PANTHER Gene Information

Gene Symbol(s):

Srgap1

Organism:

Rattus norvegicus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

SLIT-ROBO Rho GTPase activating protein 1

Gene ID:

1566260

Protein ID:

F1M287

Persistent Id:

PTN000366530

Alternate Ids:

ENSRNOP00000006180(Ensembl_PRO)	1566260(RGD)
NM_001191784(refSeq)	F1M287_RAT(UniProtKB-ID)
300796374(GI)	ENSRNOG00000004603(Ensembl)
ENSRNOT00000006180(Ensembl_TRS)	F1M287(Synonym)
314903(GeneID)
Show All

PANTHER Classification

PANTHER Family:	SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN (PTHR14166)
PANTHER Subfamily:	SLIT-ROBO RHO GTPASE-ACTIVATING PROTEIN 1 (PTHR14166:SF15)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	negative regulation of cell migration
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

Axon guidance mediated by Slit/Robo

Slit-Robo GTPase activating protein

PDGF signaling pathway

GTPase-activating protein Rho

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTPase activator activity, small GTPase binding
GO BP Complete:	Rho protein signal transduction, cell migration, negative regulation of cell migration
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RHO GTPase cycle, RHOA GTPase cycle, RAC1 GTPase cycle, Signaling by Rho GTPases, Signal Transduction, CDC42 GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17382\|UniProtKB=Q7Z6B7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005170.5\|UniProtKB=H2R1I1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000078.3\|UniProtKB=G3QCX6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001952.4\|UniProtKB=G7N7I9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2152936\|UniProtKB=Q91Z69	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000011892.6\|UniProtKB=F1MFS4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000029815.4\|UniProtKB=A0A287B9E3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011462.3\|UniProtKB=A0A3Q2HBR1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000019126.5\|UniProtKB=M3WPB8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010246.1\|UniProtKB=A0A8I3RVP5	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000047717.1\|UniProtKB=A0A6I8NV70	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012293.1\|UniProtKB=A0A8V0YF03	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003011.4\|UniProtKB=A0A803U1W2	Anolis carolinensis	LDO
XENLA\|Gene=LOC108713165\|UniProtKB=A0A8J0UXX7	Xenopus laevis	O
XENLA\|Gene=LOC108711074\|UniProtKB=A0A8J0UPN1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1013918\|UniProtKB=A0A6I8QYG9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017234.2\|UniProtKB=H2MS32	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016175.2\|UniProtKB=H2MND9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041210-103\|UniProtKB=B7ZVG9	Danio rerio	O
DANRE\|Gene=srgap1a\|UniProtKB=A0A8M6Z228	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016975.1\|UniProtKB=W5NK28	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004306.3\|UniProtKB=F6TSN4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118416686\|UniProtKB=A0A9J7L7Q4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594484\|UniProtKB=A0A7M7GG12	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00006406\|UniProtKB=Q19370	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00028452\|UniProtKB=A8X0U6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00103133\|UniProtKB=A0A2A6BE95	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP004772\|UniProtKB=A0A1S4GMU5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013589\|UniProtKB=A0A139WNS8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_49564\|UniProtKB=E9GER9	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022762\|UniProtKB=B7QC81	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG194472\|UniProtKB=T1FW34	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG191557\|UniProtKB=T1FT29	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG160724\|UniProtKB=T1EQN1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88221\|UniProtKB=A7RNI7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG55451\|UniProtKB=B3RUX8	Trichoplax adhaerens	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_90148\|UniProtKB=F4P7J0	Batrachochytrium dendrobatidis	LDO