PANTHER Gene Information

Gene Symbol(s):

Cdep

Organism:

Drosophila melanogaster

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Gene Name:

Moesin_ezrin_radixin homolog 1

Gene ID:

FBgn0265082

Protein ID:

A8JQT5

Persistent Id:

PTN002290654

Alternate Ids:

NM_001104215(refSeq)	A8JQT5_DROME(UniProtKB-ID)
FBgn0265082(Ensembl)	442617466(GI)
FBgn0265082(FlyBase)	AE014297(EMBL)
FBpp0307781(Ensembl_PRO)	ABW08601(EMBL-CDS)
40608(GeneID)	A8JQT5(Synonym)
FBtr0336812(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	FERM DOMAIN CONTAINING PROTEIN (PTHR45858)
PANTHER Subfamily:	MOESIN_EZRIN_RADIXIN HOMOLOG 1 (PTHR45858:SF5)
PANTHER GO-slim Molecular Function:	guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, guanyl-nucleotide exchange factor activity, cytoskeletal protein binding
GO BP Complete:	Rac protein signal transduction
GO CC Complete:	cytoskeleton, cellular_component

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by Rho GTPases, Axon guidance, Signal Transduction, Developmental Biology, Nervous system development, RHOF GTPase cycle, RHO GTPase cycle, SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion, RAC1 GTPase cycle, Semaphorin interactions, CDC42 GTPase cycle, RHOA GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3591\|UniProtKB=Q9Y4F1	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005985.7\|UniProtKB=H2Q7Q9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004930.3\|UniProtKB=G3QQG8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000009890.4\|UniProtKB=G7NJI7	Macaca mulatta	O
MOUSE\|MGI=MGI=2446173\|UniProtKB=F8VPU2	Mus musculus	O
RAT\|RGD=1305346\|UniProtKB=F1LYQ8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000146.6\|UniProtKB=F1MFC6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000026863.4\|UniProtKB=A0A5G2QPS5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015331.4\|UniProtKB=F6V541	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000014842.6\|UniProtKB=M3WLG1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020120.1\|UniProtKB=A0A8I3P0R0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008474.4\|UniProtKB=F7GEK9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005461.4\|UniProtKB=A0A6I8N8N1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010005991.1\|UniProtKB=A0A8V0XWJ1	Gallus gallus	O
CHICK\|Gene=FARP1\|UniProtKB=F1P065	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000016396.4\|UniProtKB=A0A803T9P3	Anolis carolinensis	O
XENLA\|Gene=LOC108709752\|UniProtKB=A0A8J0UJY8	Xenopus laevis	O
XENLA\|Gene=LOC108708478\|UniProtKB=A0A8J1MBA1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486840\|UniProtKB=A0A8J0QN80	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006374.2\|UniProtKB=H2LPM2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000017665.2\|UniProtKB=A0A3B3IFM9	Oryzias latipes	O
DANRE\|Gene=LOC101883674\|UniProtKB=A0A8M2BKB1	Danio rerio	O
DANRE\|Gene=farp1\|UniProtKB=A0A8M6Z6P5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003520.1\|UniProtKB=W5M732	lepisosteus oculatus	O
HUMAN\|HGNC=8079\|UniProtKB=Q6ZUT3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000022278.4\|UniProtKB=A0A2I3SN54	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000003479.4\|UniProtKB=F6TS31	Macaca mulatta	O
MOUSE\|MGI=MGI=2686379\|UniProtKB=A2AD83	Mus musculus	O
RAT\|RGD=1562057\|UniProtKB=F1M1Y3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007344.6\|UniProtKB=F1MX99	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000017988.4\|UniProtKB=A0A5F5PK62	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000029922.4\|UniProtKB=M3XAS9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845031084.1\|UniProtKB=A0A8I3QDS8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000015320.3\|UniProtKB=A0A5F8G6E0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000011700.2\|UniProtKB=F7A0V8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010017215.1\|UniProtKB=A0A8V0Z1J8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014721.3\|UniProtKB=H9GLF8	Anolis carolinensis	O
XENLA\|Gene=frmd7.L\|UniProtKB=A0A8J0TH51	Xenopus laevis	O
XENLA\|Gene=frmd7.S\|UniProtKB=A0A1L8F397	Xenopus laevis	O
XENTR\|Gene=frmd7\|UniProtKB=A0A8J0T3H4	Xenopus tropicalis	O
DANRE\|Gene=LOC557811\|UniProtKB=A0A8M9PJK0	Danio rerio	O
DANRE\|Gene=frmd7\|UniProtKB=A0A8M2BL62	Danio rerio	O
HUMAN\|HGNC=16460\|UniProtKB=O94887	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013123.5\|UniProtKB=K7B3S8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004259.3\|UniProtKB=G3QNR0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001313.4\|UniProtKB=F7BN41	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2385126\|UniProtKB=Q91VS8	Mus musculus	LDO
RAT\|RGD=1308003\|UniProtKB=D3ZFK8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013110.6\|UniProtKB=F1MSF0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016368.5\|UniProtKB=A0A287BRV9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008144.4\|UniProtKB=A0A9L0T4U2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002801.6\|UniProtKB=M3VZ58	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023180.1\|UniProtKB=A0A8I3PE45	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016044.4\|UniProtKB=F6YUJ6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011757.3\|UniProtKB=F6T102	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023388.1\|UniProtKB=A0A8V1A0K6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001192.4\|UniProtKB=G1K9D3	Anolis carolinensis	LDO
XENLA\|Gene=farp2.L\|UniProtKB=A0A8J1KU20	Xenopus laevis	LDO
XENTR\|Gene=farp2\|UniProtKB=A0A8J1JL42	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002154.2\|UniProtKB=A0A3B3H2I2	Oryzias latipes	LDO
DANRE\|Gene=farp2\|UniProtKB=A0A8M3ATD1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006339.1\|UniProtKB=W5MH07	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005613.3\|UniProtKB=F7AT12	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428211\|UniProtKB=A0A9J7N984	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579053\|UniProtKB=A0A7M7NKN1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001490\|UniProtKB=O17905	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG17296\|UniProtKB=A8XQS3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00102719\|UniProtKB=A0A2A6B4U9	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP001287\|UniProtKB=A0A1S4GBL6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013716\|UniProtKB=D6WK31	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_314509\|UniProtKB=E9G6D9	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023625\|UniProtKB=B7QIL1	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216385\|UniProtKB=A7SRN5	Nematostella vectensis	LDO