PANTHER Gene Information

Gene Symbol(s):

met-1

Organism:

Caenorhabditis elegans

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Gene Name:

Histone-lysine N-methyltransferase

Gene ID:

WBGene00016603

Protein ID:

A4LBC2

Persistent Id:

PTN000526562

Alternate Ids:

WBGene00016603(Ensembl)	C43E11.3a(WormBase_TRS)
NP_491340(refSeq)	CCD65166(EMBL-CDS)
BX284601(EMBL)	A4LBC2_CAEEL(UniProtKB-ID)
351050564(GI)	A4LBC2(Synonym)
WBGene00016603(WormBase)	CE30503(WormBase_PRO)
172026(GeneID)
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PANTHER Classification

PANTHER Family:	SET DOMAIN PROTEINS (PTHR22884)
PANTHER Subfamily:	NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN-RELATED (PTHR22884:SF413)
PANTHER GO-slim Molecular Function:	histone methyltransferase activity protein-lysine N-methyltransferase activity
PANTHER GO-slim Biological Process:	regulation of DNA-templated transcription
PANTHER GO-slim Cellular Component:	chromatin nucleus
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	histone H3 methyltransferase activity, histone methyltransferase activity, histone H3K36 methyltransferase activity, transferase activity, protein-lysine N-methyltransferase activity
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of vulval development, chromatin remodeling, regulation of DNA-templated transcription
GO CC Complete:	nucleus, chromosome, chromatin

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
CIOIN\|Ensembl=ENSCING00000014316.2\|UniProtKB=F6UMR8	Ciona intestinalis	LDO
CAEBR\|Gene_ORFName=CBG06706\|UniProtKB=A8X2W9	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG_12181\|UniProtKB=A8XF20	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00097911\|UniProtKB=A0A2A6BK97	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00090784\|UniProtKB=A0A2A6BU52	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278015\|UniProtKB=A0A2A6BC90	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00094649\|UniProtKB=A0A2A6BZN8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0039559\|UniProtKB=Q8MT36	Drosophila melanogaster	LDO
DROME\|FlyBase=FBgn0030486\|UniProtKB=Q9VYD1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004656\|UniProtKB=A0A1S4GMB4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014310\|UniProtKB=D6WL79	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_319776\|UniProtKB=E9GMT3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW013039\|UniProtKB=B7QG36	Ixodes scapularis	LDO
TRIAD\|EnsemblGenome=TriadG54228\|UniProtKB=B3RRG4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34767\|UniProtKB=A9VDX1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_26994\|UniProtKB=A9V3J3	Monosiga brevicollis	LDO
YEAST\|SGD=S000003704\|UniProtKB=P46995	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL128C\|UniProtKB=Q757Y8	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000174178\|UniProtKB=Q59XV0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E18260g\|UniProtKB=Q6C5G5	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08825\|UniProtKB=Q5ASA5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G08460\|UniProtKB=Q4WUH3	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_5G06000\|UniProtKB=Q4WTT2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00269\|UniProtKB=Q7RZU4	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07089\|UniProtKB=A7EP40	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01198\|UniProtKB=Q0V466	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC29B12.02c\|UniProtKB=O14026	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02873\|UniProtKB=B6K1E8	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNG03810\|UniProtKB=P0CO28	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00400\|UniProtKB=A0A0D1ECE5	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_02500\|UniProtKB=Q4PBL3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_09875\|UniProtKB=E3KF80	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_90118\|UniProtKB=F4P7F7	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0268132\|UniProtKB=Q55FF7	Dictyostelium discoideum	LDO
PLAF7\|EnsemblGenome=PF3D7_1322100\|UniProtKB=Q8IE95	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00002604001\|UniProtKB=A0DQ87	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003275001\|UniProtKB=A0DZ39	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00004957001\|UniProtKB=A0BJ67	Paramecium tetraurelia	O
PHYRM\|Gene=H3GBS0_PHYRM\|UniProtKB=H3GBS0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_09g392542v5\|UniProtKB=A0A2K3DEA3	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00017p00244380\|UniProtKB=W1PFJ4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_81G00680\|UniProtKB=A0A0K9NPD3	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g08230\|UniProtKB=A0A804KHA4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016071mg\|UniProtKB=K3YP79	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G176000\|UniProtKB=C5XU80	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb243610\|UniProtKB=A0A804PIS6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0554000\|UniProtKB=A0A0P0VK92	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g45727v3\|UniProtKB=I1IAH5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0096180\|UniProtKB=A0A287GVI3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2B02G015500\|UniProtKB=A0A3B6BWX3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G005000\|UniProtKB=A0A3B6AP47	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS2D02G007100\|UniProtKB=A0A2X0RZK3	Triticum aestivum	LDO
NELNU\|Gene=LOC104606674\|UniProtKB=A0A1U8B2S4	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104605844\|UniProtKB=A0A1U8AML9	Nelumbo nucifera	O
SPIOL\|Gene=LOC110782002\|UniProtKB=A0A9R0I2R6	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0220251\|UniProtKB=A0A251URZ6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600339350\|UniProtKB=A0A9R1X845	Lactuca sativa	LDO
CAPAN\|EnsemblGenome=T459_12201\|UniProtKB=A0A2G2ZP42	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc04g057880.3\|UniProtKB=A0A3Q7G694	Solanum lycopersicum	O
CAPAN\|EnsemblGenome=T459_16854\|UniProtKB=A0A1U8GVV4	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc06g059965.1\|UniProtKB=A0A3Q7GX24	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107811600\|UniProtKB=A0A1S4BT42	Nicotiana tabacum	O
TOBAC\|Gene=LOC107803852\|UniProtKB=A0A1S4B2S7	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_18s0001g01700\|UniProtKB=F6H0H8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F03851\|UniProtKB=A0A059BXH1	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra015678\|UniProtKB=M4DGQ3	Brassica campestris	LDO
ARATH\|TAIR=locus=2196000\|UniProtKB=Q2LAE1	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107910364\|UniProtKB=A0A1U8JY44	Gossypium hirsutum	O
GOSHI\|Gene=LOC107943759\|UniProtKB=A0A1U8N1W6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951494\|UniProtKB=A0A1U8NSU5	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_035213\|UniProtKB=A0A061FIB6	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_005G182100v3\|UniProtKB=A0A2K2AIJ1	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_002G079100v3\|UniProtKB=A0A2K2BF91	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_18G082500\|UniProtKB=A0A251IRL0	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_02G168600\|UniProtKB=A0A2C9WG59	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0561810\|UniProtKB=B9S2T8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_04G245400\|UniProtKB=K7KM54	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G117700\|UniProtKB=K7KUK4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g088625\|UniProtKB=A0A072VB26	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr15_02420\|UniProtKB=A0A2I4GZ46	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr15_02410\|UniProtKB=A0A2I4GZ40	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr06_03350\|UniProtKB=A0A2I4DW19	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G376290\|UniProtKB=A0A0A0KDR4	Cucumis sativus	LDO
SELML\|EnsemblGenome=SELMODRAFT_421873\|UniProtKB=D8SGM1	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_3415\|UniProtKB=D8SCE3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c1_33770\|UniProtKB=A0A7I4C3D4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_12540\|UniProtKB=A0A2K1L195	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0009s0182\|UniProtKB=A0A2R6XLW1	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0192s0005\|UniProtKB=A0A2R6W137	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000810090\|UniProtKB=A0A1Y1I034	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_003730160\|UniProtKB=A0A1Y1IHW9	Klebsormidium nitens	LDO