PANTHER Gene Information

Gene Symbol(s):

PRAMEF22

Organism:

Homo sapiens

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Gene Name:

PRAME family member 22

Gene ID:

HGNC:34393

Protein ID:

A3QJZ6

Enhancers:

View enhancers for HUMAN|HGNC=34393|UniProtKB=A3QJZ6

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002494351

Alternate Ids:

CR589905(EMBL)	NP_001094101(refSeq)
A6NMM3(AltAccession)	154800493(GI)
653606(GeneID)	PRA22_HUMAN(UniProtKB-ID)
PRAMEF22{ECO:0000312\|HGNC:HGNC:34393}(Symbol)	HGNC:34393(HGNC)
PRA22(Synonym)
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PANTHER Classification

PANTHER Family:	SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 (PTHR14224)
PANTHER Subfamily:	PRAME FAMILY MEMBER 18-RELATED (PTHR14224:SF79)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin-like ligase-substrate adaptor activity
GO BP Complete:	proteasome-mediated ubiquitin-dependent protein catabolic process, negative regulation of DNA-templated transcription, negative regulation of cell differentiation, negative regulation of apoptotic process, positive regulation of cell population proliferation
GO CC Complete:	cytoplasm, Cul2-RING ubiquitin ligase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
GORGO\|Ensembl=ENSGGOG00000027485.2\|UniProtKB=G3RVR5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000058407.1\|UniProtKB=A0A5F8AD24	Macaca mulatta	O
MOUSE\|MGI=MGI=2156391\|UniProtKB=Q810Y8	Mus musculus	O
MOUSE\|MGI=MGI=3650199\|UniProtKB=A2ASJ1	Mus musculus	O
MOUSE\|MGI=MGI=3651261\|UniProtKB=L7MU96	Mus musculus	O
RAT\|RGD=1565990\|UniProtKB=F1M288	Rattus norvegicus	O
RAT\|RGD=1587447\|UniProtKB=F1LYT8	Rattus norvegicus	O
MOUSE\|MGI=MGI=3525148\|UniProtKB=Q66JY9	Mus musculus	O
MOUSE\|MGI=MGI=3649498\|UniProtKB=Q4FZF9	Mus musculus	O
MOUSE\|MGI=MGI=3649968\|UniProtKB=A2ASI9	Mus musculus	O
MOUSE\|MGI=MGI=3650204\|UniProtKB=A2ASJ0	Mus musculus	O
MOUSE\|MGI=MGI=3651680\|UniProtKB=B1ARV5	Mus musculus	O
RAT\|RGD=1561813\|UniProtKB=F1M1R3	Rattus norvegicus	O
MOUSE\|MGI=MGI=3781326\|UniProtKB=A0A0J9YU88	Mus musculus	O
MOUSE\|MGI=MGI=3704250\|UniProtKB=A0A0J9YVD0	Mus musculus	O
MOUSE\|MGI=MGI=2681870\|UniProtKB=Q6P8K3	Mus musculus	O
MOUSE\|MGI=MGI=3704105\|UniProtKB=J3QMM8	Mus musculus	O
RAT\|RGD=1565660\|UniProtKB=D4A6V4	Rattus norvegicus	O
RAT\|RGD=1591399\|UniProtKB=A0A8I6ACX9	Rattus norvegicus	O
RAT\|RGD=6503293\|UniProtKB=A0A8I5ZX05	Rattus norvegicus	O
RAT\|RGD=150342112\|UniProtKB=A0A8I6AC03	Rattus norvegicus	O
MOUSE\|MGI=MGI=2684051\|UniProtKB=Q4G0C7	Mus musculus	O
MOUSE\|MGI=MGI=3650478\|UniProtKB=A2A8N2	Mus musculus	O
MOUSE\|MGI=MGI=2140706\|UniProtKB=Q3UX49	Mus musculus	O
MOUSE\|MGI=MGI=3649971\|UniProtKB=A2AGW6	Mus musculus	O
MOUSE\|MGI=MGI=2684035\|UniProtKB=Q7TPX8	Mus musculus	O
MOUSE\|MGI=MGI=3650203\|UniProtKB=Q4VAD2	Mus musculus	O
MOUSE\|MGI=MGI=2140708\|UniProtKB=A2A958	Mus musculus	O
MOUSE\|MGI=MGI=2679150\|UniProtKB=E9Q5G7	Mus musculus	O
MOUSE\|MGI=MGI=2684047\|UniProtKB=Q3UWY1	Mus musculus	O
MOUSE\|MGI=MGI=3650237\|UniProtKB=A2A8N0	Mus musculus	O
MOUSE\|MGI=MGI=3704393\|UniProtKB=L7N1Y3	Mus musculus	O
MOUSE\|MGI=MGI=3649972\|UniProtKB=A2AGW7	Mus musculus	O
RAT\|RGD=1565680\|UniProtKB=F1M886	Rattus norvegicus	O
RAT\|RGD=1306186\|UniProtKB=F7F487	Rattus norvegicus	O
MOUSE\|MGI=MGI=3795847\|UniProtKB=L7MTS5	Mus musculus	O
MOUSE\|MGI=MGI=3652120\|UniProtKB=B1AUV4	Mus musculus	O
MOUSE\|MGI=MGI=3588238\|UniProtKB=Q3UTC0	Mus musculus	O
RAT\|RGD=150341028\|UniProtKB=A0A8I6G7M6	Rattus norvegicus	O
RAT\|RGD=15004265\|UniProtKB=F1M3U2	Rattus norvegicus	O
RAT\|RGD=150343512\|UniProtKB=A0A8I6G355	Rattus norvegicus	O
MOUSE\|MGI=MGI=2156390\|UniProtKB=Q810Y9	Mus musculus	O
RAT\|RGD=1565946\|UniProtKB=D3ZD67	Rattus norvegicus	O
MOUSE\|MGI=MGI=3779756\|UniProtKB=A0A0J9YUM1	Mus musculus	O
MOUSE\|MGI=MGI=2141041\|UniProtKB=D3YUJ6	Mus musculus	O
MOUSE\|MGI=MGI=3781318\|UniProtKB=J3QK78	Mus musculus	O
MOUSE\|MGI=MGI=3781437\|UniProtKB=D3YUK0	Mus musculus	O
MOUSE\|MGI=MGI=1261918\|UniProtKB=Q499F0	Mus musculus	O
MOUSE\|MGI=MGI=3781282\|UniProtKB=J3QPH3	Mus musculus	O
MOUSE\|MGI=MGI=3647817\|UniProtKB=K9J7D1	Mus musculus	O
MOUSE\|MGI=MGI=3615333\|UniProtKB=Q3UL33	Mus musculus	O
MOUSE\|MGI=MGI=3704104\|UniProtKB=A0A0J9YU01	Mus musculus	O
MOUSE\|MGI=MGI=2141341\|UniProtKB=E9PWI7	Mus musculus	O
MOUSE\|MGI=MGI=3779602\|UniProtKB=A0A0J9YUV1	Mus musculus	O
MOUSE\|MGI=MGI=3779601\|UniProtKB=L7N456	Mus musculus	O
MOUSE\|MGI=MGI=3704103\|UniProtKB=A0A0J9YU00	Mus musculus	O
MOUSE\|MGI=MGI=3646599\|UniProtKB=A0A571BEB1	Mus musculus	O
RAT\|RGD=1565129\|UniProtKB=D3ZCB3	Rattus norvegicus	O
RAT\|RGD=41183035\|UniProtKB=A0A8I6AK48	Rattus norvegicus	O
RAT\|RGD=11357449\|UniProtKB=A0A8I6B4R9	Rattus norvegicus	O
RAT\|RGD=7639242\|UniProtKB=A0A8I6AHD7	Rattus norvegicus	O
RAT\|RGD=150343754\|UniProtKB=A0A8I6AWA1	Rattus norvegicus	O
RAT\|RGD=1562932\|UniProtKB=A0A8I6GK57	Rattus norvegicus	O
RAT\|RGD=41119288\|UniProtKB=D3ZXA7	Rattus norvegicus	O
RAT\|RGD=1559654\|UniProtKB=A0A8I5ZKI3	Rattus norvegicus	O
RAT\|RGD=6499239\|UniProtKB=A0A8I5ZL15	Rattus norvegicus	O
RAT\|RGD=150343001\|UniProtKB=A0A8I6A7A8	Rattus norvegicus	O
RAT\|RGD=1561699\|UniProtKB=A0A8I6A1M8	Rattus norvegicus	O
RAT\|RGD=1561977\|UniProtKB=A0A8I6A5E7	Rattus norvegicus	O
RAT\|RGD=40959535\|UniProtKB=A0A8I6AKQ0	Rattus norvegicus	O
RAT\|RGD=2323210\|UniProtKB=A0A8I5Y4Z4	Rattus norvegicus	O
RAT\|RGD=150342025\|UniProtKB=A0A8I6A3N0	Rattus norvegicus	O
RAT\|RGD=1561226\|UniProtKB=D4ADJ1	Rattus norvegicus	O
MOUSE\|MGI=MGI=3650231\|UniProtKB=A2AGW8	Mus musculus	O
MOUSE\|MGI=MGI=2156389\|UniProtKB=Q7TPY4	Mus musculus	O
MOUSE\|MGI=MGI=3703005\|UniProtKB=A2ASJ3	Mus musculus	O
MOUSE\|MGI=MGI=3650232\|UniProtKB=A2AGW5	Mus musculus	O
MOUSE\|MGI=MGI=3649940\|UniProtKB=A2A8M8	Mus musculus	O
RAT\|RGD=1587378\|UniProtKB=A0A8I5ZUB8	Rattus norvegicus	O
RAT\|RGD=40938591\|UniProtKB=A0A0G2K6X8	Rattus norvegicus	O
MOUSE\|MGI=MGI=2140473\|UniProtKB=Q8CE24	Mus musculus	O
RAT\|RGD=1564061\|UniProtKB=D4A3H1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012389.5\|UniProtKB=F1MZN5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000046630.2\|UniProtKB=G3X7L2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000031836.3\|UniProtKB=A0A8W4F7C7	Sus scrofa	O
BOVIN\|Ensembl=ENSBTAG00000053200.1\|UniProtKB=A0A3Q1NAZ5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000031507.4\|UniProtKB=A0A3Q1MCY8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000059389.1\|UniProtKB=A0A287BP72	Sus scrofa	O
BOVIN\|Ensembl=ENSBTAG00000052006.1\|UniProtKB=A0A3Q1MMC5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054186.1\|UniProtKB=F1N7H9	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000051639.1\|UniProtKB=A0A3Q1M2I9	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054788.1\|UniProtKB=A0A3Q1LQQ4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000050338.1\|UniProtKB=A0A3Q1M8P1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049796.1\|UniProtKB=A0A3Q1NMN6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054313.1\|UniProtKB=A0A3Q1MRX0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000003444.4\|UniProtKB=F1RF54	Sus scrofa	O
BOVIN\|Ensembl=ENSBTAG00000050422.1\|UniProtKB=A0A3Q1LSC7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000053475.1\|UniProtKB=A0A3Q1LFW5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000024791.5\|UniProtKB=A0A3Q1M8V4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054475.1\|UniProtKB=A0A3Q1MBC8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000052938.1\|UniProtKB=A0A3Q1MKG7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054147.1\|UniProtKB=A0A3Q1NLD3	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000051707.1\|UniProtKB=A0A3Q1N0U5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000033480.3\|UniProtKB=A0A8D0T3C5	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000055083.1\|UniProtKB=A0A286ZTE8	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000037632.3\|UniProtKB=A0A8W4FNU4	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000033129.3\|UniProtKB=A0A286ZRG3	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000040680.3\|UniProtKB=A0A287AX84	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010285.4\|UniProtKB=A0A3Q2HKE7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000023782.4\|UniProtKB=A0A5F5XID7	Felis catus	O
MONDO\|Ensembl=ENSMODG00000050338.1\|UniProtKB=A0A5F8G644	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011150.4\|UniProtKB=F7BY71	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011022.4\|UniProtKB=F7FVE0	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011094.4\|UniProtKB=F7FVN5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000044257.1\|UniProtKB=A0A6I8NXF3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010007993.1\|UniProtKB=A0A8V0XZU8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000010645.4\|UniProtKB=H9GGM6	Anolis carolinensis	O
XENLA\|Gene=lrrc14\|UniProtKB=Q640Z9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5844980\|UniProtKB=F6UIV6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000010754.2\|UniProtKB=H2M4W3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-160728-69\|UniProtKB=E7F4Y9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000008819.1\|UniProtKB=W5MQR8	lepisosteus oculatus	O
BRAFL\|Gene=LOC118405879\|UniProtKB=A0A9J7HNM2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414961\|UniProtKB=A0A9J7L3F1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414414\|UniProtKB=A0A9J7L2B1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115923441\|UniProtKB=A0A7M7NSD8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105443597\|UniProtKB=A0A7M7NUN2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105445134\|UniProtKB=A0A7M7NQ53	Strongylocentrotus purpuratus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244335\|UniProtKB=A7SCP0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG55619\|UniProtKB=B3RVE0	Trichoplax adhaerens	O