PANTHER Gene Information

Gene Symbol(s):

Map3k6

Organism:

Rattus norvegicus

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Gene Name:

mitogen-activated protein kinase kinase kinase

Gene ID:

1304625

Protein ID:

D3ZFL3

Persistent Id:

PTN000684882

Alternate Ids:

NP_001101379(refSeq)	D3ZFL3(Synonym)
ENSRNOG00000008936(Ensembl)	ENSRNOT00000012463(Ensembl_TRS)
1304625(RGD)	157816917(GI)
313022(GeneID)	ENSRNOP00000012463(Ensembl_PRO)
D3ZFL3_RAT(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE PROTEIN KINASE (PTHR11584)
PANTHER Subfamily:	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6 (PTHR11584:SF391)
PANTHER GO-slim Molecular Function:	MAP kinase kinase kinase activity
PANTHER GO-slim Biological Process:	cellular response to stress
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

FGF signaling pathway

Mitogen-activated protein kinase kinase kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase kinase activity
GO BP Complete:	p38MAPK cascade, JNK cascade, protein phosphorylation
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6858\|UniProtKB=O95382	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000404.6\|UniProtKB=H2PYF3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000045.3\|UniProtKB=G3QCU7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018318.4\|UniProtKB=F7HFE8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1855691\|UniProtKB=Q9WTR2	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000010254.5\|UniProtKB=E1BBJ8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003573.6\|UniProtKB=K7GLX4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015410.4\|UniProtKB=A0A5F5PLK7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000007864.6\|UniProtKB=M3W8J0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010722.1\|UniProtKB=A0A8I3NBA4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014479.4\|UniProtKB=F6ZG40	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040771.1\|UniProtKB=A0A6I8N6G2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016816.1\|UniProtKB=A0A8V0YZK0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017835.4\|UniProtKB=H9GPS4	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000014582.2\|UniProtKB=H2MI14	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-8638\|UniProtKB=A0A2R8QB27	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002899.1\|UniProtKB=W5M4W8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118423067\|UniProtKB=A0A9J7LQP1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592507\|UniProtKB=A0A7M7PG68	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003822\|UniProtKB=Q21029	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG02299\|UniProtKB=A8WUN1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00102966\|UniProtKB=A0A2A6CXE4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0014006\|UniProtKB=Q9VDS9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000747\|UniProtKB=A0A1S4G9T3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000430\|UniProtKB=A0A139WMY0	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW002207\|UniProtKB=B7P9M0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG189913\|UniProtKB=T1FRH3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG62517\|UniProtKB=T1FX18	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG10277\|UniProtKB=B3RYN2	Trichoplax adhaerens	LDO
YEAST\|SGD=S000004354\|UniProtKB=P23561	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL011C\|UniProtKB=Q75DM8	Eremothecium gossypii	O
CANAL\|CGD=CAL0000193264\|UniProtKB=A0A1D8PGY4	Candida albicans	O
SCHPO\|PomBase=SPBC1D7.05\|UniProtKB=P28829	Schizosaccharomyces pombe	O
BATDJ\|Gene_ORFName=BATDEDRAFT_8175\|UniProtKB=F4NS44	Batrachochytrium dendrobatidis	O
DICPU\|EnsemblGenome=DICPUDRAFT_160010\|UniProtKB=F1A5H4	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_155882\|UniProtKB=F0ZV50	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38722\|UniProtKB=F0ZV52	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_160009\|UniProtKB=F1A5H3	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_27_1370\|UniProtKB=E9ADB8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.5650\|UniProtKB=Q382D0	Trypanosoma brucei	O
PARTE\|EnsemblGenome=GSPATT00024080001\|UniProtKB=A0E7T5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025835001\|UniProtKB=A0EDX4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028305001\|UniProtKB=A0BFF3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021532001\|UniProtKB=A0DXZ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022805001\|UniProtKB=A0E2W6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007651001\|UniProtKB=A0CI99	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026498001\|UniProtKB=A0EFT4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032618001\|UniProtKB=A0BW49	Paramecium tetraurelia	O
CHLRE\|EnsemblGenome=CHLRE_10g464100v5\|UniProtKB=A0A2K3DC36	Chlamydomonas reinhardtii	O
MAIZE\|EnsemblGenome=Zm00001eb099000\|UniProtKB=A0A1D6EPI1	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0478260\|UniProtKB=A0A8I7B904	Hordeum vulgare subsp. vulgare	O
HELAN\|Gene_ORFName=HanXRQr2_Chr10g0457601\|UniProtKB=A0A9K3I0S3	Helianthus annuus	O
SELML\|EnsemblGenome=SELMODRAFT_139837\|UniProtKB=D8QMU8	Selaginella moellendorffii	O