PANTHER Gene Information

Gene Symbol(s):

PNPLA4

Organism:

Macaca mulatta

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Gene Name:

Patatin like phospholipase domain containing 4

Gene ID:

ENSMMUG00000018194.4

Protein ID:

F7E9K3

Persistent Id:

PTN008995280

Alternate Ids:

F7E9K3(Synonym)	ENSMMUP00000023933(Ensembl_PRO)
F7E9K3_MACMU(UniProtKB-ID)	ENSMMUT00000025579(Ensembl_TRS)
708139(GeneID)	NP_001180773(refSeq)
ENSMMUG00000018194(Ensembl)	302564249(GI)
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PANTHER Classification

PANTHER Family:	CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED (PTHR12406)
PANTHER Subfamily:	PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4 (PTHR12406:SF7)
PANTHER GO-slim Molecular Function:	triglyceride lipase activity
PANTHER GO-slim Biological Process:	lipid homeostasis triglyceride catabolic process
PANTHER GO-slim Cellular Component:	membrane cytoplasm lipid droplet
PANTHER protein class:	phospholipase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	phospholipase A2 activity, mono-olein transacylation activity, catalytic activity, diolein transacylation activity, retinyl-palmitate esterase activity, triacylglycerol lipase activity, acylglycerol O-acyltransferase activity, hydrolase activity
GO BP Complete:	lipid homeostasis, lipid catabolic process, retinol metabolic process, triglyceride catabolic process
GO CC Complete:	lipid droplet, cytoplasm, mitochondrion, membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24887\|UniProtKB=P41247	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021641.5\|UniProtKB=H2QY97	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005430.3\|UniProtKB=G3QRQ4	Gorilla gorilla gorilla	LDO
RAT\|RGD=1562200\|UniProtKB=A0A8I6ABA3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015849.5\|UniProtKB=G3X777	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000038027.3\|UniProtKB=F1SG26	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013103.4\|UniProtKB=F6R9V1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004082.6\|UniProtKB=M3W1J2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845024459.1\|UniProtKB=A0A8I3Q2G7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017500.3\|UniProtKB=F7F1B0	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010001713.1\|UniProtKB=A0A1D6UPU4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000415.4\|UniProtKB=G1K8H3	Anolis carolinensis	LDO
XENLA\|Gene=pnpla4.L\|UniProtKB=Q5M9B2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-968680\|UniProtKB=F6SLH7	Xenopus tropicalis	LDO
LEPOC\|Ensembl=ENSLOCG00000010156.1\|UniProtKB=W5MVM7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118428314\|UniProtKB=A0A9J7M432	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115925515\|UniProtKB=A0A7M7P8F2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115925507\|UniProtKB=A0A7M7P8C0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763231\|UniProtKB=A0A7M7P3G7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763218\|UniProtKB=A0A7M7P2Y9	Strongylocentrotus purpuratus	LDO
HELRO\|EnsemblGenome=HelroG75153\|UniProtKB=T1G215	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g192317\|UniProtKB=A7SQ61	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_23560\|UniProtKB=A9UTT0	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_22555\|UniProtKB=F4NV55	Batrachochytrium dendrobatidis	LDO
LEIMA\|EnsemblGenome=LMJF_34_2910\|UniProtKB=Q4Q2Q3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.4.1780\|UniProtKB=Q581Q3	Trypanosoma brucei	O
PHYRM\|Gene=H3GIV2_PHYRM\|UniProtKB=H3GIV2	Phytophthora ramorum	O
PHYRM\|Gene=H3H3W6_PHYRM\|UniProtKB=H3H3W6	Phytophthora ramorum	O
PHYRM\|Gene=H3H459_PHYRM\|UniProtKB=H3H459	Phytophthora ramorum	O
PHYRM\|Gene=H3H460_PHYRM\|UniProtKB=H3H460	Phytophthora ramorum	O
LEIMA\|EnsemblGenome=LMJF_13_1150\|UniProtKB=Q4QG39	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.1440\|UniProtKB=Q386C0	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_0218600\|UniProtKB=O96266	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_9458\|UniProtKB=B8CBD8	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_2521\|UniProtKB=B8BUL3	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3H4J5_PHYRM\|UniProtKB=H3H4J5	Phytophthora ramorum	O
PHYRM\|Gene=H3H3B2_PHYRM\|UniProtKB=H3H3B2	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_04g214700v5\|UniProtKB=A0A2K3DTR7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g462000v5\|UniProtKB=A0A2K3DBZ3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_26g756847v5\|UniProtKB=A0A2K3CN09	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g431350v5\|UniProtKB=A8IBA6	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_003100140\|UniProtKB=A0A1Y1IDI1	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_03g195500v5\|UniProtKB=A0A2K3DYL8	Chlamydomonas reinhardtii	LDO
CHLRE\|EnsemblGenome=CHLRE_03g175100v5\|UniProtKB=A0A2K3DXB5	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g400219v5\|UniProtKB=A0A2K3DEX6	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g530950v5\|UniProtKB=A0A2K3D4U4	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00008p00125700\|UniProtKB=W1NHN9	Amborella trichopoda	LDO
MUSAM\|EnsemblGenome=Ma03_g01710\|UniProtKB=A0A804I7D4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_026450mg\|UniProtKB=K3ZIP8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3005G144300\|UniProtKB=C5Y3W6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb113740\|UniProtKB=B4F8G3	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os11g0546300\|UniProtKB=Q0IS87	Oryza sativa	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0182880\|UniProtKB=A0A8I6WG23	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2A02G377000\|UniProtKB=A0A3B6B1H0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G373600\|UniProtKB=A0A1D5UIX7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G394200\|UniProtKB=A0A3B6C9U7	Triticum aestivum	LDO
SPIOL\|Gene=LOC110783510\|UniProtKB=A0A9R0JR43	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr02g0058791\|UniProtKB=A0A251VIZ4	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0270561\|UniProtKB=A0A9K3IUU6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0486811\|UniProtKB=A0A251TCP3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700372630\|UniProtKB=A0A9R1V3R5	Lactuca sativa	LDO
CAPAN\|EnsemblGenome=T459_34251\|UniProtKB=A0A2G2XWI8	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400023754\|UniProtKB=M1C6Z3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g104310.3\|UniProtKB=A0A3Q7ERW0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107829125\|UniProtKB=A0A1S4DFD8	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107780405\|UniProtKB=A0A1S3YX46	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi12g01816\|UniProtKB=D7T034	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G00613\|UniProtKB=A0A059BAH5	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C06P12670.1\|UniProtKB=A0A078J0B5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra041092\|UniProtKB=A0A397XX23	Brassica campestris	LDO
BRANA\|Gene_ORFName=GSBRNA2T00021574001\|UniProtKB=A0A078G9J4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00081127001\|UniProtKB=A0A078I505	Brassica napus	O
BRACM\|EnsemblGenome=Bra036734\|UniProtKB=M4F6M4	Brassica campestris	O
ARATH\|TAIR=locus=2196685\|UniProtKB=Q6NPP7	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107938399\|UniProtKB=A0A1U8MJR7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107936982\|UniProtKB=A0A1U8MEJ5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107932420\|UniProtKB=A0A1U8M2X1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928966\|UniProtKB=A0A1U8LRD8	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107939224\|UniProtKB=A0A1U8MR58	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_006407\|UniProtKB=A0A061DZ51	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g015942mg\|UniProtKB=A0A067EJ17	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_003G020800v3\|UniProtKB=A0A2K2B094	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G209500v3\|UniProtKB=A9PFI5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_07G014400\|UniProtKB=A0A2C9VJ48	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1411270\|UniProtKB=B9SRI9	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G184900\|UniProtKB=K7L7H6	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_15G047800\|UniProtKB=I1MDQ4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g007650\|UniProtKB=A2Q497	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_19530\|UniProtKB=A0A2I4FV16	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G214570\|UniProtKB=A0A0A0L746	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G566300\|UniProtKB=A0A251RJ53	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_103868\|UniProtKB=D8RXH3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_99699\|UniProtKB=D8RRL1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_103449\|UniProtKB=D8RXG7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c11_20720\|UniProtKB=A0A2K1JVH4	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0101s0012\|UniProtKB=A0A2R6WEC8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000290010\|UniProtKB=A0A1Y1HNP0	Klebsormidium nitens	LDO