PANTHER Gene Information

Gene Symbol(s):

TOR2A

Organism:

Bos taurus

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Gene Name:

Torsin-2A

Gene ID:

ENSBTAG00000013510

Protein ID:

A4FUH1

Persistent Id:

PTN008505222

Alternate Ids:

ENSBTAG00000013510(Ensembl)	TOR2A(Symbol)
205831096(GI)	TOR2A_BOVIN(UniProtKB-ID)
Torsin family 2 member A(Synonym)	534311(GeneID)
AAI14886(EMBL-CDS)	BC114885(EMBL)
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PANTHER Classification

PANTHER Family:	TORSIN (PTHR10760)
PANTHER Subfamily:	TORSIN-2A (PTHR10760:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	endoplasmic reticulum lumen nuclear envelope
PANTHER protein class:	chaperone

Pathway Categories:

Parkinson disease

Torsin A

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, identical protein binding
GO BP Complete:	chaperone cofactor-dependent protein refolding
GO CC Complete:	nuclear envelope, endoplasmic reticulum lumen

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11996\|UniProtKB=Q5JU69	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021396.6\|UniProtKB=H2QXX6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011044.3\|UniProtKB=G3R628	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016429.4\|UniProtKB=H9FT45	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1353596\|UniProtKB=Q8R1J9	Mus musculus	LDO
RAT\|RGD=1359111\|UniProtKB=Q6AYR4	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000005619.5\|UniProtKB=F1RS09	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014482.4\|UniProtKB=A0A9L0RU30	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000046339.2\|UniProtKB=M3WVJ5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005640.1\|UniProtKB=A0A8I3MRM3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005518.4\|UniProtKB=F7G5K0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040414.1\|UniProtKB=A0A6I8PFT8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028096.1\|UniProtKB=A0A8V1AC68	Gallus gallus	LDO
XENLA\|Gene=LOC108709579\|UniProtKB=A0A1L8H7S4	Xenopus laevis	O
XENLA\|Gene=tor2a\|UniProtKB=Q68F68	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5806617\|UniProtKB=Q28G83	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000020659.2\|UniProtKB=H2N2B0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050913-60\|UniProtKB=Q4V8W5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002778.1\|UniProtKB=W5M4G1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023107.1\|UniProtKB=H2XLI1	Ciona intestinalis	O
BRAFL\|Gene=LOC118421275\|UniProtKB=A0A9J7MZK0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404402\|UniProtKB=A0A9J7HGS7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420993\|UniProtKB=A0A9J7MZ01	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420613\|UniProtKB=A0A9J7LI37	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_128102\|UniProtKB=C3Z7Y3	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115926202\|UniProtKB=A0A7M7P6W3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC753283\|UniProtKB=A0A7M7P5K9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575885\|UniProtKB=A0A7M7P5Q6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446497\|UniProtKB=A0A7M7T4T6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892342\|UniProtKB=A0A7M7T4I6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592199\|UniProtKB=A0A7M7PR66	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC577447\|UniProtKB=A0A7M7RCT9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006598\|UniProtKB=Q9XXG5	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00006597\|UniProtKB=O45271	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003870\|UniProtKB=Q95NU5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG21284\|UniProtKB=A8XZR7	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG03231\|UniProtKB=A8WSH7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00114552\|UniProtKB=A0A2A6CF20	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0030803\|UniProtKB=Q9VX97	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0025615\|UniProtKB=O77277	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029921\|UniProtKB=A0A903XZ27	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000824\|UniProtKB=D6W8J5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_103087\|UniProtKB=E9GIC9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_129381\|UniProtKB=E9H4U5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW017089\|UniProtKB=B7PA07	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017088\|UniProtKB=B7PA06	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG176967\|UniProtKB=T1FB29	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG86403\|UniProtKB=T1G6B7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221156\|UniProtKB=A7T210	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200001\|UniProtKB=A7RP69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g142536\|UniProtKB=A7T211	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241618\|UniProtKB=A7RYS7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98049\|UniProtKB=A7RYS5	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG58752\|UniProtKB=B3S3K1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG33759\|UniProtKB=B3SD48	Trichoplax adhaerens	O
DICDI\|dictyBase=DDB_G0268156\|UniProtKB=Q55FE2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95750\|UniProtKB=F1A0B2	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_09_0820\|UniProtKB=Q4QHU2	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.52.0010\|UniProtKB=Q382P2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_24_2220\|UniProtKB=Q4QAA8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.8.6020\|UniProtKB=Q57YK3	Trypanosoma brucei	O
PHYRM\|Gene=H3GE23_PHYRM\|UniProtKB=H3GE23	Phytophthora ramorum	O
PHYRM\|Gene=H3GDH8_PHYRM\|UniProtKB=H3GDH8	Phytophthora ramorum	O
PHYRM\|Gene=H3HAG1_PHYRM\|UniProtKB=H3HAG1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_10g443801v5\|UniProtKB=A0A2K3DAP1	Chlamydomonas reinhardtii	O