PANTHER Gene Information   
Gene Symbol(s): Prpf8
Organism: Rattus norvegicus
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Gene Name: Pre-mRNA processing factor 8
Gene ID: 1305467
Protein ID: G3V6H2
Persistent Id: PTN000124574
Alternate Ids:
G3V6H2_RAT(UniProtKB-ID) NP_001178519(refSeq)
G3V6H2(Synonym) ENSRNOG00000003495(Ensembl)
ENSRNOT00000005016(Ensembl_TRS) 287530(GeneID)
1305467(RGD) ENSRNOP00000005016(Ensembl_PRO)
300797649(GI)
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PANTHER Classification
PANTHER Family: PRE-MRNA SPLICING FACTOR PRP8 (PTHR11140)
PANTHER Subfamily: PRE-MRNA-PROCESSING-SPLICING FACTOR 8 (PTHR11140:SF0)  
PANTHER GO-slim Molecular Function: pre-mRNA binding
snRNA binding
PANTHER GO-slim Biological Process: spliceosomal snRNP assembly
PANTHER GO-slim Cellular Component: U5 snRNP
catalytic step 2 spliceosome
PANTHER protein class: RNA splicing factor
Pathway Categories: No pathway information available
GO MF Complete: U6 snRNA binding, U5 snRNA binding, pre-mRNA intronic binding, protein binding, K63-linked polyubiquitin modification-dependent protein binding, U1 snRNA binding, U2 snRNA binding, metallopeptidase activity
GO BP Complete: cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, spliceosomal tri-snRNP complex assembly, mRNA splicing, via spliceosome
GO CC Complete: nucleus, catalytic step 2 spliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, U2-type catalytic step 1 spliceosome, U2-type catalytic step 2 spliceosome, U2-type precatalytic spliceosome, small nuclear ribonucleoprotein complex
Reactome Pathways: Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing - Minor Pathway, mRNA Splicing - Major Pathway, Metabolism of RNA, mRNA Splicing