Gene Symbol(s):
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Tradd
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Organism: |
Rattus norvegicus |
View Gene in Tree |
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Gene Name: |
Tumor necrosis factor receptor type 1-associated DEATH domain protein
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Gene ID: |
621313
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Protein ID: |
D3ZZC5
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Persistent Id: |
PTN000793848 |
Alternate Ids: |
621313(RGD) |
ENSRNOP00000020405(Ensembl_PRO) |
ENSRNOT00000020405(Ensembl_TRS) |
D3ZZC5(Synonym) |
281427214(GI) |
ENSRNOG00000015179(Ensembl) |
D3ZZC5_RAT(UniProtKB-ID) |
XP_006255506(refSeq) |
246756(GeneID) |
Show All
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GO MF Complete: |
identical protein binding, protein binding, signaling adaptor activity, tumor necrosis factor receptor binding, transmembrane receptor protein tyrosine kinase adaptor activity, protein-macromolecule adaptor activity, kinase binding, death domain binding, protein-containing complex binding
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GO BP Complete: |
tumor necrosis factor-mediated signaling pathway, TRAIL-activated apoptotic signaling pathway, positive regulation of inflammatory response, positive regulation of canonical NF-kappaB signal transduction, extrinsic apoptotic signaling pathway, cell surface receptor protein tyrosine kinase signaling pathway, cellular response to tumor necrosis factor, canonical NF-kappaB signal transduction, positive regulation of hair follicle development, positive regulation of cell migration
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GO CC Complete: |
nucleus, cytoskeleton, cytoplasm, tumor necrosis factor receptor superfamily complex, protein-containing complex, receptor complex, plasma membrane
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Reactome Pathways: |
Death Receptor Signaling, Apoptosis, Signal Transduction, Regulation of necroptotic cell death, Regulation by c-FLIP, CASP8 activity is inhibited, Regulated Necrosis, Regulation of TNFR1 signaling, RIPK1-mediated regulated necrosis, TNF signaling, Caspase activation via extrinsic apoptotic signalling pathway, TNFR1-induced NF-kappa-B signaling pathway, Programmed Cell Death, Dimerization of procaspase-8, TNFR1-induced proapoptotic signaling, Caspase activation via Death Receptors in the presence of ligand
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