PANTHER Gene Information   
Gene Symbol(s): Tp53bp1
Organism: Rattus norvegicus
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Gene Name: Tumor protein p53 binding protein 1
Gene ID: 1308039
Protein ID: F1M842
Persistent Id: PTN000393485
Alternate Ids:
1046882176(GI) 1308039(RGD)
F1M842(Synonym) ENSRNOG00000013837(Ensembl)
F1M842_RAT(UniProtKB-ID) 296099(GeneID)
ENSRNOP00000019025(Ensembl_PRO) ENSRNOT00000019025(Ensembl_TRS)
XM_017592215(refSeq)
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PANTHER Classification
PANTHER Family: TUMOR SUPPRESSOR P53-BINDING PROTEIN 1 (PTHR15321)
PANTHER Subfamily: TP53-BINDING PROTEIN 1 (PTHR15321:SF3)  
PANTHER GO-slim Molecular Function: histone binding
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
DNA damage checkpoint signaling
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: DNA metabolism protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: p53 binding, transcription coregulator activity, RNA polymerase II-specific DNA-binding transcription factor binding, telomeric DNA binding, histone binding, methylated histone binding, sequence-specific DNA binding, ubiquitin-modified histone reader activity, histone reader activity, damaged DNA binding
GO BP Complete: protein localization to site of double-strand break, DNA damage checkpoint signaling, DNA repair, cellular response to X-ray, negative regulation of double-strand break repair via homologous recombination, positive regulation of isotype switching, protein homooligomerization, double-strand break repair via nonhomologous end joining, chromatin organization, DNA damage response, positive regulation of transcription by RNA polymerase II, double-strand break repair via classical nonhomologous end joining
GO CC Complete: replication fork, chromosome, telomeric region, nucleus, nuclear body, site of double-strand break, cytoplasm, DNA repair complex, kinetochore, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G2/M DNA damage checkpoint, DNA Repair, Cell Cycle, Cell Cycle Checkpoints, Metabolism of proteins, Nonhomologous End-Joining (NHEJ), Post-translational protein modification, G2/M Checkpoints, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), DNA Double-Strand Break Repair, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, SUMO E3 ligases SUMOylate target proteins, SUMOylation of transcription factors, Homology Directed Repair, SUMOylation, DNA Double Strand Break Response, Processing of DNA double-strand break ends

Orthologs