PANTHER Gene Information

Gene Symbol(s):

lin-22

Organism:

Caenorhabditis elegans

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Gene Name:

Helix-loop-helix protein lin-22

Gene ID:

WBGene00003008

Protein ID:

G5EF76

Persistent Id:

PTN000105687

Alternate Ids:

WBGene00003008(Ensembl)	LIN22_CAEEL(UniProtKB-ID)
351051318(GI)	NM_067880(refSeq)
CE26703(WormBase_PRO)	177082(GeneID)
Y54G2A(WormBase_TRS)	LIN22(Synonym)
CCD83486(EMBL-CDS)	Y54G2A.1(Ensembl_PRO)
Y54G2A.1(Ensembl_TRS)	AF020555(EMBL)
WBGene00003008(WormBase)	lin-22{ECO:0000312\|WormBase:Y54G2A.1}(Symbol)
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PANTHER Classification

PANTHER Family:	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED (PTHR10985)
PANTHER Subfamily:	HELIX-LOOP-HELIX PROTEIN LIN-22 (PTHR10985:SF152)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	anterior/posterior pattern specification regulation of transcription by RNA polymerase II regulation of neurogenesis
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of gene expression, epidermal cell fate specification, anterior/posterior pattern specification, nematode male tail tip morphogenesis, regulation of neurogenesis, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19764\|UniProtKB=Q5TA89	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000024233.5\|UniProtKB=H2R0I1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010276.3\|UniProtKB=G3R439	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000063558.1\|UniProtKB=A0A5F7Z9I3	Macaca mulatta	O
MOUSE\|MGI=MGI=104876\|UniProtKB=P70120	Mus musculus	O
RAT\|RGD=621340\|UniProtKB=Q03062	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002483.6\|UniProtKB=A0A3S5ZPR6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037304.3\|UniProtKB=A0A287BCL3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000036474.2\|UniProtKB=A0A3Q2GXV6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000040380.2\|UniProtKB=A0A337RWC8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018404.1\|UniProtKB=A0A8I3P2K3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008212.3\|UniProtKB=F6ZYK3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000008220.4\|UniProtKB=F6ZYD3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000038720.1\|UniProtKB=A0A6I8P3L1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010019724.1\|UniProtKB=A0A8V0ZAH0	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010019700.1\|UniProtKB=A0A8V0Z4K0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003188.3\|UniProtKB=H9G753	Anolis carolinensis	O
XENLA\|Gene=hes5.10.L\|UniProtKB=Q9PTN9	Xenopus laevis	O
XENLA\|Gene=hes5.10.S\|UniProtKB=A0A1L8FGJ5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-876529\|UniProtKB=Q28F58	Xenopus tropicalis	O
XENLA\|Gene=hes5.4.L\|UniProtKB=A0A0U2KF03	Xenopus laevis	O
XENLA\|Gene=hes5.4.S\|UniProtKB=A0A1L8FGF9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5952810\|UniProtKB=A0A6I8PZ59	Xenopus tropicalis	O
XENLA\|Gene=hes5.1.S\|UniProtKB=Q53U31	Xenopus laevis	O
XENLA\|Gene=hes5.1.L\|UniProtKB=Q7ZYL8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-481135\|UniProtKB=Q28J62	Xenopus tropicalis	O
XENLA\|Gene=hes5.5.S\|UniProtKB=B7ZQH5	Xenopus laevis	O
XENLA\|Gene=hes5.5.L\|UniProtKB=A0A1L8FMI1	Xenopus laevis	O
XENLA\|Gene=hes5.8.S\|UniProtKB=A0A1L8FGI2	Xenopus laevis	O
XENLA\|Gene=hes5.8.L\|UniProtKB=A0A1L8FMJ3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-22064040\|UniProtKB=A0A8J0QKK9	Xenopus tropicalis	O
XENLA\|Gene=hes5.3.S\|UniProtKB=A0A1L8FGI3	Xenopus laevis	O
XENLA\|Gene=hes5.2.S\|UniProtKB=Q53U32	Xenopus laevis	O
XENLA\|Gene=hes5.3.L\|UniProtKB=Q90Z13	Xenopus laevis	O
XENLA\|Gene=hes5.2.L\|UniProtKB=Q9PTN8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-876635\|UniProtKB=Q28FS4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000003974.2\|UniProtKB=Q1L7T5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-521\|UniProtKB=Q90466	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-081030-7\|UniProtKB=B0V3D2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-081031-104\|UniProtKB=B0V3D3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-060815-1\|UniProtKB=B0V3D1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030707-2\|UniProtKB=Q7T3J0	Danio rerio	O
DANRE\|Gene=her2\|UniProtKB=A0A8M2B2B4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004724.1\|UniProtKB=W5MBA4	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000004707.1\|UniProtKB=W5MB84	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000003967.2\|UniProtKB=Q1L7T9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040824-5\|UniProtKB=Q6TA36	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004739.1\|UniProtKB=W5MBG7	lepisosteus oculatus	O
HUMAN\|HGNC=16617\|UniProtKB=Q9C0J9	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004779.5\|UniProtKB=H2Q5M4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015498.3\|UniProtKB=G3RHJ7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000039562.2\|UniProtKB=A0A1D5QXB6	Macaca mulatta	O
MOUSE\|MGI=MGI=1930704\|UniProtKB=Q99PV5	Mus musculus	O
RAT\|RGD=70900\|UniProtKB=O35779	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000030575.4\|UniProtKB=Q0VCT6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000028552.4\|UniProtKB=A0A287AYR6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000034955.3\|UniProtKB=A0A3Q2LSV6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000042690.2\|UniProtKB=A0A5F5Y044	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026188.1\|UniProtKB=A0A8I3PND5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016551.4\|UniProtKB=F7DNT3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000040055.1\|UniProtKB=A0A6I8P109	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010014338.1\|UniProtKB=A0A3Q2UG86	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000036732.1\|UniProtKB=A0A803TLL4	Anolis carolinensis	O
XENLA\|Gene=LOC108712523\|UniProtKB=A0A1L8GQD9	Xenopus laevis	O
XENLA\|Gene=LOC108710706\|UniProtKB=A0A1L8GVX4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-994875\|UniProtKB=Q4V788	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000011401.2\|UniProtKB=Q2L4U3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050419-146\|UniProtKB=Q2PGD2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015327.1\|UniProtKB=W5NE00	lepisosteus oculatus	O
HUMAN\|HGNC=16005\|UniProtKB=Q9Y543	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000000085.7\|UniProtKB=H2PXW9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001846.3\|UniProtKB=G3SAB1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022882.4\|UniProtKB=A0A1D5R8B9	Macaca mulatta	O
MOUSE\|MGI=MGI=1098624\|UniProtKB=O54792	Mus musculus	O
RAT\|RGD=62082\|UniProtKB=P35429	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021210.6\|UniProtKB=F1N0L3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034297.3\|UniProtKB=A0A287A5I8	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000040264.2\|UniProtKB=A0A337S481	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024175.1\|UniProtKB=A0A8I3PLY9	Canis lupus familiaris	O
XENLA\|Gene=hes2\|UniProtKB=Q00P32	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486138\|UniProtKB=A0A7D9NLV3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016162.2\|UniProtKB=Q1L7T8	Oryzias latipes	O
DANRE\|Gene=her7\|UniProtKB=A0A8M9PKJ6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013600.1\|UniProtKB=W5N810	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000022762.1\|UniProtKB=A0A3B3I1A2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004275.2\|UniProtKB=H2LH93	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060825-55\|UniProtKB=Q0P454	Danio rerio	O
DANRE\|Gene=hes2.1\|UniProtKB=A0A8M9QIL4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005083.1\|UniProtKB=W5MCL3	lepisosteus oculatus	O
HUMAN\|HGNC=26226\|UniProtKB=Q5TGS1	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000000081.3\|UniProtKB=H2PXW5	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000062876.1\|UniProtKB=A0A5F8AUD3	Macaca mulatta	O
MOUSE\|MGI=MGI=104877\|UniProtKB=Q61657	Mus musculus	O
RAT\|RGD=621339\|UniProtKB=Q04667	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000024525.4\|UniProtKB=E1B6Z2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000003370.4\|UniProtKB=F1RIM0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024724.3\|UniProtKB=F6SQL7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000045063.2\|UniProtKB=A0A337S964	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845023694.1\|UniProtKB=A0A8I3PTA9	Canis lupus familiaris	O
XENLA\|Gene=hes3.L\|UniProtKB=A0A1L8FMI2	Xenopus laevis	O
XENLA\|Gene=hes3.S\|UniProtKB=A0A1L8FGF0	Xenopus laevis	O
XENTR\|Gene=hes3\|UniProtKB=A0A8J0R195	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000024424.1\|UniProtKB=A0A3B3HJQ9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-204\|UniProtKB=Q90465	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005161.1\|UniProtKB=W5MCV7	lepisosteus oculatus	O
HUMAN\|HGNC=18254\|UniProtKB=Q96HZ4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043334.1\|UniProtKB=K7CZ00	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037768.1\|UniProtKB=A0A2I2Z5X2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000039992.2\|UniProtKB=A0A1D5Q114	Macaca mulatta	O
MOUSE\|MGI=MGI=1859852\|UniProtKB=Q9JHE6	Mus musculus	O
RAT\|RGD=1312047\|UniProtKB=A0A0G2K6W4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000054800.1\|UniProtKB=A0A3Q1LSS2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016342.5\|UniProtKB=F1SIU5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000028351.3\|UniProtKB=A0A3Q2HY31	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032525.3\|UniProtKB=A0A337S625	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029909.1\|UniProtKB=A0A8I3SCH4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000010642.4\|UniProtKB=A0A5F8GBG9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003062.2\|UniProtKB=F7A7W2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010025028.1\|UniProtKB=A0A8V1A1B5	Gallus gallus	O
XENLA\|Gene=hes6.1.S\|UniProtKB=A0A8J0VDG6	Xenopus laevis	O
XENLA\|Gene=hes6.1.L\|UniProtKB=A0A1L8GB50	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1018104\|UniProtKB=A0A8J0SUA0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016617.2\|UniProtKB=Q1L7T7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000015432.2\|UniProtKB=H2MKU9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050228-1\|UniProtKB=Q568A5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030828-5\|UniProtKB=Q6P0J1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004463.1\|UniProtKB=W5MAC3	lepisosteus oculatus	O
HUMAN\|HGNC=15977\|UniProtKB=Q9BYE0	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000008725.4\|UniProtKB=A0A2I3SKS5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005760.3\|UniProtKB=G3QSJ8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019851.4\|UniProtKB=F7GUV2	Macaca mulatta	O
MOUSE\|MGI=MGI=2135679\|UniProtKB=Q8BKT2	Mus musculus	O
RAT\|RGD=1305914\|UniProtKB=D3ZV20	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012436.6\|UniProtKB=E1BJY1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000060339.1\|UniProtKB=F1SSX6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013278.4\|UniProtKB=A0A9L0R1Z3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015190.6\|UniProtKB=M3WM48	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027731.1\|UniProtKB=A0A8I3QEJ3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000037945.1\|UniProtKB=A0A5F8G9J1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000046244.1\|UniProtKB=A0A6I8NGP0	Ornithorhynchus anatinus	O
XENLA\|Gene=LOC108703524\|UniProtKB=A0A8J0TUR8	Xenopus laevis	O
XENLA\|Gene=hes7.1-a\|UniProtKB=Q8UW74	Xenopus laevis	O
XENLA\|Gene=esr-5.L\|UniProtKB=Q9W7B6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6538723\|UniProtKB=A9UMI5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009833.2\|UniProtKB=H2M1Q6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-90\|UniProtKB=Q90467	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013605.1\|UniProtKB=W5N814	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000010016.2\|UniProtKB=H2M2C4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040824-4\|UniProtKB=Q6W4T8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-125\|UniProtKB=Q90463	Danio rerio	O
HUMAN\|HGNC=1046\|UniProtKB=O14503	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014571.5\|UniProtKB=H2R8H1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015864.3\|UniProtKB=G3RIG8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000056699.1\|UniProtKB=F7GRJ4	Macaca mulatta	O
MOUSE\|MGI=MGI=1097714\|UniProtKB=O35185	Mus musculus	O
RAT\|RGD=68439\|UniProtKB=O35780	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009863\|UniProtKB=Q5EA15	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000036136.3\|UniProtKB=A0A287BEM0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015069.3\|UniProtKB=F7BZS6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000034238.3\|UniProtKB=A0A2I2ULP5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845011295.1\|UniProtKB=A0A8I3RWF0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004516.4\|UniProtKB=F6UR97	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000038785.1\|UniProtKB=A0A6I8PGG5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021719.1\|UniProtKB=A0A8V0ZLK4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012577.3\|UniProtKB=G1KMI4	Anolis carolinensis	O
XENLA\|Gene=bhlhe40.L\|UniProtKB=A0A8J0V2L1	Xenopus laevis	O
XENLA\|Gene=bhlhe40.S\|UniProtKB=A0A8J0V3U2	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000035212\|UniProtKB=A0A6I8SKW8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000022966.1\|UniProtKB=Q2L4U5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000014397.2\|UniProtKB=Q2L4U4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-3133\|UniProtKB=Q0D311	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010962.1\|UniProtKB=W5MYJ1	lepisosteus oculatus	O
HUMAN\|HGNC=24149\|UniProtKB=Q9HCC6	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000023647.3\|UniProtKB=H2R3T5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013399.3\|UniProtKB=G3RC48	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001817.3\|UniProtKB=F7GS86	Macaca mulatta	O
BOVIN\|Ensembl=ENSBTAG00000014705.5\|UniProtKB=E1BP65	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000035420.2\|UniProtKB=A0A287AS85	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000028788.3\|UniProtKB=A0A3Q2HNH6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000046395.2\|UniProtKB=A0A337SI62	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020212.1\|UniProtKB=A0A8I3PC06	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000018647.4\|UniProtKB=H9H763	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049111.1\|UniProtKB=A0A6I8NWR2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021466.1\|UniProtKB=Q6XLQ0	Gallus gallus	O
CHICK\|Gene=HES1\|UniProtKB=O57337	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000001611.4\|UniProtKB=H9G5B5	Anolis carolinensis	O
XENLA\|Gene=hes4-a\|UniProtKB=Q90Z12	Xenopus laevis	O
XENLA\|Gene=hes4-b\|UniProtKB=Q90VV1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-487830\|UniProtKB=Q6PBD4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000028869.1\|UniProtKB=Q1L7T3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000005453.2\|UniProtKB=H2LLF4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-011213-1\|UniProtKB=Q9DF41	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007298.1\|UniProtKB=W5MKD0	lepisosteus oculatus	O
ORNAN\|Ensembl=ENSOANG00000011082.3\|UniProtKB=F7FD37	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024997.1\|UniProtKB=A0A8V1A177	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002708.4\|UniProtKB=G1KB25	Anolis carolinensis	O
XENLA\|Gene=hes6.2.L\|UniProtKB=A0A1L8GBF1	Xenopus laevis	O
XENLA\|Gene=hes6.2.S\|UniProtKB=A0A1L8G532	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-479404\|UniProtKB=Q0VFM2	Xenopus tropicalis	O
DANRE\|ZFIN=ZDB-GENE-030131-2376\|UniProtKB=F1QI81	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014036.1\|UniProtKB=W5N9J2	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000015428.2\|UniProtKB=H2MKT8	Oryzias latipes	O
DANRE\|Gene=her8.2\|UniProtKB=A0A8M1NTZ6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004481.1\|UniProtKB=W5MAE4	lepisosteus oculatus	O
HUMAN\|HGNC=5192\|UniProtKB=Q14469	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000045020.1\|UniProtKB=H2QNZ9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008521.3\|UniProtKB=G3QZL7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000058672.1\|UniProtKB=I2CUI4	Macaca mulatta	O
MOUSE\|MGI=MGI=104853\|UniProtKB=P35428	Mus musculus	O
RAT\|RGD=62081\|UniProtKB=Q04666	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000569\|UniProtKB=Q3ZBG4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000031356.3\|UniProtKB=A0A287AUT4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000026945.3\|UniProtKB=F6PTK2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000026945.3\|UniProtKB=F6PTK2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000042282.2\|UniProtKB=A0A337SWV8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025905.1\|UniProtKB=A0A8I3PRN5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000043132.1\|UniProtKB=A0A5F8HCQ7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000039736.1\|UniProtKB=A0A6I8N7Q4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010014807.1\|UniProtKB=R4GJE0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004091.3\|UniProtKB=H9G8H9	Anolis carolinensis	O
XENLA\|Gene=hes7.2.S\|UniProtKB=A0A8J0U211	Xenopus laevis	O
XENLA\|Gene=hes7.2.L\|UniProtKB=A0A1L8H3L7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-486482\|UniProtKB=Q4W593	Xenopus tropicalis	O
XENLA\|Gene=hes1-b\|UniProtKB=Q8AVU4	Xenopus laevis	O
XENLA\|Gene=hes1-a\|UniProtKB=Q6IRB2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-487995\|UniProtKB=Q5PPM5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000007556.2\|UniProtKB=Q1L7T4	Oryzias latipes	O
DANRE\|Gene=LOC108180270\|UniProtKB=A0A8M9PT25	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-144\|UniProtKB=Q6PBX3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004988.1\|UniProtKB=W5MC94	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000013835.2\|UniProtKB=F6QL93	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005021.3\|UniProtKB=F6TXK6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000003929.3\|UniProtKB=F7A592	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_267120\|UniProtKB=C3YR42	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_127513\|UniProtKB=C3YR36	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431117\|UniProtKB=A0A9J7MF95	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429950\|UniProtKB=A0A9J7MC70	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423383\|UniProtKB=A0A9J7LRK4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432552\|UniProtKB=A0A9J7MH47	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429947\|UniProtKB=A0A9J7M966	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431118\|UniProtKB=A0A9J7MBQ5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430276\|UniProtKB=A0A9J7M9L4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC592057\|UniProtKB=A0A7M7RIK0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC752043\|UniProtKB=A0A7M7SZQ6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC581970\|UniProtKB=A0A7M7RER1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_414294\|UniProtKB=A0A7M6UQE8	Strongylocentrotus purpuratus	O
CAEBR\|WormBase=WBGene00026235\|UniProtKB=A8WUV4	Caenorhabditis briggsae	LDO
TRICA\|EnsemblGenome=TC011804\|UniProtKB=D6WZN3	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG172587\|UniProtKB=T1F5K1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG177336\|UniProtKB=T1FBI9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG175137\|UniProtKB=T1F8W9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG177346\|UniProtKB=T1FBJ4	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG177333\|UniProtKB=T1FBI6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG177334\|UniProtKB=T1FBI7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG162289\|UniProtKB=T1ESG6	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204200\|UniProtKB=A7RYX5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241656\|UniProtKB=A7RYX4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241655\|UniProtKB=A7RYX3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g202232\|UniProtKB=A7RU73	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g242121\|UniProtKB=A7S155	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98450\|UniProtKB=A7RYX7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g164325\|UniProtKB=A7RYX2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g242118\|UniProtKB=A7S152	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g67328\|UniProtKB=A7RYX6	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG59292\|UniProtKB=B3S5D9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57355\|UniProtKB=B3RZ77	Trichoplax adhaerens	O
EREGS\|EnsemblGenome=AGOS_ADL123C\|UniProtKB=Q75AP3	Eremothecium gossypii	O
EMENI\|EnsemblGenome=ANIA_08271\|UniProtKB=C8V3P3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G04190\|UniProtKB=Q4WEU1	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_02811\|UniProtKB=Q5B9G9	Emericella nidulans	O
CHLRE\|EnsemblGenome=CHLRE_14g609700v5\|UniProtKB=A0A2K3CX93	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g401400v5\|UniProtKB=A0A2K3DCS8	Chlamydomonas reinhardtii	O