PANTHER Gene Information

Gene Symbol(s):

LEUTX

Organism:

Homo sapiens

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Gene Name:

Paired-like homeodomain transcription factor LEUTX

Gene ID:

HGNC:31953

Protein ID:

A8MZ59

Enhancers:

View enhancers for HUMAN|HGNC=31953|UniProtKB=A8MZ59

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN008165047

Alternate Ids:

LEUTX_HUMAN(UniProtKB-ID)	119577319(GI)
ENSG00000280774(Ensembl)	A0A1W2PQ33(AltAccession)
LEUTX{ECO:0000312\|HGNC:HGNC:31953}(Symbol)	AC005393(EMBL)
618701(MIM)	PRD-LIKE homeobox transcription factor LEUTX {ECO:0000303\|PubMed:27578796}(Synonym)
342900(GeneID)	HGNC:31953(HGNC)
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PANTHER Classification

PANTHER Family:	HOMEOBOX PROTEIN (PTHR45793)
PANTHER Subfamily:	PAIRED-LIKE HOMEODOMAIN TRANSCRIPTION FACTOR LEUTX (PTHR45793:SF18)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, chromatin, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Maternal to zygotic transition (MZT), Developmental Biology, Zygotic genome activation (ZGA)

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000033892.3\|UniProtKB=A0A2I3T614	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000027834.2\|UniProtKB=A0A2I2ZWG8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000042532.2\|UniProtKB=A0A1D5QB23	Macaca mulatta	LDO
BOVIN\|Ensembl=ENSBTAG00000046425.2\|UniProtKB=G3MWG9	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000033778.2\|UniProtKB=A0A9L0TMT0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000033458.3\|UniProtKB=A0A3Q2I670	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000048918.1\|UniProtKB=A0A5F5XY94	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000047238.1\|UniProtKB=A0A5F8GF02	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000036512.1\|UniProtKB=A0A6I8PP01	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00015006068\|UniProtKB=O73592	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010008261.1\|UniProtKB=A0A8V0Y1P1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000011257.4\|UniProtKB=H9GHD5	Anolis carolinensis	O
XENLA\|Gene=crx.S\|UniProtKB=A0A1L8F3X7	Xenopus laevis	O
XENLA\|Gene=otx5-a\|UniProtKB=Q9PVM0	Xenopus laevis	O
XENLA\|Gene=otx5-b\|UniProtKB=Q9PT61	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-478452\|UniProtKB=Q28EM7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000008681.2\|UniProtKB=H2LXM9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-010403-1\|UniProtKB=Q8JIZ3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030508-1\|UniProtKB=Q6NYT9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014175.1\|UniProtKB=W5NA00	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000019349.1\|UniProtKB=Q4H303	Ciona intestinalis	O
BRAFL\|Gene=LOC118420234\|UniProtKB=A0A9J7LI20	Branchiostoma floridae	O
STRPU\|Gene=OTX\|UniProtKB=Q26417	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105440739\|UniProtKB=A0A7M7PBY7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918809\|UniProtKB=A0A7M7P6Y3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_373400\|UniProtKB=A0A7M6UHL8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00000457\|UniProtKB=Q93352	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16311\|UniProtKB=A8XNP9	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00000458\|UniProtKB=Q93356	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16312\|UniProtKB=A8XNP8	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00006652\|UniProtKB=Q9U2Z0	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16288\|UniProtKB=A8XNQ8	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00033797\|UniProtKB=A8XGQ3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00116854\|UniProtKB=A0A2A6D035	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116855\|UniProtKB=A0A454Y2F5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116852\|UniProtKB=A0A454XNC7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116268\|UniProtKB=A0A8R1YKT2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0004102\|UniProtKB=P22810	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000215\|UniProtKB=A0A1S4G861	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003354\|UniProtKB=O46169	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC003355\|UniProtKB=A0A139WLT5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347230\|UniProtKB=E9G1B9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347231\|UniProtKB=E9G1B8	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG70729\|UniProtKB=T1G0B3	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213735\|UniProtKB=A7SKM4	Nematostella vectensis	O
USTMA\|EnsemblGenome=UMAG_12332\|UniProtKB=A0A0D1CA32	Ustilago maydis	O