PANTHER Gene Information

Gene Symbol(s):

DEGS2

Organism:

Pan troglodytes

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Gene Name:

sphingolipid 4-desaturase

Gene ID:

ENSPTRG00000006716.5

Protein ID:

H2Q8X2

Persistent Id:

PTN000306168

Alternate Ids:

H2Q8X2_PANTR(UniProtKB-ID)	H2Q8X2(Synonym)
ENSPTRG00000006716(Ensembl)	ENSPTRT00000012366(Ensembl_TRS)
AC192208(EMBL)	ENSPTRP00000011449(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 (PTHR12879)
PANTHER Subfamily:	SPHINGOLIPID DELTA(4)-DESATURASE_C4-MONOOXYGENASE DES2 (PTHR12879:SF21)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
PANTHER GO-slim Biological Process:	ceramide biosynthetic process alcohol metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydroxylase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	oxidoreductase activity, sphingolipid delta-4 desaturase activity
GO BP Complete:	lipid metabolic process, ceramide biosynthetic process, sphinganine metabolic process, sphingolipid biosynthetic process
GO CC Complete:	endoplasmic reticulum membrane, membrane, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20113\|UniProtKB=Q6QHC5	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000005888.3\|UniProtKB=G3QSW4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000062581.1\|UniProtKB=A0A5F7ZY35	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917309\|UniProtKB=Q8R2F2	Mus musculus	LDO
RAT\|RGD=1305023\|UniProtKB=Q564G3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009294\|UniProtKB=Q0II71	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000002512.5\|UniProtKB=F1SAQ0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023383.3\|UniProtKB=F6VWM0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025331.4\|UniProtKB=M3X226	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004234.1\|UniProtKB=A0A8I3MVV0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000044302.1\|UniProtKB=A0A5F8GGF3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012424.3\|UniProtKB=F7DKC9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016561.1\|UniProtKB=A0A8V0YWS9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011491.4\|UniProtKB=H9GHN5	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000013396.4\|UniProtKB=H9GJV9	Anolis carolinensis	LDO
XENLA\|Gene=degs3.S\|UniProtKB=A0A8J0TH86	Xenopus laevis	O
XENLA\|Gene=degs3.L\|UniProtKB=Q7SYZ6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5801015\|UniProtKB=F6Z7D6	Xenopus tropicalis	O
XENLA\|Gene=degs2.L\|UniProtKB=Q6AZN7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-977920\|UniProtKB=A0A8J0QPB4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000025055.1\|UniProtKB=A0A3B3H642	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-080228-1\|UniProtKB=F1QW74	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011633.1\|UniProtKB=W5N0Y4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009936.3\|UniProtKB=F6R614	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018489.1\|UniProtKB=H2XM50	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118407735\|UniProtKB=A0A9J7KKW4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408386\|UniProtKB=A0A9J7KLK3	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118427795\|UniProtKB=A0A9J7M398	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427793\|UniProtKB=A0A9J7M389	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587766\|UniProtKB=A0A7M7RGW1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00017996\|UniProtKB=O44186	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00028296\|UniProtKB=A8X1A2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00104452\|UniProtKB=A0A2A6BVM8	Pristionchus pacificus	LDO
CAEEL\|WormBase=WBGene00013197\|UniProtKB=G5EC63	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00030495\|UniProtKB=A8X7B7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00105823\|UniProtKB=A0A2A6CT66	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0001941\|UniProtKB=Q94515	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011402\|UniProtKB=Q7Q2Y9	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012111\|UniProtKB=A0A1S4H8G3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015856\|UniProtKB=D2A4B6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_48184\|UniProtKB=E9GB97	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010259\|UniProtKB=B7PYU9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG188309\|UniProtKB=T1FPV0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG66489\|UniProtKB=T1FYM1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g193358\|UniProtKB=A7STF5	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g174147\|UniProtKB=A7STF3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG50675\|UniProtKB=B3S589	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_9500\|UniProtKB=A9V3C6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38045\|UniProtKB=A9V5D6	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_AGR025W\|UniProtKB=Q750D0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000198792\|UniProtKB=Q5AJX2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D06237g\|UniProtKB=Q6CA36	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_04405\|UniProtKB=Q5B4X5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G06940\|UniProtKB=Q4WNU0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08927\|UniProtKB=Q1K6J1	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_10642\|UniProtKB=A7EZ76	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_05241\|UniProtKB=Q0USM3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC3B8.07c\|UniProtKB=O59715	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01057\|UniProtKB=B6JXD0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA06240\|UniProtKB=Q5KNJ8	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02651\|UniProtKB=A0A0D1E4C3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07554\|UniProtKB=E3KDE8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_3349\|UniProtKB=F4P3E1	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0269738\|UniProtKB=Q55D94	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_155619\|UniProtKB=F0ZUH0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_26_1700\|UniProtKB=Q4Q923	Leishmania major	LDO
LEIMA\|EnsemblGenome=LMJF_26_1670\|UniProtKB=Q4Q925	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.6.3000\|UniProtKB=Q583N4	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00027264001\|UniProtKB=A0EHZ6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017857001\|UniProtKB=A0DKG0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020602001\|UniProtKB=A0DV71	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00022121001\|UniProtKB=A0E0Y5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_10677\|UniProtKB=B8CE76	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_32145\|UniProtKB=B8BUG3	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GA06_PHYRM\|UniProtKB=H3GA06	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00009p00266200\|UniProtKB=W1NJ76	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_8G01130\|UniProtKB=A0A0K9NLJ6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g19510\|UniProtKB=A0A804L9M4	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma11_g03900\|UniProtKB=A0A804L3Z4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_010250mg\|UniProtKB=K3Y7Q9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G157100\|UniProtKB=C5YCK8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb075800\|UniProtKB=A0A1D6E4U5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0639600\|UniProtKB=Q6H5U3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_5g16510v3\|UniProtKB=I1IZY6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0183780\|UniProtKB=A0A8I7B3I5	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2B02G389900\|UniProtKB=A0A3B6C9P7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G372900\|UniProtKB=A0A3B6B367	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G369100\|UniProtKB=A0A2X0S8S0	Triticum aestivum	LDO
NELNU\|Gene=LOC104587162\|UniProtKB=A0A1U7YRX3	Nelumbo nucifera	O
NELNU\|Gene=LOC104586429\|UniProtKB=A0A1U7YSF4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110802441\|UniProtKB=A0A9R0J9A5	Spinacia oleracea	LDO
LACSA\|Gene_ORFName=LSAT_V11C100048900\|UniProtKB=A0A9R1WQR4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009682mg\|UniProtKB=A0A022QND1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_24978\|UniProtKB=A0A2G2YJF8	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400022827\|UniProtKB=M1C392	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g009030.3\|UniProtKB=A0A3Q7IBP0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107807159\|UniProtKB=A0A1S4BDH2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107808948\|UniProtKB=A0A1S4BJE5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107806069\|UniProtKB=A0A1S4B9S2	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi10g00414\|UniProtKB=F6HD78	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E03124\|UniProtKB=A0A059C8F2	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra029531\|UniProtKB=M4EL64	Brassica campestris	LDO
ARATH\|TAIR=locus=2135388\|UniProtKB=Q9ZPH4	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107963502\|UniProtKB=A0A1U8PYQ2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107900374\|UniProtKB=A0A1U8ITT3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107937759\|UniProtKB=A0A1U8MHC4	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107925278\|UniProtKB=A0A1U8LE17	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_025198\|UniProtKB=A0A061EZH2	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_029899\|UniProtKB=A0A061GEJ7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g020224mg\|UniProtKB=A0A067G8D5	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_011G050800v3\|UniProtKB=A0A2K1YFS0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G026000\|UniProtKB=A0A2C9U8D3	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_17G043900\|UniProtKB=A0A2C9U5Q5	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0935980\|UniProtKB=B9RZ74	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G240700\|UniProtKB=I1M269	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G072800\|UniProtKB=C6TIK0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g013070\|UniProtKB=A2Q4Q7	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr03_07040\|UniProtKB=A0A2I4ELC7	Juglans regia	O
JUGRE\|EnsemblGenome=Jr04_17140\|UniProtKB=A0A2I4GWP4	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G073750\|UniProtKB=A0A0A0LSB9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G044600\|UniProtKB=M5WTY1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_77748\|UniProtKB=D8QRG3	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_94775\|UniProtKB=D8RJD8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c23_19370\|UniProtKB=A0A2K1IK09	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0083s0054\|UniProtKB=A0A2R6WJU1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003880080\|UniProtKB=A0A1Y1IGS2	Klebsormidium nitens	LDO
GLOVI\|Gene=Q7NHN4_GLOVI\|UniProtKB=Q7NHN4	Gloeobacter violaceus	LDO
BRADU\|Gene=Q89CD6_BRADU\|UniProtKB=Q89CD6	Bradyrhizobium diazoefficiens	LDO