PANTHER Gene Information

Gene Symbol(s):

NFAT

Organism:

Drosophila melanogaster

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Gene Name:

NFAT nuclear factor, isoform B

Gene ID:

FBgn0030505

Protein ID:

A8JUV3

Persistent Id:

PTN000283440

Alternate Ids:

32321(GeneID)	NP_001096974(refSeq)
FBpp0111893(Ensembl_PRO)	FBgn0030505(FlyBase)
A8JUV3(Synonym)	FBtr0112980(Ensembl_TRS)
ABW09408(EMBL-CDS)	AE014298(EMBL)
158031811(GI)	FBgn0030505(Ensembl)
A8JUV3_DROME(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NFAT (PTHR12533)
PANTHER Subfamily:	NFAT NUCLEAR FACTOR, ISOFORM B (PTHR12533:SF7)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific transcription factor binding RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	transcription regulator complex
PANTHER protein class:	Rel homology transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription factor binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	response to salt stress, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, negative regulation of synaptic vesicle exocytosis
GO CC Complete:	transcription regulator complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by WNT, FCERI mediated Ca+2 mobilization, Fc epsilon receptor (FCERI) signaling, Ca2+ pathway, Signal Transduction, Immune System, Adaptive Immune System, Downstream signaling events of B Cell Receptor (BCR), C-type lectin receptors (CLRs), Signaling by the B Cell Receptor (BCR), Beta-catenin independent WNT signaling, Innate Immune System, Calcineurin activates NFAT, CLEC7A (Dectin-1) signaling, CLEC7A (Dectin-1) induces NFAT activation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7777\|UniProtKB=Q12968	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000008260.6\|UniProtKB=K7DDW5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010145.3\|UniProtKB=G3R3R8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000021843.4\|UniProtKB=F7EIB3	Macaca mulatta	O
MOUSE\|MGI=MGI=103296\|UniProtKB=P97305	Mus musculus	O
RAT\|RGD=1308692\|UniProtKB=A0A0G2JTY4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004368.6\|UniProtKB=F1MSU2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000029578.4\|UniProtKB=A0A287B5I3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014089.4\|UniProtKB=A0A3Q2HAK2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000030997.4\|UniProtKB=M3X7E0	Felis catus	O
MONDO\|Ensembl=ENSMODG00000005276.3\|UniProtKB=A0A5F8G5Z7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000021344.3\|UniProtKB=F6S104	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021335.1\|UniProtKB=A0A1D5P8S9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009839.4\|UniProtKB=H9GFR3	Anolis carolinensis	O
XENLA\|Gene=nfatc3.L\|UniProtKB=A0A1L8GK58	Xenopus laevis	O
XENLA\|Gene=nfatc3.S\|UniProtKB=Q8QHM1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-493918\|UniProtKB=B4F6V2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000027634.1\|UniProtKB=A0A3B3HZY7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000011964.2\|UniProtKB=H2M909	Oryzias latipes	O
DANRE\|Gene=nfatc3b\|UniProtKB=A0A8M3APB5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041111-41\|UniProtKB=E7FE12	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000008087.1\|UniProtKB=W5MN63	lepisosteus oculatus	O
HUMAN\|HGNC=7776\|UniProtKB=Q13469	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013628.6\|UniProtKB=H2R4F5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024518.2\|UniProtKB=A0A2I2Z5M1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000012657.4\|UniProtKB=A0A1D5QLW3	Macaca mulatta	O
MOUSE\|MGI=MGI=102463\|UniProtKB=Q60591	Mus musculus	O
RAT\|RGD=1307690\|UniProtKB=D4A0I8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000018270.6\|UniProtKB=F1MGR9	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007477.6\|UniProtKB=A5GFS6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000018997.4\|UniProtKB=A0A3Q2GY86	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000947.6\|UniProtKB=A0A337SIS5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026966.1\|UniProtKB=A0A8I3PTE6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016363.4\|UniProtKB=A0A5F8GT26	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008671.3\|UniProtKB=A0A6I8NPB1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010014143.1\|UniProtKB=E1C473	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013075.4\|UniProtKB=A0A803TMM2	Anolis carolinensis	O
XENLA\|Gene=nfatc2.S\|UniProtKB=A0A8J0U0C0	Xenopus laevis	O
XENLA\|Gene=nfatc2.L\|UniProtKB=A0A8J1LSR4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-492278\|UniProtKB=A0A8J0QIL1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000023353.1\|UniProtKB=A0A3B3HBY2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016173.2\|UniProtKB=H2MND3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-120913-5\|UniProtKB=E7F069	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-120913-4\|UniProtKB=E7F9Z5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002372.1\|UniProtKB=W5M323	lepisosteus oculatus	O
HUMAN\|HGNC=7775\|UniProtKB=O95644	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010129.5\|UniProtKB=A0A2I3RLV4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000006879.3\|UniProtKB=A0A2I2ZWX0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022596.4\|UniProtKB=A0A5F8ATU2	Macaca mulatta	O
MOUSE\|MGI=MGI=102469\|UniProtKB=O88942	Mus musculus	O
RAT\|RGD=2319357\|UniProtKB=D3ZE20	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000656.6\|UniProtKB=G3XCF6	Bos taurus	O
BOVIN\|Gene=NFATC1\|UniProtKB=P98201	Bos taurus	O
PIG\|Gene=NFATC1\|UniProtKB=O77638	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000004856.5\|UniProtKB=A0A287AA82	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000000884.6\|UniProtKB=A0A5F5XKD9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845000073.1\|UniProtKB=A0A8I3MEU0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012018.4\|UniProtKB=A0A5F8GI94	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000030248.2\|UniProtKB=A0A6I8PFM4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010007252.1\|UniProtKB=A0A8V0XX53	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000941.4\|UniProtKB=A0A803TKT5	Anolis carolinensis	O
XENLA\|Gene=nfatc1.L\|UniProtKB=A0A8J0VIM0	Xenopus laevis	O
XENLA\|Gene=nfatc1.S\|UniProtKB=A0A1L8FSH1	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000008055.2\|UniProtKB=H2LVH0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000020716.2\|UniProtKB=H2N2H2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-677\|UniProtKB=Q19AW4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007875.1\|UniProtKB=W5MMH0	lepisosteus oculatus	O
HUMAN\|HGNC=7778\|UniProtKB=Q14934	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000006218.5\|UniProtKB=K7DGW1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008797.3\|UniProtKB=G3R0B7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003370.4\|UniProtKB=F7E8G2	Macaca mulatta	O
MOUSE\|MGI=MGI=1920431\|UniProtKB=Q8K120	Mus musculus	O
RAT\|RGD=1310749\|UniProtKB=D3Z9H7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000006366.6\|UniProtKB=F1N106	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000001986.5\|UniProtKB=F1SGQ7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010992.4\|UniProtKB=A0A3Q2GZT8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005602.5\|UniProtKB=A0A337SQ18	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845007675.1\|UniProtKB=A0A8I3N7C4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000002992.4\|UniProtKB=F6Q4C9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046236.1\|UniProtKB=A0A6I8MZF0	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000009230.4\|UniProtKB=H9GF11	Anolis carolinensis	O
XENLA\|Gene=nfatc4.S\|UniProtKB=A0A8J0U9Q7	Xenopus laevis	O
XENLA\|Gene=nfatc4.L\|UniProtKB=A0A1L8HZL8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-876539\|UniProtKB=F6U5L6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000002953.2\|UniProtKB=H2LCP7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070912-659\|UniProtKB=E7F059	Danio rerio	O
HUMAN\|HGNC=7774\|UniProtKB=O94916	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008283.6\|UniProtKB=K7DKR3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006817.3\|UniProtKB=G3RPQ3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018255.4\|UniProtKB=F7DZJ9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1859333\|UniProtKB=Q9WV30	Mus musculus	LDO
RAT\|RGD=1309142\|UniProtKB=D3ZGB1	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000002755.6\|UniProtKB=K7GN13	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010266.4\|UniProtKB=A0A3Q2GVT3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002956.5\|UniProtKB=M3VZG8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845009257.1\|UniProtKB=A0A8I3N1Z0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002743.4\|UniProtKB=A0A5F8GEI3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002367.4\|UniProtKB=F6TLS9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008274.1\|UniProtKB=A0A8V0Y5J9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003530.4\|UniProtKB=H9G7U4	Anolis carolinensis	LDO
XENLA\|Gene=nfat5.S\|UniProtKB=A0A8J0V1V0	Xenopus laevis	O
XENLA\|Gene=nfat5.L\|UniProtKB=A0A8J0V185	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6069990\|UniProtKB=A0A6I8R1E5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010349.2\|UniProtKB=H2M3G1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007600.2\|UniProtKB=H2LTV6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-6322\|UniProtKB=Q6PD88	Danio rerio	O
DANRE\|Gene=nfat5b\|UniProtKB=A0A8M9PQA8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003985.1\|UniProtKB=W5M8Q2	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118418168\|UniProtKB=A0A9J7LBQ8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC590859\|UniProtKB=A0A7M7LTI6	Strongylocentrotus purpuratus	LDO
ANOGA\|EnsemblGenome=AGAP013287\|UniProtKB=A0A453YYJ4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014708\|UniProtKB=D6WNZ3	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW023728\|UniProtKB=B7QHC8	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243338\|UniProtKB=A7S787	Nematostella vectensis	LDO