PANTHER Gene Information

Gene Symbol(s):

Tcf7l1

Organism:

Rattus norvegicus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Transcription factor 7 like 1

Gene ID:

1311671

Protein ID:

F1M1R9

Persistent Id:

PTN001310337

Alternate Ids:

ENSRNOG00000014753(Ensembl)	NM_001107865(refSeq)
ENSRNOT00000020005(Ensembl_TRS)	F1M1R9(Synonym)
1311671(RGD)	ENSRNOP00000020005(Ensembl_PRO)
F1M1R9_RAT(UniProtKB-ID)
Show All

PANTHER Classification

PANTHER Family:	TRANSCRIPTION FACTOR 7 FAMILY MEMBER (PTHR10373)
PANTHER Subfamily:	TRANSCRIPTION FACTOR 7-LIKE 1 (PTHR10373:SF25)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II canonical Wnt signaling pathway
PANTHER GO-slim Cellular Component:	chromatin RNA polymerase II transcription regulator complex
PANTHER protein class:	DNA-binding transcription factor

Pathway Categories:

Wnt signaling pathway

Wnt Target Genes

Wnt signaling pathway

T-Cell Transcription Factor

Gonadotropin-releasing hormone receptor pathway

TCF

Cadherin signaling pathway

T-cell factor/lymphoid enhancer factor

Alzheimer disease-presenilin pathway

T-cell factor/lymphoid enhancer factor

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, chromatin binding, beta-catenin binding, sequence-specific double-stranded DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	regulation of somatic stem cell population maintenance, biological_process, anterior/posterior axis specification, embryo, transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase II, skin development, axial mesoderm morphogenesis, regulation of transcription by RNA polymerase II, negative regulation of DNA-templated transcription, stem cell differentiation, somatic stem cell population maintenance, regulation of stem cell population maintenance, canonical Wnt signaling pathway
GO CC Complete:	nucleus, cytosol, chromatin, nucleoplasm, beta-catenin-TCF complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11640\|UniProtKB=Q9HCS4	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000012128.5\|UniProtKB=H2QI87	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008549.3\|UniProtKB=G3QZP8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020134.4\|UniProtKB=F6U055	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1202876\|UniProtKB=Q9Z1J1	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000010111.7\|UniProtKB=F1MJS2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008241.5\|UniProtKB=A0A5G2Q9J1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022931.4\|UniProtKB=F6UFR6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003376.6\|UniProtKB=A0A2I2UXR6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014626.1\|UniProtKB=A0A8I3NXQ2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000015573.4\|UniProtKB=F7AIP6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040416.1\|UniProtKB=A0A6I8NXF6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020180.1\|UniProtKB=A0A8V0ZDN0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011398.4\|UniProtKB=H9GHN0	Anolis carolinensis	LDO
XENLA\|Gene=tcf7l1-d\|UniProtKB=P70064	Xenopus laevis	O
XENLA\|Gene=tcf7l1.S\|UniProtKB=A0A8J0UU95	Xenopus laevis	O
XENLA\|Gene=tcf7l1-c\|UniProtKB=P70063	Xenopus laevis	O
XENLA\|Gene=tcf7l1-b\|UniProtKB=Q90ZB6	Xenopus laevis	O
XENLA\|Gene=tcf7l1-a\|UniProtKB=P70062	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1031985\|UniProtKB=Q6GL68	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011813.2\|UniProtKB=H2M8J2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-991110-10\|UniProtKB=Q800Q5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980605-30\|UniProtKB=Q9YHE8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015067.1\|UniProtKB=W5ND38	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002003.3\|UniProtKB=F6WT98	Ciona intestinalis	O
BRAFL\|Gene=LOC118412533\|UniProtKB=A0A9J7ML77	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_373203\|UniProtKB=A0A7M7NGM2	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004077\|UniProtKB=Q10666	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10973\|UniProtKB=A8XBY9	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG16744\|UniProtKB=A8XPR0	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00032197\|UniProtKB=A8XBZ0	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG11789\|UniProtKB=A8XE20	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00042123\|UniProtKB=H8WH12	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00026953\|UniProtKB=A8WWH5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00099291\|UniProtKB=A0A2A6BV24	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278626\|UniProtKB=A0A8R1UTZ0	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0085432\|UniProtKB=Q8IMA8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP012411\|UniProtKB=A0A1S4HA50	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012389\|UniProtKB=A0A1S4H951	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC032496\|UniProtKB=A0A139WL58	Tribolium castaneum	O