of innate immune response, apoptotic DNA fragmentation, heterochromatin formation, defense response to virus, siRNA processing, RISC complex assembly
GO CC Complete: nucleus, perinuclear region of cytoplasm, cytoplasm, RISC-loading complex, RISC complex
Reactome Pathways: -