PANTHER Gene Information

Gene Symbol(s):

MSH4

Organism:

Arabidopsis thaliana

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Gene Name:

DNA mismatch repair protein MSH4

Gene ID:

2130913

Protein ID:

F4JP48

Persistent Id:

PTN000145758

Alternate Ids:

MSH4(Synonym)	AT4G17380(Ensembl_PRO)
MSH4(Symbol)	locus:2130913(TAIR)
AL161546(EMBL)	NP_193469(refSeq)
AT4G17380(Ensembl)	AAT70180(EMBL-CDS)
827450(GeneID)	7268490(GI)
Q6DTM5(AltAccession)	MSH4_ARATH(UniProtKB-ID)
AT4G17380(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER (PTHR11361)
PANTHER Subfamily:	MUTS PROTEIN HOMOLOG 4 (PTHR11361:SF21)
PANTHER GO-slim Molecular Function:	double-stranded DNA binding
PANTHER GO-slim Biological Process:	reciprocal meiotic recombination
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	double-stranded DNA binding, ATP-dependent DNA damage sensor activity, mismatched DNA binding
GO BP Complete:	reciprocal meiotic recombination, homologous chromosome segregation, mismatch repair, meiotic mismatch repair involved in reciprocal meiotic recombination, homologous chromosome pairing at meiosis
GO CC Complete:	nucleus, germ cell nucleus, plasmodesma, condensed nuclear chromosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7327\|UniProtKB=O15457	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000873.6\|UniProtKB=A0A2I3T501	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000044071.1\|UniProtKB=A0A2I2YCZ7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000875.4\|UniProtKB=F6TF84	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1860077\|UniProtKB=Q99MT2	Mus musculus	LDO
RAT\|RGD=1309190\|UniProtKB=F1M9U4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000018448.5\|UniProtKB=E1BK76	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003775.5\|UniProtKB=I3L5Z8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017096.4\|UniProtKB=A0A9L0SAU3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000039107.3\|UniProtKB=M3WNH7	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000019094.4\|UniProtKB=A0A5F8GRM5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014868.4\|UniProtKB=F6XXL7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024102.1\|UniProtKB=A0A8V0ZXY0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010892.4\|UniProtKB=A0A803TT17	Anolis carolinensis	LDO
XENLA\|Gene=msh4.L\|UniProtKB=A0A8J1MZ49	Xenopus laevis	LDO
XENTR\|Gene=msh4\|UniProtKB=A0A8J1JI83	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-953600\|UniProtKB=A0A6I8R2E8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016146.2\|UniProtKB=H2MNA6	Oryzias latipes	LDO
DANRE\|Gene=msh4\|UniProtKB=A0A8M3AK30	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011230.1\|UniProtKB=W5MZK1	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118413060\|UniProtKB=A0A9J7MM24	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC575381\|UniProtKB=A0A7M7ST06	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001872\|UniProtKB=Q23405	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG24743\|UniProtKB=A8WLD6	Caenorhabditis briggsae	LDO
ANOGA\|EnsemblGenome=AGAP012245\|UniProtKB=A0A1S4H8N7	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC006364\|UniProtKB=D6WWD2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303339\|UniProtKB=E9GFK0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022127\|UniProtKB=B7QDF1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG77646\|UniProtKB=T1G315	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214346\|UniProtKB=A7SM04	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51957\|UniProtKB=B3RLC4	Trichoplax adhaerens	LDO
YEAST\|SGD=S000001891\|UniProtKB=P40965	Saccharomyces cerevisiae	LDO
CANAL\|CGD=CAL0000197996\|UniProtKB=A0A1D8PS25	Candida albicans	LDO
ASPFU\|EnsemblGenome=AFUA_1G02000\|UniProtKB=Q4WKM0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU10895\|UniProtKB=A7UVX1	Neurospora crassa	LDO
PHANO\|EnsemblGenome=SNOG_03709\|UniProtKB=Q0UX05	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNL04240\|UniProtKB=Q5K8W7	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_12336\|UniProtKB=A0A0D1CF39	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_03119\|UniProtKB=E3JYN8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_25630\|UniProtKB=F4P553	Batrachochytrium dendrobatidis	LDO
TRIV3\|Gene_ORFName=TVAG_455180\|UniProtKB=A2FMY0	Trichomonas vaginalis	LDO
AMBTC\|EnsemblGenome=AMTR_s00111p00018680\|UniProtKB=W1NXS2	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_82G00120\|UniProtKB=A0A0K9NP06	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma08_g07850\|UniProtKB=A0A804K439	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_029133mg\|UniProtKB=K3ZRA3	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G304500\|UniProtKB=C5X8J8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb105070\|UniProtKB=A0A804MQY5	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_1g27377v3\|UniProtKB=I1GUD4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0126020\|UniProtKB=A0A8I6WQ37	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2A02G171900\|UniProtKB=A0A3B6ATZ7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G198300\|UniProtKB=A0A3B6C581	Triticum aestivum	LDO
NELNU\|Gene=LOC104598477\|UniProtKB=A0A1U8A269	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110794770\|UniProtKB=A0A9R0IUJ4	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0238701\|UniProtKB=A0A9K3IQD2	Helianthus annuus	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0238711\|UniProtKB=A0A251UEL6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300101440\|UniProtKB=A0A9R1W6J8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001574mg\|UniProtKB=A0A022PSG9	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc08g007330.3\|UniProtKB=A0A3Q7IEM5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107788296\|UniProtKB=A0A1S3ZLP2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107802422\|UniProtKB=A0A1S4AXM6	Nicotiana tabacum	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E00409\|UniProtKB=A0A059C171	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00026208001\|UniProtKB=A0A078J7U7	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra021052\|UniProtKB=M4DX06	Brassica campestris	LDO
GOSHI\|Gene=LOC107886066\|UniProtKB=A0A1U8HN04	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107944387\|UniProtKB=A0A1U8N3Y8	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_047017\|UniProtKB=A0A061G376	Theobroma cacao	LDO
POPTR\|Gene_ORFName=POPTR_001G156200\|UniProtKB=A0A3N7ECC0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G082400\|UniProtKB=A0A2C9WLG3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1389090\|UniProtKB=B9SXE1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G034600\|UniProtKB=K7LMU8	Glycine max	LDO
JUGRE\|EnsemblGenome=Jr02_10470\|UniProtKB=A0A2I4EIM9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G165160\|UniProtKB=A0A0A0KRC1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G066100\|UniProtKB=M5WFN5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_88599\|UniProtKB=D8R9L3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_115028\|UniProtKB=D8SEA9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c2_940\|UniProtKB=A9TGP2	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0001s0167\|UniProtKB=A0A2R6XVM1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002990050\|UniProtKB=A0A1Y1ICZ4	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_0080\|UniProtKB=Q8TUI7	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_2270G\|UniProtKB=Q9HN35	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0682\|UniProtKB=Q5JEZ3	Thermococcus kodakaraensis	O
METAC\|EnsemblGenome=MA_0523\|UniProtKB=Q8TTB4	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_0163G\|UniProtKB=Q9HSM2	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_0172G\|UniProtKB=Q9HSL6	Halobacterium salinarum	O
CLOBH\|Gene_OrderedLocusName=CBO1986\|UniProtKB=A5I3B1	Clostridium botulinum	O
STAA8\|EnsemblGenome=SAOUHSC_02276\|UniProtKB=Q2FWL3	Staphylococcus aureus	O
CLOBH\|Gene_OrderedLocusName=CBO1507\|UniProtKB=A5I1Y5	Clostridium botulinum	O
GLOVI\|Gene=Q7NE77_GLOVI\|UniProtKB=Q7NE77	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_4236\|UniProtKB=Q8EYH8	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_2697\|UniProtKB=Q8A4A6	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB9979\|UniProtKB=Q7UKS4	Rhodopirellula baltica	O
CHLAA\|EnsemblGenome=Caur_0339\|UniProtKB=A9WD21	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_0340\|UniProtKB=A9WD22	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2954\|UniProtKB=A9WFZ9	Chloroflexus aurantiacus	O
CLOBH\|Gene_OrderedLocusName=CBO1800\|UniProtKB=A5I2S2	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1888\|UniProtKB=P0A3R4	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01272\|UniProtKB=Q2FYZ9	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99481\|UniProtKB=Q8Y789	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_17040\|UniProtKB=P49849	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3769\|UniProtKB=Q81A25	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_1719\|UniProtKB=P74926	Thermotoga maritima	O
GLOVI\|EnsemblGenome=BAC88974\|UniProtKB=Q7NLT8	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA17821\|UniProtKB=P73769	Synechocystis	O
LEPIN\|EnsemblGenome=LA_2146\|UniProtKB=Q8F496	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_3121\|UniProtKB=Q8A334	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_792\|UniProtKB=O84797	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB7237\|UniProtKB=Q7UP05	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_308\|UniProtKB=O66652	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0706\|UniProtKB=B5YJY3	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1077\|UniProtKB=B8E279	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN0693\|UniProtKB=Q8RFK2	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB2160\|UniProtKB=Q9JX94	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU1822\|UniProtKB=P61667	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC46189\|UniProtKB=Q89VX1	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1056\|UniProtKB=Q83CQ2	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0707\|UniProtKB=P44834	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_3431\|UniProtKB=Q8EBR9	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0535\|UniProtKB=Q9KUI6	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC1207\|UniProtKB=Q8PBB5	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3620\|UniProtKB=Q9HY08	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2909\|UniProtKB=P0A1Y0	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0333\|UniProtKB=Q8ZBQ3	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76810\|UniProtKB=P23909	Escherichia coli	O