PANTHER Gene Information

Gene Symbol(s):

ZK697.8

Organism:

Caenorhabditis elegans

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Gene Name:

Probable 5-hydroxyisourate hydrolase ZK697.8

Gene ID:

WBGene00022808

Protein ID:

O44578

Persistent Id:

PTN000044641

Alternate Ids:

ZK697(WormBase_TRS)	HIU hydrolase(Synonym)
ZK697.8(Ensembl_TRS)	CE40007(WormBase_PRO)
FO081798(EMBL)	CCD74369(EMBL-CDS)
114152897(GI)	WBGene00022808(Ensembl)
NP_503496(refSeq)	3.5.2.17(EC)
191414(GeneID)	WBGene00022808(WormBase)
ZK697.8(Ensembl_PRO)	HIUH2_CAEEL(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	URICASE AND TRANSTHYRETIN-RELATED (PTHR10395)
PANTHER Subfamily:	5-HYDROXYISOURATE HYDROLASE (PTHR10395:SF7)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	purine nucleobase metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	hydroxyisourate hydrolase activity, hydrolase activity
GO BP Complete:	purine nucleobase metabolic process
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neutrophil degranulation, Retinoid metabolism and transport, Innate Immune System, Metabolism of vitamins and cofactors, Immune System, Metabolism of fat-soluble vitamins, Sensory Perception, Visual phototransduction, Metabolism, Extracellular matrix organization, Non-integrin membrane-ECM interactions

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12405\|UniProtKB=P02766	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009949\|UniProtKB=Q5U7I5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008865.3\|UniProtKB=G3S3S9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000052277.1\|UniProtKB=A0A1D5QXZ0	Macaca mulatta	O
MOUSE\|MGI=MGI=98865\|UniProtKB=P07309	Mus musculus	O
RAT\|RGD=3916\|UniProtKB=P02767	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010991\|UniProtKB=O46375	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000023686.4\|UniProtKB=A0A5G2QIE9	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00060061967\|UniProtKB=P50390	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015875.4\|UniProtKB=F6UL68	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011314.4\|UniProtKB=M3WEV9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845010593.1\|UniProtKB=A0A8I3NFK0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000010932\|UniProtKB=P49141	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005619.3\|UniProtKB=F7B925	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010004315.1\|UniProtKB=A0A1L1RWR0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017854.4\|UniProtKB=H9GPT6	Anolis carolinensis	O
XENLA\|Gene=ttr.S\|UniProtKB=A0A8J1L2L7	Xenopus laevis	O
XENLA\|Gene=ttr.L\|UniProtKB=A0A8J1KY98	Xenopus laevis	O
XENLA\|Gene=ttr\|UniProtKB=B7ZS96	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-479395\|UniProtKB=A4QNN7	Xenopus tropicalis	O
DANRE\|ZFIN=ZDB-GENE-040927-14\|UniProtKB=B8JLL8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006716.1\|UniProtKB=W5MIA2	lepisosteus oculatus	O
MACMU\|Ensembl=ENSMMUG00000061432.1\|UniProtKB=A0A5F7ZVT8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1916142\|UniProtKB=Q9CRB3	Mus musculus	LDO
RAT\|RGD=1309350\|UniProtKB=D3ZCS9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000053828.1\|UniProtKB=A0A3Q1MFA2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049980.1\|UniProtKB=A0A3Q1LM78	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000048594.1\|UniProtKB=A0A3Q1MEM0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000055124.1\|UniProtKB=A0A3Q1MKT2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000029761.3\|UniProtKB=A0A5G2RCA9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013487.3\|UniProtKB=A0A9L0RS30	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024657.4\|UniProtKB=M3X967	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000895.1\|UniProtKB=A0A8I3MFT6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003287.2\|UniProtKB=F7EG90	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002352.3\|UniProtKB=F6TMP7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008116.1\|UniProtKB=A0A8V0XY10	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000039117.1\|UniProtKB=A0A803U126	Anolis carolinensis	LDO
XENLA\|Gene=urah.S\|UniProtKB=A0A1L8GEP1	Xenopus laevis	O
XENLA\|Gene=urah.L\|UniProtKB=A0A310TNV3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5870986\|UniProtKB=A0A8J0R2W1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029953.1\|UniProtKB=A0A3B3IHM9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-161215-1\|UniProtKB=E7F0I1	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000009326.2\|UniProtKB=H2LZW8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060825-253\|UniProtKB=Q06S87	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001632.1\|UniProtKB=W5M0G9	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118419194\|UniProtKB=A0A9J7LEN8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589020\|UniProtKB=A0A7M7TH82	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00027104\|UniProtKB=A8WXJ6	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0050016\|UniProtKB=A1Z8C9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000415\|UniProtKB=Q7QFD2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002488\|UniProtKB=D6WHM5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_230132\|UniProtKB=E9FRK0	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG35134\|UniProtKB=B3SFS1	Trichoplax adhaerens	LDO
CANAL\|CGD=CAL0000201199\|UniProtKB=Q59Y16	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F22605g\|UniProtKB=Q6C0Q5	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02910\|UniProtKB=Q5B970	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G11340\|UniProtKB=Q4WY06	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01428\|UniProtKB=V5ILW6	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04839\|UniProtKB=A7EHP7	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_05678\|UniProtKB=Q0URD6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC285.04\|UniProtKB=O74492	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04300\|UniProtKB=B6K6G9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNF03210\|UniProtKB=Q5KF36	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10879\|UniProtKB=A0A0D1E4M4	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_18353\|UniProtKB=E3L743	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_11754\|UniProtKB=F4P3H7	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0286691\|UniProtKB=Q54LD6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_46037\|UniProtKB=F0ZD80	Dictyostelium purpureum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_39767\|UniProtKB=B8BWT1	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G634_PHYRM\|UniProtKB=H3G634	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_17g735950v5\|UniProtKB=A8JC88	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00149p00082270\|UniProtKB=W1PNL1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_26G01190\|UniProtKB=A0A0K9PEG9	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g13850\|UniProtKB=A0A804J467	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_036539mg\|UniProtKB=K4ACD2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G350400\|UniProtKB=A0A1Z5S965	Sorghum bicolor	LDO
ORYSJ\|EnsemblGenome=Os03g0390700\|UniProtKB=Q7XXQ9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g60700v3\|UniProtKB=I1H4V4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0386000\|UniProtKB=A0A8I6X2Q8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G104800\|UniProtKB=A0A3B6HS87	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4D02G200200\|UniProtKB=A0A3B6JLA3	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4B02G199200\|UniProtKB=A0A3B6IS20	Triticum aestivum	LDO
NELNU\|Gene=LOC104610376\|UniProtKB=A0A1U8BEV9	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110793295\|UniProtKB=A0A9R0IRG3	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr04g0123661\|UniProtKB=A0A251V2D8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700346860\|UniProtKB=A0A9R1X4N6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009715mg\|UniProtKB=A0A022RSF0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_03136\|UniProtKB=A0A1U8ELB3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400001820\|UniProtKB=M0ZNN6	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g080940.3\|UniProtKB=A0A3Q7F1U7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107812655\|UniProtKB=A0A1S4BWQ6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107773252\|UniProtKB=A0A1S3Y869	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi09g01227\|UniProtKB=D7T3Z8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D01130\|UniProtKB=A0A059CFR8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A02P07860.1\|UniProtKB=A0A078H4E3	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra020380\|UniProtKB=M4DV37	Brassica campestris	LDO
ARATH\|TAIR=locus=2161208\|UniProtKB=Q9LVM5	Arabidopsis thaliana	LDO
THECC\|EnsemblGenome=TCM_011950\|UniProtKB=A0A061G0G3	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g020289mg\|UniProtKB=A0A067H041	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G238300v3\|UniProtKB=A0A2K2BNI6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_08G055700\|UniProtKB=A0A2C9VEY4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0659660\|UniProtKB=B9SKJ6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_03G093200\|UniProtKB=C6TNM5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_16G080700\|UniProtKB=I1MM35	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g010550\|UniProtKB=A0A072TLH0	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_02540\|UniProtKB=A0A2I4GMN6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G127080\|UniProtKB=A0A0A0L3W8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G109200\|UniProtKB=M5XKG8	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_423096\|UniProtKB=D8SKJ9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402204\|UniProtKB=D8QPX2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c4_10360\|UniProtKB=A0A7I4DU75	Physcomitrella patens	LDO
KLENI\|Gene_ORFName=KFL_000570130\|UniProtKB=A0A0U9HRU6	Klebsormidium nitens	LDO
STRCO\|Gene_OrderedLocusName=SCO6210\|UniProtKB=Q9Z592	Streptomyces coelicolor	LDO
BACSU\|EnsemblGenome=BSU_32460\|UniProtKB=O32142	Bacillus subtilis	LDO
DEIRA\|EnsemblGenome=DR_1161\|UniProtKB=Q9RV69	Deinococcus radiodurans	LDO
BRADU\|Gene=Q89Q47_BRADU\|UniProtKB=Q89Q47	Bradyrhizobium diazoefficiens	LDO
XANCP\|EnsemblGenome=XCC0278\|UniProtKB=Q8PDQ7	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA1518\|UniProtKB=Q9I3J5	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM1097\|UniProtKB=Q8ZQ52	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAE76558\|UniProtKB=P76341	Escherichia coli	LDO