PANTHER Gene Information

Gene Symbol(s):

Organism:

Drosophila melanogaster

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Gene Name:

Paired box protein Pax-6

Gene ID:

FBgn0005558

Protein ID:

O18381

Persistent Id:

PTN000676691

Alternate Ids:

AAM17964(EMBL-CDS)	X79493(EMBL)
Q9V4F5(AltAccession)	2511636(GI)
Protein eyeless(Synonym)	PAX6_DROME(UniProtKB-ID)
FBgn0005558(FlyBase)	FBgn0005558(Ensembl)
ey(Symbol)	43812(GeneID)
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PANTHER Classification

PANTHER Family:	PAIRED BOX PROTEIN PAX-6-RELATED-RELATED (PTHR45636)
PANTHER Subfamily:	PAIRED BOX PROTEIN PAX-6-RELATED (PTHR45636:SF41)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	anatomical structure development regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	photoreceptor cell fate specification, mushroom body development, neuron differentiation, positive regulation of cell population proliferation, regulation of DNA-templated transcription, eye-antennal disc morphogenesis, brain morphogenesis, brain development, regulation of insulin-like growth factor receptor signaling pathway, positive regulation of transcription by RNA polymerase II, compound eye development, sensory organ development, positive regulation of multicellular organism growth, regulation of transcription by RNA polymerase II, glial cell migration, adult walking behavior, positive regulation of cell growth, compound eye morphogenesis, positive regulation of DNA-templated transcription, central complex development, glucose homeostasis
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
ORNAN\|Ensembl=ENSOANG00000038288.1\|UniProtKB=A0A6I8N991	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000013797.4\|UniProtKB=G1KP91	Anolis carolinensis	O
XENLA\|Gene=Pax10b\|UniProtKB=V5ZDY3	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000032534\|UniProtKB=A0A6I8PLT9	Xenopus tropicalis	O
HUMAN\|HGNC=8618\|UniProtKB=O43316	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019653.6\|UniProtKB=H2QVB3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002555.3\|UniProtKB=G3QJC4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000015429.4\|UniProtKB=F6Q449	Macaca mulatta	O
MOUSE\|MGI=MGI=97488\|UniProtKB=P32115	Mus musculus	O
RAT\|RGD=620433\|UniProtKB=O88436	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000410.6\|UniProtKB=A0A3Q1LVW0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016591.5\|UniProtKB=A0A4X1W119	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000008343.4\|UniProtKB=F6TZD6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005485.5\|UniProtKB=A0A5F5XW36	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025704.1\|UniProtKB=A0A8I3PW34	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000000819.3\|UniProtKB=F6PL25	Ornithorhynchus anatinus	O
HUMAN\|HGNC=8620\|UniProtKB=P26367	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000010246.3\|UniProtKB=A0A2I2ZFV9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016810.4\|UniProtKB=H9FV32	Macaca mulatta	O
MOUSE\|MGI=MGI=97490\|UniProtKB=P63015	Mus musculus	O
RAT\|RGD=3258\|UniProtKB=P63016	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004561\|UniProtKB=Q1LZF1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000013320.5\|UniProtKB=A0A8D0V8S9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021000.3\|UniProtKB=A0A9L0RRN8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000038150.3\|UniProtKB=M3W733	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027665.1\|UniProtKB=A0A8I3QEP3	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000015149.3\|UniProtKB=A0A6I8NU24	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010006271.1\|UniProtKB=A0A8V0XXN4	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023642.1\|UniProtKB=A0A8V0ZNJ7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002252.4\|UniProtKB=A0A803TIT1	Anolis carolinensis	O
XENLA\|Gene=LOC108710280\|UniProtKB=A0A8J1MKE4	Xenopus laevis	O
XENLA\|Gene=pax6.L\|UniProtKB=A0A1L8GJ29	Xenopus laevis	O
XENLA\|Gene=pax6.S\|UniProtKB=A0A1L8GDT8	Xenopus laevis	O
XENLA\|Gene=pax6\|UniProtKB=P55864	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-484088\|UniProtKB=A0A6I8SL27	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015177.2\|UniProtKB=A0A3B3H273	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041210-244\|UniProtKB=G2ZGB0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015535.1\|UniProtKB=W5NER2	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000000847.2\|UniProtKB=A0A3B3HSU6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000009913\|UniProtKB=O73917	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-001031-1\|UniProtKB=A0A0R4IQL7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-990415-200\|UniProtKB=P26630	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004578.1\|UniProtKB=W5MAS4	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000005977.3\|UniProtKB=F6VTF7	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006503.3\|UniProtKB=F6PW95	Ciona intestinalis	O
BRAFL\|Gene=LOC118410848\|UniProtKB=A0A9J7KQW7	Branchiostoma floridae	O
BRAFL\|Gene=Pax6\|UniProtKB=O61988	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_373405\|UniProtKB=O16802	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918459\|UniProtKB=A0A7M7SW42	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC583610\|UniProtKB=A0A7M7RI14	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC574563\|UniProtKB=A0A7M7ND11	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892714\|UniProtKB=A0A7M7P7W6	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00013147\|UniProtKB=O01996	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024319\|UniProtKB=A8WP29	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109853\|UniProtKB=A0A2A6CUV4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006870\|UniProtKB=G5EDS1	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04481\|UniProtKB=A8WXS7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00305123\|UniProtKB=A0A8R1Z3L2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092996\|UniProtKB=A0A2A6CU56	Pristionchus pacificus	O
ANOGA\|EnsemblGenome=AGAP000057\|UniProtKB=Q7QEM0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP000067\|UniProtKB=A0A1S4G8I5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003570\|UniProtKB=A0A139WLD9	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC032832\|UniProtKB=A0A139WJJ9	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC007409\|UniProtKB=A0A139WJ10	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_249991\|UniProtKB=E9GXP3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_249978\|UniProtKB=E9GXN4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_122807\|UniProtKB=E9I580	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021772\|UniProtKB=B7Q4S0	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW006352\|UniProtKB=B7PL66	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG173449\|UniProtKB=T1F6U6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG80374\|UniProtKB=T1G400	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243681\|UniProtKB=A7S916	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g239535\|UniProtKB=A7RN74	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG3502\|UniProtKB=B3S644	Trichoplax adhaerens	O