PANTHER Gene Information

Gene Symbol(s):

mrp-5

Organism:

Caenorhabditis elegans

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Multidrug resistance-associated protein 5

Gene ID:

WBGene00003411

Protein ID:

G5EE72

Persistent Id:

PTN000658123

Alternate Ids:

181587(GeneID)	1835921943(GI)
CE23650(WormBase_PRO)	WBGene00003411(WormBase)
F14F4.3(Ensembl_PRO)	F14F4(WormBase_TRS)
mrp-5{ECO:0000312\|WormBase:F14F4.3}(Symbol)	MRP5(Synonym)
BX284606(EMBL)	F14F4.3(Ensembl_TRS)
WBGene00003411(Ensembl)	CAB54225(EMBL-CDS)
MRP5_CAEEL(UniProtKB-ID)	NP_510479(refSeq)
Show All

PANTHER Classification

PANTHER Family:	ATP-BINDING CASSETTE SUB-FAMILY C (PTHR24223)
PANTHER Subfamily:	MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 (PTHR24223:SF447)
PANTHER GO-slim Molecular Function:	ATPase-coupled transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport
PANTHER GO-slim Cellular Component:	membrane
PANTHER protein class:	ATP-binding cassette (ABC) transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, ATPase-coupled transmembrane transporter activity, ABC-type vitamin B12 transporter activity, ABC-type transporter activity
GO BP Complete:	transmembrane transport, cobalamin transport
GO CC Complete:	membrane, basolateral plasma membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Drug ADME, Glycosaminoglycan metabolism, Azathioprine ADME, Transport of small molecules, Hyaluronan metabolism, Metabolism of carbohydrates, ABC-family proteins mediated transport, Metabolism, Paracetamol ADME, Hyaluronan biosynthesis and export

Orthologs

ID	Organism	Type
HUMAN\|HGNC=14639\|UniProtKB=Q96J66	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000008092.6\|UniProtKB=A0A2I3SB69	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005674.3\|UniProtKB=A0A2I2YZL2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008290.4\|UniProtKB=F7H940	Macaca mulatta	O
BOVIN\|Ensembl=ENSBTAG00000010858.6\|UniProtKB=F1N4I6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000032298.3\|UniProtKB=A0A286ZK20	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021168.4\|UniProtKB=F6UID9	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005280.6\|UniProtKB=A0A2I2UPC7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845004630.1\|UniProtKB=A0A8I3N9B0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000029131.2\|UniProtKB=K7E6A1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014849.4\|UniProtKB=F7BXT9	Ornithorhynchus anatinus	O
HUMAN\|HGNC=14640\|UniProtKB=Q96J65	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008091.6\|UniProtKB=H2QB21	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004009.3\|UniProtKB=G3QN33	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002201.4\|UniProtKB=F6WF81	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2441679\|UniProtKB=Q80WJ6	Mus musculus	LDO
RAT\|RGD=735100\|UniProtKB=Q6Y306	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000044191.3\|UniProtKB=E1BM99	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000022813.4\|UniProtKB=I3LQK0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019541.4\|UniProtKB=A0A3Q2GYE9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005279.6\|UniProtKB=M3W3S9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004726.1\|UniProtKB=A0A8I3MYB2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000012914.4\|UniProtKB=F7GCF3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014850.3\|UniProtKB=F7BXS7	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000014129.4\|UniProtKB=H9GKW3	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000014988.2\|UniProtKB=H2MJE2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050517-25\|UniProtKB=F8W557	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005287.1\|UniProtKB=W5MDB7	lepisosteus oculatus	LDO
HUMAN\|HGNC=56\|UniProtKB=O15440	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000050934.1\|UniProtKB=K7AN90	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000418.3\|UniProtKB=A0A2I2ZTH7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000005515.4\|UniProtKB=H9FND4	Macaca mulatta	O
MOUSE\|MGI=MGI=1351644\|UniProtKB=Q9R1X5	Mus musculus	O
RAT\|RGD=70913\|UniProtKB=Q9QYM0	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000017666.6\|UniProtKB=F1MZD4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000011782.5\|UniProtKB=A0A287AY60	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007961.4\|UniProtKB=F6WGY5	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000007784.6\|UniProtKB=A0A337S593	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024339.1\|UniProtKB=A0A8I3PVZ3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003135.6\|UniProtKB=F6WVF1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008866.3\|UniProtKB=A0A6I8MZ00	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010017985.1\|UniProtKB=A0A8V0Z5L8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000010771.4\|UniProtKB=A0A803T9L3	Anolis carolinensis	O
XENLA\|Gene=LOC108708425\|UniProtKB=A0A1L8HGV6	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000034322\|UniProtKB=A0A6I8SLZ6	Xenopus tropicalis	O
XENLA\|Gene=abcc5.L\|UniProtKB=A0A1L8GA45	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-979047\|UniProtKB=F6R6C7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000000781.2\|UniProtKB=H2L592	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-140106-124\|UniProtKB=A0A0R4IV86	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015366.1\|UniProtKB=W5NE66	lepisosteus oculatus	O
DANRE\|ZFIN=ZDB-GENE-050517-17\|UniProtKB=E1B2R7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000008431.1\|UniProtKB=W5MPG4	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008955.3\|UniProtKB=F6Q5Y8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118403441\|UniProtKB=A0A9J7HGZ8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426875\|UniProtKB=A0A9J7M1M9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403624\|UniProtKB=A0A9J7HJC0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427078\|UniProtKB=A0A9J7M1A6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426887\|UniProtKB=A0A9J7M0V7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403448\|UniProtKB=A0A9J7HGP7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411115\|UniProtKB=A0A9J7KSL4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426876\|UniProtKB=A0A9J7M1C3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105447431\|UniProtKB=A0A7M7NK53	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_582885\|UniProtKB=H9CNL1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918584\|UniProtKB=A0A7M7NQX2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC582918\|UniProtKB=A0A7M7NKS0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590330\|UniProtKB=A0A7M7NKP0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594398\|UniProtKB=A0A7M7NKG5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590270\|UniProtKB=A0A7M7RE92	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC582468\|UniProtKB=A0A7M7NJA8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590074\|UniProtKB=A0A7M7PMA9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584425\|UniProtKB=A0A7M7NLH3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591705\|UniProtKB=A0A7M7NLI1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC593868\|UniProtKB=A0A7M7NJQ7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578391\|UniProtKB=A0A7M7NJL1	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC594581\|UniProtKB=A0A7M7SX21	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG07659\|UniProtKB=A8X4C6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00115900\|UniProtKB=A0A8R1YJA7	Pristionchus pacificus	LDO
DAPPU\|Gene_ORFName=DAPPUDRAFT_347548\|UniProtKB=E9HWN6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347292\|UniProtKB=E9H6H0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347295\|UniProtKB=E9H6H1	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG110482\|UniProtKB=T1EF27	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136552\|UniProtKB=A7SXB5	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG57243\|UniProtKB=B3RYW9	Trichoplax adhaerens	LDO
TRIAD\|EnsemblGenome=TriadG19489\|UniProtKB=B3RLX4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26283\|UniProtKB=B3RYW8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG19283\|UniProtKB=B3RLZ7	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25070\|UniProtKB=A9UYB9	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_82\|UniProtKB=A9UWP0	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_8420\|UniProtKB=F4NUF5	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_21115\|UniProtKB=F4PER9	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_124840\|UniProtKB=C4M978	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0284867\|UniProtKB=Q54P13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_47315\|UniProtKB=F0ZIX3	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00001809001\|UniProtKB=A0D6V1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028165001\|UniProtKB=A0BF13	Paramecium tetraurelia	O
PHYRM\|Gene=H3HEF0_PHYRM\|UniProtKB=H3HEF0	Phytophthora ramorum	O
PHYRM\|Gene=H3HCF6_PHYRM\|UniProtKB=H3HCF6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD40_PHYRM\|UniProtKB=H3HD40	Phytophthora ramorum	O
PHYRM\|Gene=H3HE07_PHYRM\|UniProtKB=H3HE07	Phytophthora ramorum	O
PHYRM\|Gene=H3GAE6_PHYRM\|UniProtKB=H3GAE6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD38_PHYRM\|UniProtKB=H3HD38	Phytophthora ramorum	O
PHYRM\|Gene=H3H408_PHYRM\|UniProtKB=H3H408	Phytophthora ramorum	O
PHYRM\|Gene=H3GKM1_PHYRM\|UniProtKB=H3GKM1	Phytophthora ramorum	O
PHYRM\|Gene=H3GJD8_PHYRM\|UniProtKB=H3GJD8	Phytophthora ramorum	O
PHYRM\|Gene=H3H2W5_PHYRM\|UniProtKB=H3H2W5	Phytophthora ramorum	O
PHYRM\|Gene=H3H5U8_PHYRM\|UniProtKB=H3H5U8	Phytophthora ramorum	O
PHYRM\|Gene=H3HE89_PHYRM\|UniProtKB=H3HE89	Phytophthora ramorum	O
PHYRM\|Gene=H3GAR7_PHYRM\|UniProtKB=H3GAR7	Phytophthora ramorum	O
PHYRM\|Gene=H3G9K9_PHYRM\|UniProtKB=H3G9K9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_08g369720v5\|UniProtKB=A0A2K3DH39	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g325761v5\|UniProtKB=A0A2K3DJI3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_08g369850v5\|UniProtKB=A0A2K3DH80	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g174050v5\|UniProtKB=A0A2K3DX98	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_003420130\|UniProtKB=A0A1Y1I8H3	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_02g097800v5\|UniProtKB=A0A2K3E226	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g734612v5\|UniProtKB=Q50JT7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g564900v5\|UniProtKB=A0A2K3CZ64	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g103250v5\|UniProtKB=A0A2K3E2F8	Chlamydomonas reinhardtii	O
MARPO\|EnsemblGenome=MARPO_0133s0051\|UniProtKB=A0A2R6W7S7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_004930030\|UniProtKB=A0A1Y1IDX7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000850340\|UniProtKB=A0A1Y1I0J0	Klebsormidium nitens	O