PANTHER Gene Information

Gene Symbol(s):

sprtn

Organism:

Xenopus tropicalis

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Gene Name:

DNA-dependent metalloprotease SPRTN

Gene ID:

XB-GENE-5845785

Protein ID:

F6UH96

Persistent Id:

PTN001845886

Alternate Ids:

sprtn{ECO:0000250\|UniProtKB:Q9H040}(Symbol)	163914881(GI)
SPRTN_XENTR(UniProtKB-ID)	NM_001113160(refSeq)
3.4.24.- {ECO:0000250\|UniProtKB:Q9H040}(EC)	AAMC01116774(EMBL)
A9JTW7(AltAccession)	AAI55518(EMBL-CDS)
Protein with SprT-like domain at the N terminus {ECO:0000250\|UniProtKB:Q9H040}(Synonym)	100127870(GeneID)
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PANTHER Classification

PANTHER Family:	DNA-DEPENDENT METALLOPROTEASE SPRTN (PTHR21220)
PANTHER Subfamily:	DNA-DEPENDENT METALLOPROTEASE SPRTN (PTHR21220:SF5)
PANTHER GO-slim Molecular Function:	polyubiquitin modification-dependent protein binding
PANTHER GO-slim Biological Process:	DNA damage response
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin binding, polyubiquitin modification-dependent protein binding, metal ion binding, K63-linked polyubiquitin modification-dependent protein binding, double-stranded DNA binding, metalloendopeptidase activity, single-stranded DNA binding, metallopeptidase activity
GO BP Complete:	DNA repair, proteolysis, positive regulation of protein ubiquitination, response to UV, protein autoprocessing, DNA damage response, translesion synthesis, protein-DNA covalent cross-linking repair
GO CC Complete:	nucleus, chromosome, chromatin

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template, DNA Repair, Translesion Synthesis by POLH, DNA Damage Bypass

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25356\|UniProtKB=Q9H040	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002109.7\|UniProtKB=H2Q1C7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003142.3\|UniProtKB=G3QKV4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005244.4\|UniProtKB=F7BW22	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2685351\|UniProtKB=G3X912	Mus musculus	LDO
RAT\|RGD=1559496\|UniProtKB=D3ZVU1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006112\|UniProtKB=A5D979	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000040087.3\|UniProtKB=A0A287ART8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023916.4\|UniProtKB=A0A9L0RUK0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000029939.4\|UniProtKB=A0A5F5XFZ4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000572.1\|UniProtKB=A0A8I3MAY5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000049042.1\|UniProtKB=A0A5F8GCW2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000048013.1\|UniProtKB=A0A6I8PQ39	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010007970.1\|UniProtKB=E1BQ54	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002853.4\|UniProtKB=G1KB79	Anolis carolinensis	LDO
XENLA\|Gene_ORFName=XELAEV_18029135mg\|UniProtKB=A0A1L8G2K9	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000017587.2\|UniProtKB=H2MTA5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-170317-1\|UniProtKB=A0A0G2L7I0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015764.1\|UniProtKB=W5NFJ7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023996.1\|UniProtKB=H2XPK8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118416103\|UniProtKB=A0A9J7L6W6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC762995\|UniProtKB=A0A7M7PW55	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00011834\|UniProtKB=Q22557	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00041551\|UniProtKB=E3CU94	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00272025\|UniProtKB=A0A2A6BLG0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092780\|UniProtKB=A0A2A6BKK4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00203500\|UniProtKB=A0A2A6C1J9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0267977\|UniProtKB=Q9VXU6	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001158\|UniProtKB=A0A1S4GB26	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004082\|UniProtKB=Q7QH54	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003998\|UniProtKB=D6WIH1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_49760\|UniProtKB=E9GFT6	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG73845\|UniProtKB=T1G1J2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g183924\|UniProtKB=A7RZX6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG30208\|UniProtKB=B3S6M2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_12453\|UniProtKB=A9VCB5	Monosiga brevicollis	LDO
PHANO\|EnsemblGenome=SNOG_10231\|UniProtKB=Q0UDD3	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_06861\|UniProtKB=Q0UN03	Phaeosphaeria nodorum	LDO
ENTH1\|EnsemblGenome=CL6EHI_104610\|UniProtKB=C4LZ70	Entamoeba histolytica	LDO
PLAF7\|EnsemblGenome=PF3D7_1338400\|UniProtKB=Q8IDU9	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00033419001\|UniProtKB=A0BYE9	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3G6P0_PHYRM\|UniProtKB=H3G6P0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g263100v5\|UniProtKB=A0A2K3DMV0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00156p00091480\|UniProtKB=W1PMD9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_137G00070\|UniProtKB=A0A0K9Q0G4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g17790\|UniProtKB=A0A804I3Y9	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3002G197200\|UniProtKB=A0A1B6QCE7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb312270\|UniProtKB=A0A1D6I433	Zea mays	O
ORYSJ\|EnsemblGenome=Os09g0407300\|UniProtKB=Q69MX9	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g29878v3\|UniProtKB=A0A2K2CR77	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0617630\|UniProtKB=A0A8I7BCG4	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G350700\|UniProtKB=A0A3B6PQZ0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G299400\|UniProtKB=A0A3B6QII8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G319900\|UniProtKB=A0A3B6NUZ1	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0479460\|UniProtKB=A0A8I6Y906	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5A02G204100\|UniProtKB=A0A3B6KGR0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G212000\|UniProtKB=A0A3B6MRM7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G204100\|UniProtKB=A0A3B6LMA4	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_035727mg\|UniProtKB=K4AA21	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G453500\|UniProtKB=C5WSQ1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb008890\|UniProtKB=A0A804LG86	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_1g69655v3\|UniProtKB=A0A0Q3KEH2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0395990\|UniProtKB=A0A8I6XJL9	Hordeum vulgare subsp. vulgare	LDO
SELML\|EnsemblGenome=SELMODRAFT_447527\|UniProtKB=D8T076	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_415131\|UniProtKB=D8RV46	Selaginella moellendorffii	O
KLENI\|Gene_ORFName=KFL_000010430\|UniProtKB=A0A0U9HIH2	Klebsormidium nitens	LDO