PANTHER Gene Information

Gene Symbol(s):

smg-8

Organism:

Caenorhabditis elegans

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Gene Name:

Nonsense-mediated mRNA decay factor SMG8

Gene ID:

WBGene00010551

Protein ID:

O62301

Persistent Id:

PTN000318083

Alternate Ids:

K04B12.3a(Ensembl_TRS)	smg-8(Symbol)
Z83232(EMBL)	CAB05756(EMBL-CDS)
159572284(GI)	WBGene00010551(Ensembl)
NP_497003(refSeq)	SMG8_CAEEL(UniProtKB-ID)
WBGene00010551(WormBase)	175103(GeneID)
K04B12.3a(WormBase_TRS)	CE41824(WormBase_PRO)
Suppressor with morphogenetic effect on genitalia protein 8(Synonym)	K04B12.3a(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	AMPLIFIED IN BREAST CANCER 2-RELATED (PTHR13091)
PANTHER Subfamily:	NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 (PTHR13091:SF0)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
PANTHER GO-slim Cellular Component:
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	molecular_function
GO BP Complete:	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO CC Complete:	cytoplasm, striated muscle dense body

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC), Metabolism of RNA, Nonsense-Mediated Decay (NMD)

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25551\|UniProtKB=Q8ND04	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009465.7\|UniProtKB=H2QDK0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002998.3\|UniProtKB=G3QKH4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000056514.1\|UniProtKB=F7HS41	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1921383\|UniProtKB=Q8VE18	Mus musculus	LDO
RAT\|RGD=1306862\|UniProtKB=D3ZQ80	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003365\|UniProtKB=A1A4J7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000024411.4\|UniProtKB=I3LLC0	Sus scrofa	LDO
PIG\|Ensembl=ENSSSCG00000034353.3\|UniProtKB=A0A287AXJ0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015244.3\|UniProtKB=F7DR34	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013335.6\|UniProtKB=M3WIN9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845024758.1\|UniProtKB=A0A8I3PWU0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014605.5\|UniProtKB=F6ZEN2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008508.5\|UniProtKB=F6XJR3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029929.1\|UniProtKB=A0A8V1AQ98	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013600.4\|UniProtKB=H9GK17	Anolis carolinensis	LDO
XENLA\|Gene=smg8.S\|UniProtKB=A0A1L8H862	Xenopus laevis	O
XENLA\|Gene=smg8.L\|UniProtKB=A0A1L8HG19	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-965595\|UniProtKB=Q0VA04	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014233.2\|UniProtKB=H2MGV8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-091204-279\|UniProtKB=E7FBA3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001234.1\|UniProtKB=W5LZ40	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004205.2\|UniProtKB=F7ALJ6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410328\|UniProtKB=A0A9J7MHL3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100888744\|UniProtKB=A0A7M7NXC7	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00024282\|UniProtKB=A8WP66	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0032296\|UniProtKB=Q9VKQ6	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010179\|UniProtKB=A0A1S4H457	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013382\|UniProtKB=D6WLV3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_222870\|UniProtKB=E9G817	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG190258\|UniProtKB=T1FRT7	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG57395\|UniProtKB=B3RZB8	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_37453\|UniProtKB=A9V1U8	Monosiga brevicollis	LDO
DICDI\|dictyBase=DDB_G0272470\|UniProtKB=Q75JP6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_53257\|UniProtKB=F0ZBZ9	Dictyostelium purpureum	LDO
PHYRM\|Gene=H3GT97_PHYRM\|UniProtKB=H3GT97	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g347700v5\|UniProtKB=A0A2K3DL25	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00102p00057640\|UniProtKB=W1NXY8	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_1G00550\|UniProtKB=A0A0K9PM91	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g12010\|UniProtKB=A0A804INT2	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016139mg\|UniProtKB=K3YPE7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G351600\|UniProtKB=C5XW19	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb190880\|UniProtKB=A0A1D6QAI1	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0823800\|UniProtKB=Q6K9X0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g55905v3\|UniProtKB=I1IE53	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0631580\|UniProtKB=A0A8I7BCT3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G388100\|UniProtKB=A0A3B6QPF5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G449100\|UniProtKB=A0A3B6PU77	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G404800\|UniProtKB=A0A3B6NX83	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_030063\|UniProtKB=A0A1U7YSJ2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110787963\|UniProtKB=A0A9R0JVQ2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0509841\|UniProtKB=A0A251TDP1	Helianthus annuus	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a023242mg\|UniProtKB=A0A022RDS4	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_18109\|UniProtKB=A0A2G2ZDG3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400007133\|UniProtKB=M1AAI1	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc06g074810.3\|UniProtKB=A0A3Q7H3H2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107775706\|UniProtKB=A0A1S3YG89	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107815081\|UniProtKB=A0A1S4C4U9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi06g01348\|UniProtKB=F6GW82	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J00389\|UniProtKB=A0A059AA40	Eucalyptus grandis	LDO
THECC\|EnsemblGenome=TCM_041589\|UniProtKB=A0A061GW57	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0009661mg\|UniProtKB=A0A067EYS2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_009G005300v3\|UniProtKB=A0A2K1Z0L1	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_04G012900\|UniProtKB=A0A2C9VYN9	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0474930\|UniProtKB=B9SCK8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_12G178700\|UniProtKB=K7LVL9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G322000\|UniProtKB=K7M344	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g084285\|UniProtKB=A0A072VBC2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_14920\|UniProtKB=A0A2I4EHU9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G148270\|UniProtKB=A0A0A0KGK1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G112700\|UniProtKB=A0A251NNQ4	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c19_6480\|UniProtKB=A0A2K1IXF9	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0011s0199\|UniProtKB=A0A2R6XK90	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003220040\|UniProtKB=A0A1Y1IAG0	Klebsormidium nitens	LDO