PANTHER Gene Information

Gene Symbol(s):

hcf-1

Organism:

Caenorhabditis elegans

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Gene Name:

Host cell factor homolog hcf-1

Gene ID:

WBGene00001827

Protein ID:

G5EC23

Persistent Id:

PTN000582406

Alternate Ids:

NM_068878(refSeq)	3851534(GI)
CCD66593(EMBL-CDS)	HCF1_CAEEL(UniProtKB-ID)
C46A5.9(Ensembl_TRS)	AF072907(EMBL)
HCF homolog {ECO:0000303\|PubMed:9858614}(Synonym)	hcf-1{ECO:0000312\|WormBase:C46A5.9}(Symbol)
WBGene00001827(Ensembl)	C46A5.9(Ensembl_PRO)
CE26914(WormBase_PRO)	C46A5(WormBase_TRS)
177560(GeneID)	WBGene00001827(WormBase)
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PANTHER Classification

PANTHER Family:	HOST CELL FACTOR (PTHR46003)
PANTHER Subfamily:	HOST CELL FACTOR (PTHR46003:SF1)
PANTHER GO-slim Molecular Function:	transcription coactivator activity
PANTHER GO-slim Biological Process:	chromatin remodeling regulation of DNA-templated transcription
PANTHER GO-slim Cellular Component:	histone methyltransferase complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	transcription coregulator binding, protein binding, transcription coactivator activity, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity, DNA-binding transcription factor binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, response to oxidative stress, negative regulation of protein localization to nucleus, chromatin remodeling, determination of adult lifespan, dauer exit, regulation of DNA-templated transcription, negative regulation of transcription by transcription factor localization, response to cadmium ion, positive regulation of transcription by RNA polymerase II, response to endoplasmic reticulum stress
GO CC Complete:	nucleus, transcription regulator complex, histone methyltransferase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Gene expression (Transcription), Epigenetic regulation of gene expression, Formation of WDR5-containing histone-modifying complexes

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24972\|UniProtKB=Q9Y5Z7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005375.5\|UniProtKB=H2Q6R5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000026557.2\|UniProtKB=A0A2I2YK61	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000057796.1\|UniProtKB=F6ZF51	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915183\|UniProtKB=Q9D968	Mus musculus	LDO
RAT\|RGD=1307385\|UniProtKB=Q5RKG2	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020933.6\|UniProtKB=E1BEJ7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000846.5\|UniProtKB=F1SRK9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023836.4\|UniProtKB=F6Y1K7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014081.6\|UniProtKB=A0A337SKD6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010878.1\|UniProtKB=A0A8I3RYC6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000002178.4\|UniProtKB=F7GEG5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005549.4\|UniProtKB=A0A6I8PNB1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011883.1\|UniProtKB=A0A8V0YF01	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016051.4\|UniProtKB=G1KS35	Anolis carolinensis	LDO
XENLA\|Gene=LOC121402040\|UniProtKB=A0A8J1MPN1	Xenopus laevis	O
XENLA\|Gene=LOC108711028\|UniProtKB=A0A8J0UTV9	Xenopus laevis	LDO
XENTR\|Gene=hcfc2\|UniProtKB=A0A8J0R2R1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009281.2\|UniProtKB=H2LZR7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050417-203\|UniProtKB=X1WCP5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015033.1\|UniProtKB=W5NCZ6	lepisosteus oculatus	LDO
RAT\|RGD=621114\|UniProtKB=A0A8I5ZUN3	Rattus norvegicus	O
XENLA\|Gene=LOC108702272\|UniProtKB=A0A8J1LXG7	Xenopus laevis	O
DANRE\|Gene=ttn.1\|UniProtKB=A0A8M9QGA6	Danio rerio	O
DANRE\|Gene=ttn.2\|UniProtKB=A0A8M9QKG2	Danio rerio	O
HUMAN\|HGNC=4839\|UniProtKB=P51610	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043866.1\|UniProtKB=A0A2I3SK58	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009800.3\|UniProtKB=G3R2W8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000319.4\|UniProtKB=A0A1D5QJR4	Macaca mulatta	O
MOUSE\|MGI=MGI=105942\|UniProtKB=Q61191	Mus musculus	O
RAT\|RGD=1563804\|UniProtKB=D3ZN95	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011904.6\|UniProtKB=E1BGF3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000012793.6\|UniProtKB=A0A8W4F7H9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000022440.3\|UniProtKB=F6TVL2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011387.6\|UniProtKB=A0A2I2U583	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026790.1\|UniProtKB=A0A8I3Q080	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011597.5\|UniProtKB=F6UZE6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005871.4\|UniProtKB=F6W3P2	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000012364.4\|UniProtKB=G1KMB6	Anolis carolinensis	O
XENLA\|Gene=LOC108704501\|UniProtKB=A0A8J1LHP1	Xenopus laevis	O
XENLA\|Gene=hcfc1.S\|UniProtKB=Q640G9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6076923\|UniProtKB=A0A8J0SLM0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000014012.2\|UniProtKB=H2MG37	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030912-10\|UniProtKB=A0A8M3AXL2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-2411\|UniProtKB=A0A8M9PQY4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014733.1\|UniProtKB=W5NBZ7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000007967.3\|UniProtKB=F6Z7N3	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC586153\|UniProtKB=A0A7M7T5X4	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG17668\|UniProtKB=A8XRK3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00277131\|UniProtKB=A0A2A6CBR0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0039904\|UniProtKB=Q9V4C8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004774\|UniProtKB=A0A1S4GM46	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC034515\|UniProtKB=A0A139WNU8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_306973\|UniProtKB=E9H072	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG53229\|UniProtKB=B3RNN4	Trichoplax adhaerens	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34223\|UniProtKB=F4NT19	Batrachochytrium dendrobatidis	LDO