PANTHER Gene Information

Gene Symbol(s):

wu:fb98d04

Organism:

Danio rerio

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Gene Name:

Huntingtin-interacting protein 1

Gene ID:

ZDB-GENE-010328-15

Protein ID:

F1R6L2

Persistent Id:

PTN000045194

Alternate Ids:

XP_005157489(refSeq)	CT027654(EMBL)
528501420(GI)	F1R6L2_DANRE(UniProtKB-ID)
F1R6L2(Synonym)	ENSDARG00000062972(Ensembl)
793823(GeneID)	ENSDART00000014465(Ensembl_TRS)
ENSDARP00000013812(Ensembl_PRO)	ZDB-GENE-010328-15(ZFIN)
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PANTHER Classification

PANTHER Family:	HUNTINGTIN INTERACTING PROTEIN 1 (PTHR10407)
PANTHER Subfamily:	HUNTINGTIN-INTERACTING PROTEIN 1 (PTHR10407:SF14)
PANTHER GO-slim Molecular Function:	anion binding protein-macromolecule adaptor activity actin filament binding clathrin binding phosphatidylinositol bisphosphate binding
PANTHER GO-slim Biological Process:	endocytosis actin filament organization protein-containing complex assembly activation of cysteine-type endopeptidase activity involved in apoptotic process
PANTHER GO-slim Cellular Component:	presynapse clathrin-coated vesicle cortical actin cytoskeleton
PANTHER protein class:	non-motor actin binding protein

Pathway Categories:

Huntington disease

Huntington interacting protein-1

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	actin filament binding, clathrin light chain binding, actin binding, phosphatidylinositol-3,5-bisphosphate binding, clathrin adaptor activity, clathrin binding, phospholipid binding, phosphatidylinositol-3,4-bisphosphate binding
GO BP Complete:	chordate embryonic development, clathrin coat assembly, response to yeast, positive regulation of epidermal growth factor receptor signaling pathway, actin filament organization, positive regulation of platelet-derived growth factor receptor-beta signaling pathway, regulation of apoptotic process, endocytosis
GO CC Complete:	presynapse, cytoplasm, clathrin-coated vesicle, cortical actin cytoskeleton

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4913\|UniProtKB=O00291	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000052483.1\|UniProtKB=A0A2I3SJJ6	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000051527.1\|UniProtKB=A0A2I3RBV2	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000048762.1\|UniProtKB=A0A2I3SYC1	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000019307.6\|UniProtKB=H2QUS3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016310.3\|UniProtKB=A0A2I2YCP9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005229.4\|UniProtKB=F7EPS9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1099804\|UniProtKB=Q8VD75	Mus musculus	LDO
RAT\|RGD=620305\|UniProtKB=G3V8Y8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000781.6\|UniProtKB=F1MWF0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007700.5\|UniProtKB=A0A8W4FBQ5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022880.4\|UniProtKB=A0A3Q2I4J6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004047.6\|UniProtKB=A0A337SSQ2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003838.1\|UniProtKB=A0A8I3MQX2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013732.4\|UniProtKB=A0A5F8H302	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003787.5\|UniProtKB=F6V0K8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029547.1\|UniProtKB=A0A8V1AKR3	Gallus gallus	LDO
XENLA\|Gene=hip1.L\|UniProtKB=A0A1L8HDW9	Xenopus laevis	O
XENLA\|Gene=hip1.S\|UniProtKB=A0A1L8H618	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-983522\|UniProtKB=F6Y171	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011517.2\|UniProtKB=A0A3B3I1A4	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000001155.1\|UniProtKB=W5LYY1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000001049.3\|UniProtKB=F6UP49	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425847\|UniProtKB=A0A9J7LXZ5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580390\|UniProtKB=A0A7M7RBH0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022717\|UniProtKB=Q02328	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG15345\|UniProtKB=A8XLZ9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00094897\|UniProtKB=A0A2A6CCY6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00283695\|UniProtKB=A0A8R1V0H5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036309\|UniProtKB=Q8MQJ8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004801\|UniProtKB=Q7PMU0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011686\|UniProtKB=D6X0H5	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW023307\|UniProtKB=B7QKD3	Ixodes scapularis	LDO
TRIAD\|EnsemblGenome=TriadG59009\|UniProtKB=B3S4A0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_6317\|UniProtKB=A9UTH2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_36287\|UniProtKB=A9UUA5	Monosiga brevicollis	LDO
YEAST\|SGD=S000005187\|UniProtKB=P33338	Saccharomyces cerevisiae	LDO
CANAL\|CGD=CAL0000178056\|UniProtKB=A0A1D8PRF5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C07502g\|UniProtKB=Q6CCQ4	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02756\|UniProtKB=Q5B9M4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G06140\|UniProtKB=Q4WWK0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01956\|UniProtKB=Q7SDY1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04007\|UniProtKB=A7EFB6	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00689\|UniProtKB=Q0V5M5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC688.11\|UniProtKB=Q9P6L5	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00152\|UniProtKB=B6JXL0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNE03040\|UniProtKB=Q5KGN0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00582\|UniProtKB=A0A0D1E8M4	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_20599\|UniProtKB=F4P9Y2	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_026370\|UniProtKB=C4M5V3	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_003930\|UniProtKB=C4M9B6	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0285703\|UniProtKB=Q1ZXE9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_48677\|UniProtKB=F0ZQ61	Dictyostelium purpureum	LDO