PANTHER Gene Information   
Gene Symbol(s): Tradd
Organism: Rattus norvegicus
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Gene Name: Tumor necrosis factor receptor type 1-associated DEATH domain protein
Gene ID: 621313
Protein ID: D3ZZC5
Persistent Id: PTN000793848
Alternate Ids:
621313(RGD) ENSRNOP00000020405(Ensembl_PRO)
ENSRNOT00000020405(Ensembl_TRS) D3ZZC5(Synonym)
281427214(GI) ENSRNOG00000015179(Ensembl)
D3ZZC5_RAT(UniProtKB-ID) XP_006255506(refSeq)
246756(GeneID)
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PANTHER Classification
PANTHER Family: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN (PTHR14913)
PANTHER Subfamily: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN (PTHR14913:SF0)  
PANTHER GO-slim Molecular Function: receptor tyrosine kinase binding
signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: extrinsic apoptotic signaling pathway
PANTHER GO-slim Cellular Component: receptor complex
PANTHER protein class:
Pathway Categories: Apoptosis signaling pathway
   TNFR1 associated death domain

GO MF Complete: identical protein binding, protein binding, signaling adaptor activity, tumor necrosis factor receptor binding, transmembrane receptor protein tyrosine kinase adaptor activity, protein-macromolecule adaptor activity, kinase binding, death domain binding, protein-containing complex binding
GO BP Complete: tumor necrosis factor-mediated signaling pathway, TRAIL-activated apoptotic signaling pathway, positive regulation of inflammatory response, positive regulation of canonical NF-kappaB signal transduction, extrinsic apoptotic signaling pathway, cell surface receptor protein tyrosine kinase signaling pathway, cellular response to tumor necrosis factor, canonical NF-kappaB signal transduction, positive regulation of hair follicle development, positive regulation of cell migration
GO CC Complete: nucleus, cytoskeleton, cytoplasm, tumor necrosis factor receptor superfamily complex, protein-containing complex, receptor complex, plasma membrane
Reactome Pathways: Death Receptor Signaling, Apoptosis, Signal Transduction, Regulation of necroptotic cell death, Regulation by c-FLIP, CASP8 activity is inhibited, Regulated Necrosis, Regulation of TNFR1 signaling, RIPK1-mediated regulated necrosis, TNF signaling, Caspase activation via extrinsic apoptotic signalling pathway, TNFR1-induced NF-kappa-B signaling pathway, Programmed Cell Death, Dimerization of procaspase-8, TNFR1-induced proapoptotic signaling, Caspase activation via Death Receptors in the presence of ligand