PANTHER Gene Information   
Gene Symbol(s): Anapc10
Organism: Rattus norvegicus
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Gene Name: Anaphase-promoting complex subunit 10
Gene ID: 1308936
Protein ID: B5DEP3
Persistent Id: PTN000309740
Alternate Ids:
1308936(RGD) ENSRNOG00000018296(Ensembl)
B5DEP3(Synonym) ENSRNOT00000024689(Ensembl_TRS)
NM_001108445(refSeq) 361389(GeneID)
ENSRNOP00000024689(Ensembl_PRO) 564395321(GI)
B5DEP3_RAT(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: ANAPHASE-PROMOTING COMPLEX 10 (PTHR12936)
PANTHER Subfamily: ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 (PTHR12936:SF0)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: protein K11-linked ubiquitination
PANTHER GO-slim Cellular Component: anaphase-promoting complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: Cell cycle
   APC
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: -
GO BP Complete: cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, anaphase-promoting complex-dependent catabolic process
GO CC Complete: cytoplasm, anaphase-promoting complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DNA Replication Pre-Initiation, Cellular Senescence, Cellular responses to stress, S Phase, Senescence-Associated Secretory Phenotype (SASP), Cell Cycle Checkpoints, Cellular responses to stimuli, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, Separation of Sister Chromatids, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, APC/C:Cdc20 mediated degradation of Cyclin B, Assembly of the pre-replicative complex, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Synthesis of DNA, APC/C-mediated degradation of cell cycle proteins, Mitotic Spindle Checkpoint, Autodegradation of Cdh1 by Cdh1:APC/C, Cell Cycle, Mitotic, Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Mitotic Anaphase, Cell Cycle, M Phase, CDK-mediated phosphorylation and removal of Cdc6, Mitotic Metaphase and Anaphase, Regulation of APC/C activators between G1/S and early anaphase, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase, Switching of origins to a post-replicative state, APC/C:Cdc20 mediated degradation of mitotic proteins, APC-Cdc20 mediated degradation of Nek2A, Class I MHC mediated antigen processing & presentation, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Phosphorylation of the APC/C, Inactivation of APC/C via direct inhibition of the APC/C complex, Regulation of mitotic cell cycle, DNA Replication, APC/C:Cdc20 mediated degradation of Securin, Adaptive Immune System

Orthologs