PANTHER Gene Information   
Gene Symbol(s): Fgd4
Organism: Rattus norvegicus
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Gene Name: FYVE, RhoGEF and PH domain-containing protein 4
Gene ID: 708357
Protein ID: O88387
Persistent Id: PTN000292853
Alternate Ids:
708357(RGD) 246174(GeneID)
Fgd4(Symbol) Actin filament-binding protein frabin(Synonym)
AF038388(EMBL) ENSRNOT00000084177(Ensembl_TRS)
ENSRNOG00000059491(Ensembl) AAC27698(EMBL-CDS)
NM_139263(refSeq) 21245110(GI)
ENSRNOP00000074767(Ensembl_PRO) FGD4_RAT(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: FACIOGENITAL DYSPLASIA PROTEIN (PTHR12673)
PANTHER Subfamily: FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 4 (PTHR12673:SF98)  
PANTHER GO-slim Molecular Function: guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process: filopodium assembly
cytoskeleton organization
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class: guanyl-nucleotide exchange factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: actin filament binding, actin binding, metal ion binding, guanyl-nucleotide exchange factor activity
GO BP Complete: regulation of cell shape, positive regulation of JUN kinase activity, cytoskeleton organization, positive regulation of JNK cascade, lamellipodium assembly, microspike assembly, filopodium assembly
GO CC Complete: cytoskeleton, cytoplasm, filopodium, lamellipodium
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Death Receptor Signaling, RHO GTPase cycle, Signaling by GPCR, GPCR downstream signalling, Signaling by Rho GTPases, Cell death signalling via NRAGE, NRIF and NADE, Signal Transduction, CDC42 GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, NRAGE signals death through JNK, p75 NTR receptor-mediated signalling, G alpha (12/13) signalling events

Orthologs