PANTHER Gene Information   
Gene Symbol(s): pmk-3
Organism: Caenorhabditis elegans
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Gene Name: Mitogen-activated protein kinase pmk-3
Gene ID: WBGene00004057
Protein ID: O44514
Persistent Id: PTN000622499
Alternate Ids:
WBGene00004057(WormBase) 351065436(GI)
F42G8.4a(WormBase_TRS) CE29318(WormBase_PRO)
Stress-activated protein kinase pmk-3(Synonym) F42G8.4a(Ensembl_PRO)
F42G8.4a(Ensembl_TRS) pmk-3(Symbol)
FO080126(EMBL) CCD61404(EMBL-CDS)
2.7.11.24(EC) WBGene00004057(Ensembl)
PMK3_CAEEL(UniProtKB-ID) NP_501363(refSeq)
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PANTHER Classification
PANTHER Family: MITOGEN-ACTIVATED PROTEIN KINASE (PTHR24055)
PANTHER Subfamily: MITOGEN-ACTIVATED PROTEIN KINASE PMK-3 (PTHR24055:SF155)  
PANTHER GO-slim Molecular Function: protein serine/threonine kinase activity
PANTHER GO-slim Biological Process: intracellular signal transduction
PANTHER GO-slim Cellular Component: cytoplasm
nucleus
PANTHER protein class: non-receptor serine/threonine protein kinase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, protein kinase binding, MAP kinase activity, protein kinase activity, protein serine/threonine kinase activity, kinase activity, protein serine kinase activity
GO BP Complete: MAPK cascade, positive regulation of axon extension involved in regeneration, behavioral response to nicotine, p38MAPK cascade, regulation of axon extension involved in axon guidance, regulation of synapse organization, response to osmotic stress, regulation of 3'-UTR-mediated mRNA stabilization, protein phosphorylation, axon regeneration, intracellular signal transduction
GO CC Complete: nucleus, dendrite, cytoplasm, cilium, cell projection, axon
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by NTRKs, TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Platelet homeostasis, MAPK targets/ Nuclear events mediated by MAP kinases, TRIF(TICAM1)-mediated TLR4 signaling , ERK/MAPK targets, Signaling by Receptor Tyrosine Kinases, Negative regulation of MAPK pathway, Cellular responses to stimuli, RAF/MAP kinase cascade, NOD1/2 Signaling Pathway, Toll Like Receptor 4 (TLR4) Cascade, MyD88:MAL(TIRAP) cascade initiated on plasma membrane, VEGFA-VEGFR2 Pathway, MAP kinase activation, Toll Like Receptor 2 (TLR2) Cascade, ADP signalling through P2Y purinoceptor 1, Signaling by Interleukins, Signal amplification, p38MAPK events, Toll Like Receptor 3 (TLR3) Cascade, MAPK1/MAPK3 signaling, Signalling to ERKs, MyD88 dependent cascade initiated on endosome, MyD88 cascade initiated on plasma membrane, Signal Transduction, Innate Immune System, Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, Signaling by VEGF, Developmental Biology, Activation of the AP-1 family of transcription factors, Interleukin-17 signaling, Myogenesis, Toll Like Receptor TLR1:TLR2 Cascade, Immune System, Signalling to RAS, Toll Like Receptor 5 (TLR5) Cascade, Platelet activation, signaling and aggregation, Hemostasis, Signaling by NTRK1 (TRKA), Platelet sensitization by LDL, Cellular responses to stress, MAPK family signaling cascades, Oxidative Stress Induced Senescence, Toll-like Receptor Cascades, Toll Like Receptor 9 (TLR9) Cascade, Cellular Senescence, activated TAK1 mediates p38 MAPK activation, Toll Like Receptor 7/8 (TLR7/8) Cascade, Neutrophil degranulation, Cytokine Signaling in Immune system, MyD88-independent TLR4 cascade , Nuclear Events (kinase and transcription factor activation), Toll Like Receptor TLR6:TLR2 Cascade, Toll Like Receptor 10 (TLR10) Cascade

Orthologs