PANTHER Gene Information

Gene Symbol(s):

EIF(ISO)4E

Organism:

Arabidopsis thaliana

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Gene Name:

Eukaryotic translation initiation factor isoform 4E

Gene ID:

2165892

Protein ID:

O04663

Persistent Id:

PTN000238888

Alternate Ids:

AAK96821(EMBL-CDS)	U62044(EMBL)
Q9SAN8(AltAccession)	EIF(ISO)4E(Symbol)
12644043(GI)	eIF4Eiso protein(Synonym)
locus:2165892(TAIR)	833534(GeneID)
IF4E4_ARATH(UniProtKB-ID)	AT5G35620(Ensembl)
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PANTHER Classification

PANTHER Family:	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED (PTHR11960)
PANTHER Subfamily:	EUKARYOTIC TRANSLATION INITIATION FACTOR ISOFORM 4E (PTHR11960:SF67)
PANTHER GO-slim Molecular Function:	translation initiation factor activity RNA cap binding
PANTHER GO-slim Biological Process:	translational initiation
PANTHER GO-slim Cellular Component:	cytoplasm intracellular protein-containing complex
PANTHER protein class:	translation initiation factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	translation initiation factor activity, RNA 7-methylguanosine cap binding, protein binding
GO BP Complete:	translational initiation, response to virus, negative regulation of defense response to virus
GO CC Complete:	nucleus, eukaryotic translation initiation factor 4F complex, cytoplasm, plastid

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=33179\|UniProtKB=A6NMX2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000028481.4\|UniProtKB=A0A2J8J5W2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015854.3\|UniProtKB=G3RMR3	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=2685119\|UniProtKB=Q3UTA9	Mus musculus	O
RAT\|RGD=15003615\|UniProtKB=A0A8I6A3E5	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000003103.6\|UniProtKB=F1N030	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000014052.5\|UniProtKB=F1S3A3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000050191.1\|UniProtKB=A0A3Q2KPI1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000003074.6\|UniProtKB=M3VZN5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845012098.1\|UniProtKB=A0A8I3NKV8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005097.3\|UniProtKB=F6ZEI9	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000016941.3\|UniProtKB=F6VMH3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000041010.1\|UniProtKB=A0A5F8HAM8	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010010130.1\|UniProtKB=A0A8V0YCN6	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007055.4\|UniProtKB=H9GC84	Anolis carolinensis	O
XENLA\|Gene=LOC108710984\|UniProtKB=A0A8J0UTN9	Xenopus laevis	O
XENLA\|Gene=LOC108713228\|UniProtKB=A0A1L8GUZ9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6258261\|UniProtKB=A0A6I8PTW7	Xenopus tropicalis	O
PANTR\|Ensembl=ENSPTRG00000047631.1\|UniProtKB=A0A2I3T7Y8	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000022832.2\|UniProtKB=A0A2I2ZX18	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000050078.1\|UniProtKB=A0A2I3RHS9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000036744.1\|UniProtKB=A0A2I2ZUE8	Gorilla gorilla gorilla	O
HUMAN\|HGNC=3287\|UniProtKB=P06730	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016301.6\|UniProtKB=G2HH86	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037188.1\|UniProtKB=A0A2I2ZX68	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000004718.3\|UniProtKB=G3S841	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011066.4\|UniProtKB=H9ENS9	Macaca mulatta	O
MOUSE\|MGI=MGI=95305\|UniProtKB=P63073	Mus musculus	O
RAT\|RGD=150343909\|UniProtKB=A0A8I6G664	Rattus norvegicus	O
RAT\|RGD=69647\|UniProtKB=P63074	Rattus norvegicus	O
BOVIN\|Gene=EIF4E\|UniProtKB=Q9N0T5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000009522.6\|UniProtKB=A0A3Q1NEI6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005040455.1\|UniProtKB=A0A4X1UC72	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006472.4\|UniProtKB=A0A9L0S9Y6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000009949.6\|UniProtKB=A0A337S7Q3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027781.1\|UniProtKB=A0A8I3Q422	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845023892.1\|UniProtKB=A0A8I3S7T5	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845030609.1\|UniProtKB=A0A8I3QYF5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000020716.4\|UniProtKB=F7BAD4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013092.3\|UniProtKB=F6YID3	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000009633.4\|UniProtKB=A0A6I8NMU5	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010004584.1\|UniProtKB=A0A8V0XMZ0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000039528.1\|UniProtKB=A0A803T9Q0	Anolis carolinensis	O
XENLA\|Gene=eif4e1b.S\|UniProtKB=A0A8J0TKX6	Xenopus laevis	O
XENLA\|Gene=eif4e.L\|UniProtKB=Q5HZ86	Xenopus laevis	O
XENLA\|Gene=eif4e\|UniProtKB=P48597	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-855435\|UniProtKB=Q28CE6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000019400.2\|UniProtKB=H2MYQ2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050417-398\|UniProtKB=B8A6A1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009334.1\|UniProtKB=W5MSN2	lepisosteus oculatus	O
DANRE\|ZFIN=ZDB-GENE-980526-127\|UniProtKB=Q9PW28	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011832.1\|UniProtKB=W5N1P4	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000017636.2\|UniProtKB=H2MTG9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000020641.2\|UniProtKB=A0A3B3HI18	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041121-14\|UniProtKB=Q5RKQ5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040413-1\|UniProtKB=Q9DFS6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012198.1\|UniProtKB=W5N300	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004199.3\|UniProtKB=F7B4V3	Ciona intestinalis	O
BRAFL\|Gene=LOC118422780\|UniProtKB=A0A9J7LPK0	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_120045\|UniProtKB=C3Y029	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_100048986\|UniProtKB=A3KLJ2	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00002060\|UniProtKB=Q21693	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00030038\|UniProtKB=A8X610	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00030023\|UniProtKB=A8X5Z5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00002063\|UniProtKB=P56570	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00002059\|UniProtKB=O45551	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00042429\|UniProtKB=A8WKD2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00205570\|UniProtKB=A0A2A6B5E0	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00002061\|UniProtKB=O61955	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06370\|UniProtKB=A8X231	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00277389\|UniProtKB=A0A2A6CA80	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00283275\|UniProtKB=A0A454XIY4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116897\|UniProtKB=A0A454XW88	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0039622\|UniProtKB=Q9VAR1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0265089\|UniProtKB=Q9VSG1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0035823\|UniProtKB=Q9VSB6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0040368\|UniProtKB=Q9W5B3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0015218\|UniProtKB=P48598	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0035709\|UniProtKB=Q9VRY0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007172\|UniProtKB=A7URN4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013759\|UniProtKB=D6WJL4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_98425\|UniProtKB=E9G3M7	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021213\|UniProtKB=B7Q942	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG163185\|UniProtKB=T1ETS0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG112394\|UniProtKB=T1EFJ5	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196099\|UniProtKB=A7REQ6	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG28470\|UniProtKB=B3S4N9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_33032\|UniProtKB=A9V342	Monosiga brevicollis	O
YEAST\|SGD=S000005499\|UniProtKB=P07260	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL188C\|UniProtKB=Q75AV8	Eremothecium gossypii	O
CANAL\|CGD=CAL0000195194\|UniProtKB=Q9P975	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D24299g\|UniProtKB=Q6C7Y7	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03411\|UniProtKB=Q5B7R9	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G01480\|UniProtKB=Q4WAJ0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02076\|UniProtKB=Q7SEY8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04707\|UniProtKB=A7EHB5	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00754\|UniProtKB=Q0V5G0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC1709.18\|UniProtKB=O74743	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03223\|UniProtKB=B6K3N3	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC16E8.15\|UniProtKB=P78954	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00507\|UniProtKB=B6JVU1	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNB04220\|UniProtKB=Q5KLS6	Cryptococcus neoformans	O
PUCGT\|EnsemblGenome=PGTG_13360\|UniProtKB=E3KS66	Puccinia graminis	O
CRYNJ\|EnsemblGenome=CNC03200\|UniProtKB=Q5KKF3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_06377\|UniProtKB=A0A0D1DT13	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_15366\|UniProtKB=E3KZI5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_25777\|UniProtKB=F4P5K8	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_040280\|UniProtKB=C4M2F7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_151820\|UniProtKB=B1N2F5	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_159690\|UniProtKB=C4LX49	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_196930\|UniProtKB=C4LVB1	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_013220\|UniProtKB=C4LX88	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_158040\|UniProtKB=C4M2C3	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_030090\|UniProtKB=C4M443	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_180000\|UniProtKB=C4M651	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0291820\|UniProtKB=Q54E38	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149786\|UniProtKB=F0ZEN5	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0270910\|UniProtKB=B0G0Z1	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149749\|UniProtKB=F0ZEK2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0284841\|UniProtKB=Q54P37	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_99410\|UniProtKB=F0ZZ02	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0268574\|UniProtKB=Q55FE0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_41544\|UniProtKB=F1A0A9	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_19_1480\|UniProtKB=Q4QD60	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.61.0210\|UniProtKB=Q387Q8	Trypanosoma brucei	O
GIAIC\|Gene_ORFName=GL50803_0096264\|UniProtKB=A0A644F4S5	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_14482\|UniProtKB=D3KH44	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_553430\|UniProtKB=A2GAV4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_179740\|UniProtKB=A2F456	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_379750\|UniProtKB=A2E7K0	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_079410\|UniProtKB=A2EF73	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_257620\|UniProtKB=A2F4E3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_479590\|UniProtKB=A2FLM1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_269010\|UniProtKB=A2EG14	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_121790\|UniProtKB=A2E990	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_307000\|UniProtKB=A2FTY7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_108990\|UniProtKB=A2F040	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0111800\|UniProtKB=B9ZSJ0	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_0315100\|UniProtKB=O97266	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00034638001\|UniProtKB=A0C2Z3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027724001\|UniProtKB=A0BDS7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00033550001\|UniProtKB=A0BYT0	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_261607\|UniProtKB=B8BW12	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_40798\|UniProtKB=B8C3D4	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GM50_PHYRM\|UniProtKB=H3GM50	Phytophthora ramorum	O
PHYRM\|Gene=H3GXG5_PHYRM\|UniProtKB=H3GXG5	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_03g199900v5\|UniProtKB=A8IXR5	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00067p00203630\|UniProtKB=U5D018	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_393G00100\|UniProtKB=A0A0K9P4D4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g12700\|UniProtKB=A0A804J3S5	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g31560\|UniProtKB=A0A804IW52	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_037504mg\|UniProtKB=K4AF47	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G224400\|UniProtKB=C5WZC3	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb046430\|UniProtKB=B6T1D2	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb222060\|UniProtKB=O81482	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0467600\|UniProtKB=P48600	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g28340v3\|UniProtKB=I1I4J9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0041260\|UniProtKB=F2D7Z6	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G167100\|UniProtKB=A0A3B5YVA7	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G149200\|UniProtKB=A0A3B5XZ03	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCLE_scaffold_070407_01G000200\|UniProtKB=Q03389	Triticum aestivum	LDO
NELNU\|Gene=LOC104602795\|UniProtKB=A0A1U8AQF7	Nelumbo nucifera	LDO
BRANA\|Gene_ORFName=DARMORV10_A05P16480.1\|UniProtKB=A0A078HJC6	Brassica napus	O
BRACM\|EnsemblGenome=Bra039484\|UniProtKB=D9ZJL9	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00092906001\|UniProtKB=A0A078IIY3	Brassica napus	O
BRACM\|EnsemblGenome=Bra035531\|UniProtKB=A0A385LJX8	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C04P43290.1\|UniProtKB=A0A078H757	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra035393\|UniProtKB=A0A385LJW9	Brassica campestris	LDO
JUGRE\|EnsemblGenome=Jr07_22510\|UniProtKB=A0A2I4DSE0	Juglans regia	LDO
SELML\|EnsemblGenome=SELMODRAFT_125743\|UniProtKB=D8SVJ0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_119068\|UniProtKB=D8SJX5	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c1_5840\|UniProtKB=A0A2K1L6Z8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_32310\|UniProtKB=A9U1W7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c1_5850\|UniProtKB=A9S3L2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c11_1600\|UniProtKB=A9S0E0	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0005s0006\|UniProtKB=A0A2R6XQE2	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000810310\|UniProtKB=A0A1Y1HS84	Klebsormidium nitens	O