PANTHER Gene Information   
Gene Symbol(s): Foxo4
Organism: Rattus norvegicus
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Gene Name: Forkhead box O4
Gene ID: 1561201
Protein ID: D4A433
Persistent Id: PTN000215207
Alternate Ids:
302415(GeneID) XM_017601967(refSeq)
1561201(RGD) D4A433_RAT(UniProtKB-ID)
ENSRNOG00000033316(Ensembl) ENSRNOP00000042383(Ensembl_PRO)
ENSRNOT00000048521(Ensembl_TRS) D4A433(Synonym)
1046907103(GI)
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PANTHER Classification
PANTHER Family: FORKHEAD BOX PROTEIN O (PTHR45767)
PANTHER Subfamily: FORKHEAD BOX PROTEIN O4 (PTHR45767:SF3)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: winged helix/forkhead transcription factor
Pathway Categories: PI3 kinase pathway
   FOXO

GO MF Complete: identical protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, beta-catenin binding, DNA-binding transcription factor activity, RNA polymerase II-specific, nucleic acid binding, DNA binding, DNA-binding transcription factor activity, protein binding, promoter-specific chromatin binding, sequence-specific double-stranded DNA binding, DNA-binding transcription factor binding, enzyme binding
GO BP Complete: mitotic G2 DNA damage checkpoint signaling, negative regulation of angiogenesis, insulin receptor signaling pathway, negative regulation of cell population proliferation, regulation of DNA-templated transcription, negative regulation of smooth muscle cell differentiation, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II, response to oxidative stress, response to water-immersion restraint stress, stem cell differentiation, positive regulation of DNA-templated transcription, positive regulation of smooth muscle cell migration, negative regulation of G0 to G1 transition, response to nutrient levels
GO CC Complete: nucleus, cytoplasm, nuclear speck, cytosol, nucleoplasm
Reactome Pathways: FOXO-mediated transcription, Regulation of localization of FOXO transcription factors, Deubiquitination, Signal Transduction, Metabolism of proteins, PIP3 activates AKT signaling, Post-translational protein modification, RNA Polymerase II Transcription, Generic Transcription Pathway, Intracellular signaling by second messengers, FOXO-mediated transcription of cell cycle genes, FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes, Gene expression (Transcription), AKT phosphorylates targets in the nucleus, Ub-specific processing proteases