PANTHER Gene Information

Gene Symbol(s):

PTP4A3

Organism:

Bos taurus

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Gene Name:

Protein tyrosine phosphatase type IVA 3

Gene ID:

ENSBTAG00000046467

Protein ID:

A2VDT1

Persistent Id:

PTN001155334

Alternate Ids:

BC133386(EMBL)	ENSBTAP00000056717(Ensembl_PRO)
PTP4A3(Symbol)	ENSBTAT00000086143(Ensembl_TRS)
TP4A3(Synonym)	139949068(GI)
ENSBTAG00000046467(Ensembl)	AAI33387(EMBL-CDS)
TP4A3_BOVIN(UniProtKB-ID)	XP_005215181(refSeq)
100137722(GeneID)	3.1.3.48(EC)
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PANTHER Classification

PANTHER Family:	TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE (PTHR23339)
PANTHER Subfamily:	PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3 (PTHR23339:SF119)
PANTHER GO-slim Molecular Function:	protein tyrosine phosphatase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytoplasm nucleus
PANTHER protein class:	protein phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	non-membrane spanning protein tyrosine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine phosphatase activity, metal-dependent, histone H2AXY142 phosphatase activity
GO BP Complete:	chromatin remodeling, Notch signaling pathway, positive regulation of establishment of protein localization, cellular response to leukemia inhibitory factor, positive regulation of non-canonical NF-kappaB signal transduction, regulation of DNA-templated transcription, endothelial cell migration, regulation of vascular endothelial growth factor signaling pathway, positive regulation of vascular permeability
GO CC Complete:	nucleus, early endosome, cytoplasm, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9636\|UniProtKB=O75365	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020631.6\|UniProtKB=A0A2I3REL6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000037356.1\|UniProtKB=A0A2I2YS06	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019392.4\|UniProtKB=F6T1U3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1277098\|UniProtKB=Q9D658	Mus musculus	LDO
RAT\|RGD=1308687\|UniProtKB=B0K032	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000036569.3\|UniProtKB=A0A286ZWD0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000030951.3\|UniProtKB=F6X4H9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000038613.3\|UniProtKB=A0A2I2UKX7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013289.1\|UniProtKB=A0A8I3RXG1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000651.4\|UniProtKB=F6SUC7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000029465.2\|UniProtKB=A0A6I8NR98	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009335.1\|UniProtKB=A0A1D5PMZ4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000749.3\|UniProtKB=G1K8Q4	Anolis carolinensis	LDO
XENLA\|Gene=ptp4a3.S\|UniProtKB=A0A1L8FU16	Xenopus laevis	LDO
XENLA\|Gene=ptp4a3.L\|UniProtKB=Q6L7J1	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000004793.2\|UniProtKB=A0A3B3H397	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-2635\|UniProtKB=E7FA22	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-2220\|UniProtKB=Q6NX92	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007367.1\|UniProtKB=W5MKM2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021101.1\|UniProtKB=A0A1W3JGN6	Ciona intestinalis	LDO
BRAFL\|Gene=PRL\|UniProtKB=M4TBT2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC763053\|UniProtKB=A0A7M7N2C3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004184\|UniProtKB=G5EG43	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG14314\|UniProtKB=A8XJR2	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0024734\|UniProtKB=O61722	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008708\|UniProtKB=Q7PPM5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004794\|UniProtKB=D6W854	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_305822\|UniProtKB=E9HWB4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015996\|UniProtKB=B7P1T4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG157129\|UniProtKB=T1EM68	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG193782\|UniProtKB=T1FVC7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g227192\|UniProtKB=A7SGK4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG27879\|UniProtKB=B3S204	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_33242\|UniProtKB=A9V4C1	Monosiga brevicollis	LDO
CRYNJ\|EnsemblGenome=CNI04350\|UniProtKB=Q5KAZ5	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05478\|UniProtKB=A0A0D1DPZ6	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_00746\|UniProtKB=E3JTT3	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_25905\|UniProtKB=F4P5Z8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16063\|UniProtKB=F4NZ92	Batrachochytrium dendrobatidis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_6575\|UniProtKB=F4NW52	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19332\|UniProtKB=F4P0M7	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_039050\|UniProtKB=C4LZS6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_044560\|UniProtKB=C4LT78	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0272662\|UniProtKB=Q86IL4	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0292024\|UniProtKB=Q54DU9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_159842\|UniProtKB=F1A540	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_16_0250\|UniProtKB=Q4QEZ5	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_16_0230\|UniProtKB=Q4QEZ7	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.8.5780\|UniProtKB=Q57YH9	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_308020\|UniProtKB=A2EGK1	Trichomonas vaginalis	LDO
PHYRM\|Gene=H3GEQ3_PHYRM\|UniProtKB=H3GEQ3	Phytophthora ramorum	O
AMBTC\|EnsemblGenome=AMTR_s00003p00177190\|UniProtKB=W1P8C4	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_221G00190\|UniProtKB=A0A0K9PJ95	Zostera marina	O
MUSAM\|EnsemblGenome=Ma02_g01870\|UniProtKB=A0A804HYA4	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_033940mg\|UniProtKB=K4A4Y6	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G178600\|UniProtKB=A0A1Z5S6R1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb049240\|UniProtKB=A0A804M069	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0586700\|UniProtKB=Q6F2V0	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g15377v3\|UniProtKB=A0A0Q3J8W6	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0373440\|UniProtKB=F2DJM0	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G143300\|UniProtKB=A0A3B6HW81	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G166300\|UniProtKB=A0A3B6JKA8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G156100\|UniProtKB=A0A3B6IQE5	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_011723\|UniProtKB=A0A1U7ZDE6	Nelumbo nucifera	O
SPIOL\|Gene=LOC110775483\|UniProtKB=A0A9R0HRR6	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0672381\|UniProtKB=A0A251S4P2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900454970\|UniProtKB=A0A9R1UEL4	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000330mg\|UniProtKB=A0A022S4L2	Erythranthe guttata	O
SOLLC\|EnsemblGenome=Solyc01g068590.3\|UniProtKB=A0A3Q7EH77	Solanum lycopersicum	O
TOBAC\|Gene=LOC107810619\|UniProtKB=A0A1S4BQ16	Nicotiana tabacum	O
TOBAC\|Gene=LOC107759528\|UniProtKB=A0A1S3WZ39	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi07g00545\|UniProtKB=D7U2V9	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K00763\|UniProtKB=A0A059A0W8	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_K00546\|UniProtKB=A0A058ZY71	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00090836001\|UniProtKB=A0A078FV87	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00054070001\|UniProtKB=A0A078H3R6	Brassica napus	O
BRACM\|EnsemblGenome=Bra038886\|UniProtKB=M4FCR7	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A09P54080.1\|UniProtKB=A0A078FDJ2	Brassica napus	O
BRACM\|EnsemblGenome=Bra007651\|UniProtKB=M4CTV7	Brassica campestris	O
ARATH\|TAIR=locus=2079577\|UniProtKB=F4IX22	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107930496\|UniProtKB=A0A1U8LSU3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107910514\|UniProtKB=A0A1U8JUB0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912257\|UniProtKB=A0A1U8K5C5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107897166\|UniProtKB=A0A1U8IIS8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924589\|UniProtKB=A0A1U8L7L7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107916664\|UniProtKB=A0A1U8KG19	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_004984\|UniProtKB=A0A061DTT1	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g0008351mg\|UniProtKB=A0A067HFS8	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_002G184400v3\|UniProtKB=B9GRU9	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_014G109900v3\|UniProtKB=U5FPV5	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_01G236800\|UniProtKB=A0A2C9WNM0	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1341920\|UniProtKB=B9RN01	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_19G223200\|UniProtKB=K7MZP3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_03G226200\|UniProtKB=I1JQZ4	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g111030\|UniProtKB=G7KVH5	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_20G089300\|UniProtKB=I1NES0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G140500\|UniProtKB=I1LAW5	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g085300\|UniProtKB=G7IAF7	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr08_10350\|UniProtKB=A0A2I4FMQ9	Juglans regia	O
JUGRE\|EnsemblGenome=Jr08_10340\|UniProtKB=A0A2I4FMT8	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_17480\|UniProtKB=A0A2I4GGU2	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G001780\|UniProtKB=A0A0A0KB71	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G000300\|UniProtKB=A0A251PW22	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_86711\|UniProtKB=D8R7J1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_164100\|UniProtKB=D8QMN2	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c5_15420\|UniProtKB=A9T5M7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c25_5940\|UniProtKB=A0A2K1IDY8	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0022s0091\|UniProtKB=A0A2R6XD03	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_002210100\|UniProtKB=A0A1Y1I2I9	Klebsormidium nitens	O
PLAF7\|EnsemblGenome=PF3D7_1113100\|UniProtKB=Q8IIN1	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_38780\|UniProtKB=B8CG64	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GU63_PHYRM\|UniProtKB=H3GU63	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g054550v5\|UniProtKB=A0A2K3E8A0	Chlamydomonas reinhardtii	LDO
CHLRE\|EnsemblGenome=CHLRE_01g054600v5\|UniProtKB=A0A2K3E8A1	Chlamydomonas reinhardtii	LDO
CHLRE\|EnsemblGenome=CHLRE_03g187500v5\|UniProtKB=A0A2K3DY49	Chlamydomonas reinhardtii	O
NITMS\|EnsemblGenome=Nmar_1760\|UniProtKB=A9A3V6	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0177\|UniProtKB=B1L3A8	Korarchaeum cryptofilum	LDO
KORCO\|EnsemblGenome=Kcr_0609\|UniProtKB=B1L4I3	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO2453\|UniProtKB=Q97VZ7	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE1536\|UniProtKB=Q8ZX04	Pyrobaculum aerophilum	LDO
METJA\|EnsemblGenome=MJ_ECL20\|UniProtKB=Q60280	Methanocaldococcus jannaschii	LDO
METJA\|EnsemblGenome=MJ_0215\|UniProtKB=Q57668	Methanocaldococcus jannaschii	LDO
THEKO\|EnsemblGenome=TK0241\|UniProtKB=Q8X270	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_0153\|UniProtKB=A9WBK0	Chloroflexus aurantiacus	LDO
DEIRA\|EnsemblGenome=DR_2161\|UniProtKB=Q9RSG3	Deinococcus radiodurans	LDO
GLOVI\|Gene=Q7NLX9_GLOVI\|UniProtKB=Q7NLX9	Gloeobacter violaceus	LDO
SHEON\|Gene_OrderedLocusName=SO_0090\|UniProtKB=Q8EKK2	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_1070\|UniProtKB=Q9KT35	Vibrio cholerae	LDO