PANTHER Gene Information   
Gene Symbol(s): Dusp10
Organism: Rattus norvegicus
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Gene Name: Dual specificity phosphatase 10
Gene ID: 1310844
Protein ID: D3ZBG7
Persistent Id: PTN000017155
Alternate Ids:
1310844(RGD) ENSRNOG00000004003(Ensembl)
D3ZBG7(Synonym) ENSRNOT00000005400(Ensembl_TRS)
NP_001099204(refSeq) 157787135(GI)
ENSRNOP00000005400(Ensembl_PRO) 63995(GeneID)
D3ZBG7_RAT(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: DUAL SPECIFICITY PROTEIN PHOSPHATASE (PTHR10159)
PANTHER Subfamily: DUAL SPECIFICITY PROTEIN PHOSPHATASE 10 (PTHR10159:SF299)  
PANTHER GO-slim Molecular Function: protein tyrosine phosphatase activity
PANTHER GO-slim Biological Process: negative regulation of protein kinase activity
regulation of MAP kinase activity
peptidyl-tyrosine dephosphorylation
negative regulation of MAPK cascade
regulation of JNK cascade
PANTHER GO-slim Cellular Component: cytosol
PANTHER protein class: protein phosphatase
Pathway Categories: Oxidative stress response
   Mitogen activated protein kinase phosphatase 5
p38 MAPK pathway
   Mitogen activated protein kinase phosphatase 5
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: MAP kinase phosphatase activity, mitogen-activated protein kinase p38 binding, protein tyrosine/threonine phosphatase activity, MAP kinase tyrosine phosphatase activity, phosphatase activity, JUN kinase binding, MAP kinase tyrosine/serine/threonine phosphatase activity, myosin phosphatase activity
GO BP Complete: oligodendrocyte differentiation, negative regulation of respiratory burst involved in inflammatory response, regulation of brown fat cell differentiation, negative regulation of JUN kinase activity, negative regulation of p38MAPK cascade, negative regulation of JNK cascade, negative regulation of oligodendrocyte differentiation, positive regulation of regulatory T cell differentiation, negative regulation of ERK1 and ERK2 cascade, regulation of innate immune response, negative regulation of epithelial cell proliferation, negative regulation of epithelial cell migration, negative regulation of stress-activated MAPK cascade, response to lipopolysaccharide, regulation of adaptive immune response, negative regulation of epithelium regeneration, peptidyl-tyrosine dephosphorylation, stress-activated MAPK cascade
GO CC Complete: nucleus, cytoplasm, cytosol, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: MAPK1/MAPK3 signaling, MAPK family signaling cascades, RAF-independent MAPK1/3 activation, Signal Transduction, RAF/MAP kinase cascade, Negative regulation of MAPK pathway

Orthologs