PANTHER Gene Information   
Gene Symbol(s): SYK
Organism: Gallus gallus
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Gene Name: Tyrosine-protein kinase SYK
Gene ID: ENSGALG00010009340
Protein ID: F1N9Y5
Persistent Id: PTN000700494
Alternate Ids:
CAG32202(EMBL-CDS) AADN02069861(EMBL)
374110733(GI) ENSGALG00010009340(Ensembl)
KSYK(Synonym) 2.7.10.2(EC)
ENSGALP00010012784(Ensembl_PRO) NM_001031430(refSeq)
ENSGALT00015070158(Ensembl_TRS) 427272(GeneID)
KSYK_CHICK(UniProtKB-ID) Q5ZJ91(AltAccession)
SYK(Symbol)
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PANTHER Classification
PANTHER Family: TYROSINE-PROTEIN KINASE (PTHR24418)
PANTHER Subfamily: TYROSINE-PROTEIN KINASE SYK (PTHR24418:SF231)  
PANTHER GO-slim Molecular Function: protein tyrosine kinase activity
PANTHER GO-slim Biological Process: regulation of cell adhesion mediated by integrin
B cell receptor signaling pathway
macrophage activation involved in immune response
adaptive immune response
positive regulation of cell adhesion
neutrophil activation
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor tyrosine protein kinase
Pathway Categories: B cell activation
   Syk
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, protein tyrosine kinase activity, protein binding, non-membrane spanning protein tyrosine kinase activity, histone H2AXY142 kinase activity, histone H3Y41 kinase activity
GO BP Complete: peptidyl-tyrosine phosphorylation, regulation of arachidonate secretion, macrophage activation involved in immune response, neutrophil activation involved in immune response, blood vessel morphogenesis, regulation of platelet aggregation, leukocyte cell-cell adhesion, leukocyte activation involved in immune response, serotonin secretion by platelet, chromatin remodeling, integrin-mediated signaling pathway, regulation of superoxide anion generation, lymph vessel development, positive regulation of cell adhesion mediated by integrin, cellular response to hydrogen peroxide, intracellular signal transduction, B cell receptor signaling pathway, adaptive immune response, defense response to bacterium, regulation of neutrophil degranulation, regulation of ERK1 and ERK2 cascade, innate immune response, positive regulation of bone resorption, cellular response to molecule of fungal origin, neutrophil chemotaxis, regulation of platelet activation, regulation of phagocytosis
GO CC Complete: early phagosome, cytosol, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Innate Immune System, Platelet Aggregation (Plug Formation), Signaling by the B Cell Receptor (BCR), Regulation of signaling by CBL, Inactivation of CSF3 (G-CSF) signaling, Hemostasis, Signaling by Interleukins, Role of phospholipids in phagocytosis, Regulation of actin dynamics for phagocytic cup formation, Antigen activates B Cell Receptor (BCR) leading to generation of second messengers, GPVI-mediated activation cascade, Fcgamma receptor (FCGR) dependent phagocytosis, Signal Transduction, FCGR activation, Signaling by CSF3 (G-CSF), Immune System, DAP12 interactions, Cytokine Signaling in Immune system, Interleukin-3, Interleukin-5 and GM-CSF signaling, Adaptive Immune System, Platelet activation, signaling and aggregation, Integrin signaling, DAP12 signaling

Orthologs