PANTHER Gene Information

Gene Symbol(s):

uhrf1

Organism:

Danio rerio

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Gene Name:

E3 ubiquitin-protein ligase UHRF1

Gene ID:

ZDB-GENE-040426-2039

Protein ID:

E7EZF3

Persistent Id:

PTN000365198

Alternate Ids:

BX927276(EMBL)	UHRF1_DANRE(UniProtKB-ID)
Ubiquitin-like PHD and RING finger domain-containing protein 1(Synonym)	uhrf1(Symbol)
406350(GeneID)	ZDB-GENE-040426-2039(ZFIN)
34783763(GI)	AAH58055(EMBL-CDS)
NM_213077(refSeq)	2.3.2.27(EC)
Q6PEI0(AltAccession)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED (PTHR14140)
PANTHER Subfamily:	E3 UBIQUITIN-PROTEIN LIGASE UHRF1 (PTHR14140:SF2)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein ubiquitination negative regulation of gene expression, epigenetic
PANTHER GO-slim Cellular Component:
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, ubiquitin-protein transferase activity, zinc ion binding, ubiquitin protein ligase activity, hemi-methylated DNA-binding, metal ion binding, methylated histone binding, transferase activity
GO BP Complete:	negative regulation of transcription by RNA polymerase II, inflammatory response, liver development, heterochromatin formation, intestinal epithelial structure maintenance, negative regulation of gene expression via chromosomal CpG island methylation, animal organ regeneration, lens development in camera-type eye, chromatin organization, ubiquitin-dependent protein catabolic process, protein ubiquitination
GO CC Complete:	replication fork, heterochromatin, nucleus, euchromatin, cytoplasm, chromatin

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12556\|UniProtKB=Q96T88	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010326.6\|UniProtKB=H2QF26	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004610.3\|UniProtKB=G3RVG5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012705.4\|UniProtKB=F7DWN1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1338889\|UniProtKB=Q8VDF2	Mus musculus	LDO
RAT\|RGD=1595855\|UniProtKB=Q7TPK1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002224\|UniProtKB=A7E320	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013517.5\|UniProtKB=A0A287BKE5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013193.4\|UniProtKB=A0A3Q2KX83	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010146.6\|UniProtKB=M3WCS2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014196.1\|UniProtKB=A0A8I3NSN1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001108.3\|UniProtKB=F7DPG2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005332.3\|UniProtKB=F7BE55	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028528.1\|UniProtKB=A0A8V1AJ28	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008483.4\|UniProtKB=A0A803T7A9	Anolis carolinensis	LDO
XENLA\|Gene=uhrf1.S\|UniProtKB=A0A8J1LP39	Xenopus laevis	LDO
XENLA\|Gene=uhrf1\|UniProtKB=B6CHA3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5821474\|UniProtKB=F6UA42	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006710.2\|UniProtKB=H2LQT2	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000000097.1\|UniProtKB=W5LVF4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020404.1\|UniProtKB=H2XUH7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118431750\|UniProtKB=A0A9J7MF82	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586739\|UniProtKB=A0A7M7PJA1	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC034137\|UniProtKB=A0A139WCU0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001240\|UniProtKB=D6WAY6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_307368\|UniProtKB=E9H1Q4	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG79229\|UniProtKB=T1G3L5	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG113832\|UniProtKB=T1EFX2	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g226911\|UniProtKB=A7S739	Nematostella vectensis	LDO
NEUCR\|EnsemblGenome=NCU08123\|UniProtKB=Q7S4K8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_00062\|UniProtKB=A7E440	Sclerotinia sclerotiorum	O
PHANO\|Gene_ORFName=SNOG_11325\|UniProtKB=Q0UA89	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNA06550\|UniProtKB=Q5KNG7	Cryptococcus neoformans	O
PUCGT\|EnsemblGenome=PGTG_16207\|UniProtKB=E3L032	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_08386\|UniProtKB=E3KDJ4	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_12990\|UniProtKB=E3KQN3	Puccinia graminis	O
CHLRE\|EnsemblGenome=CHLRE_03g163850v5\|UniProtKB=A0A2K3DWL5	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00016p00085910\|UniProtKB=W1PGB3	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_2G00700\|UniProtKB=A0A0K9PAE2	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_2G00710\|UniProtKB=A0A0K9PAR5	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_11G00240\|UniProtKB=A0A0K9Q134	Zostera marina	O
MUSAM\|EnsemblGenome=Ma05_g18370\|UniProtKB=A0A804J5V6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g24050\|UniProtKB=A0A804JZ66	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g01060\|UniProtKB=A0A804KEL8	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_021319mg\|UniProtKB=K3Z451	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G101200\|UniProtKB=A0A1B6QAA2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb304730\|UniProtKB=A0A1D6HX03	Zea mays	O
SORBI\|EnsemblGenome=SORBI_3009G001200\|UniProtKB=C5YXY0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb267610\|UniProtKB=A0A1D6LIP4	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb356240\|UniProtKB=A0A804QV96	Zea mays	O
ORYSJ\|EnsemblGenome=Os05g0102600\|UniProtKB=A0A5S6R743	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g40000v3\|UniProtKB=I1HN90	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0000630\|UniProtKB=A0A8I7B1W5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1A02G005700\|UniProtKB=A0A3B5XT84	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G002400\|UniProtKB=A0A3B5ZM31	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G007900\|UniProtKB=A0A3B5YQ56	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_004726\|UniProtKB=A0A1U7ZGB6	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_009253\|UniProtKB=A0A1U7ZMM6	Nelumbo nucifera	O
SPIOL\|Gene=LOC110784608\|UniProtKB=A0A9R0JSA3	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0788481\|UniProtKB=A0A251RLY9	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300113980\|UniProtKB=A0A9R1W4T6	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0254491\|UniProtKB=A0A251UHF5	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0788471\|UniProtKB=A0A251RRK0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300113960\|UniProtKB=A0A9R1W6K8	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a002434mg\|UniProtKB=A0A022Q5J3	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a002386mg\|UniProtKB=A0A022QKM2	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_10671\|UniProtKB=A0A2G3A2V4	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_10670\|UniProtKB=A0A2G3A2V1	Capsicum annuum	O
TOBAC\|Gene=LOC107772885\|UniProtKB=A0A1S3Y779	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_27745\|UniProtKB=A0A1U8EKK5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400033921\|UniProtKB=M1D7Q6	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc05g023680.3\|UniProtKB=A0A3Q7GHS7	Solanum lycopersicum	O
TOBAC\|Gene=LOC107818035\|UniProtKB=A0A1S4CDY8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107784870\|UniProtKB=A0A1S3ZB23	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi01g01773\|UniProtKB=F6HJ69	Vitis vinifera	O
THECC\|EnsemblGenome=TCM_008331\|UniProtKB=A0A061E3K2	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_003G162400v3\|UniProtKB=A0A2K2B813	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G067700v3\|UniProtKB=A0A2K2BTH7	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_08G101100\|UniProtKB=A0A2C9VF22	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1499130\|UniProtKB=B9R9N9	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_1438390\|UniProtKB=B9RG02	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_14G003700\|UniProtKB=I1M660	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_02G309100\|UniProtKB=A0A0R0L450	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g114910\|UniProtKB=A0A072VDM7	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_5g098680\|UniProtKB=G7K0P6	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_8g102580\|UniProtKB=G7L7G5	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr16_14860\|UniProtKB=A0A2I4GCK1	Juglans regia	O
PRUPE\|EnsemblGenome=PRUPE_1G214700\|UniProtKB=A0A251R423	Prunus persica	O
EUCGR\|EnsemblGenome=EUGRSUZ_B03561\|UniProtKB=A0A059D9Y4	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00078185001\|UniProtKB=A0A078FL83	Brassica napus	O
BRACM\|EnsemblGenome=Bra038515\|UniProtKB=M4FBP9	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00025337001\|UniProtKB=A0A078J0V7	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00049628001\|UniProtKB=A0A078FAZ8	Brassica napus	O
BRACM\|EnsemblGenome=Bra007810\|UniProtKB=M4CUB6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00041564001\|UniProtKB=A0A078GQR9	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00124408001\|UniProtKB=A0A078F700	Brassica napus	O
BRACM\|EnsemblGenome=Bra004082\|UniProtKB=M4CIP8	Brassica campestris	O
ARATH\|TAIR=locus=2013800\|UniProtKB=Q9C8E1	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2138591\|UniProtKB=Q681I0	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2013840\|UniProtKB=Q680I0	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2164835\|UniProtKB=Q9FKA7	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2009425\|UniProtKB=Q9FVS2	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2009420\|UniProtKB=Q8VYZ0	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107946889\|UniProtKB=A0A1U8NCX6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_014765\|UniProtKB=A0A061G013	Theobroma cacao	O
GOSHI\|Gene=LOC107890846\|UniProtKB=A0A1U8HY24	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904672\|UniProtKB=A0A1U8J8D7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107899051\|UniProtKB=A0A1U8IPS1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924488\|UniProtKB=A0A1U8LAP8	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_012584\|UniProtKB=A0A061FUM9	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g004418mg\|UniProtKB=A0A067FHD9	Citrus sinensis	O
MANES\|EnsemblGenome=MANES_14G168600\|UniProtKB=A0A2C9UPB5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0571480\|UniProtKB=B9SU90	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_12G001300\|UniProtKB=I1LNN5	Glycine max	O
JUGRE\|EnsemblGenome=Jr09_00150\|UniProtKB=A0A2I4FYF5	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G507950\|UniProtKB=A0A0A0L3V5	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_5G140900\|UniProtKB=A0A251P888	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_51852\|UniProtKB=D8RRN1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_109372\|UniProtKB=D8S663	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_104036\|UniProtKB=D8RXI8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c10_16970\|UniProtKB=A0A2K1JZC6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c3_20850\|UniProtKB=A0A7I4FM51	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0002s0033\|UniProtKB=A0A2R6XTW0	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0005s0130\|UniProtKB=A0A2R6XQW1	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_009850020\|UniProtKB=A0A1Y1IN71	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000720060\|UniProtKB=A0A1Y1HX74	Klebsormidium nitens	O