PANTHER Gene Information

Gene Symbol(s):

Pdp2

Organism:

Rattus norvegicus

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Gene Name:

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

Gene ID:

628812

Protein ID:

O88484

Persistent Id:

PTN000353353

Alternate Ids:

3298609(GI)	PDP2_RAT(UniProtKB-ID)
628812(RGD)	246311(GeneID)
AAH72485(EMBL-CDS)	PDPC 2(Synonym)
Pdp2(Symbol)	NM_145091(refSeq)
AF062741(EMBL)	3.1.3.43(EC)
Q6IN27(AltAccession)
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PANTHER Classification

PANTHER Family:	PROTEIN PHOSPHATASE 2C (PTHR13832)
PANTHER Subfamily:	[PYRUVATE DEHYDROGENASE [ACETYL-TRANSFERRING]]-PHOSPHATASE 2, MITOCHONDRIAL (PTHR13832:SF343)
PANTHER GO-slim Molecular Function:	protein serine/threonine phosphatase activity
PANTHER GO-slim Biological Process:	protein dephosphorylation
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	protein phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein serine/threonine phosphatase activity, metal ion binding, [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity
GO BP Complete:	peptidyl-threonine dephosphorylation, T-helper cell differentiation, signal transduction, response to starvation
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, The citric acid (TCA) cycle and respiratory electron transport, Regulation of pyruvate dehydrogenase (PDH) complex, Pyruvate metabolism, Pyruvate metabolism and Citric Acid (TCA) cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=30263\|UniProtKB=Q9P2J9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000047529.1\|UniProtKB=H2QBA2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012328.3\|UniProtKB=G3S0L5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016726.3\|UniProtKB=F6VCV0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1918878\|UniProtKB=Q504M2	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000046708.2\|UniProtKB=G3N1T9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005007054.1\|UniProtKB=A0A287B2X3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006359.3\|UniProtKB=F7A4F3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006269.5\|UniProtKB=M3W5L0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011036.1\|UniProtKB=A0A8I3NTB1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006788.3\|UniProtKB=A0A5F8HLR0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000015274.2\|UniProtKB=F6RSX9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009761.1\|UniProtKB=F1NW03	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002437.3\|UniProtKB=H9G683	Anolis carolinensis	LDO
XENLA\|Gene=pdp2.L\|UniProtKB=A0A1L8GL17	Xenopus laevis	O
XENLA\|Gene=LOC121393084\|UniProtKB=A0A8J1KLM7	Xenopus laevis	LDO
XENTR\|Gene=pdp2\|UniProtKB=A0A8J0QXV9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009798.2\|UniProtKB=A0A3B3HCF3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-000921-2\|UniProtKB=Q32LW9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017591.1\|UniProtKB=W5NM37	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118408871\|UniProtKB=A0A9J7KLR7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584018\|UniProtKB=A0A7M7N4Z9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022832\|UniProtKB=Q9N4M0	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG12191\|UniProtKB=A8XF12	Caenorhabditis briggsae	LDO
CAEBR\|WormBase=WBGene00042165\|UniProtKB=A8WJL9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090956\|UniProtKB=A0A2A6BSM5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0029958\|UniProtKB=Q9W3Q1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008349\|UniProtKB=A0A1S4GY06	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC032568\|UniProtKB=A0A139WKL9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_202806\|UniProtKB=E9HFI0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW014874\|UniProtKB=B7QLI2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG98081\|UniProtKB=T1G9K4	helobdella robusta	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g100712\|UniProtKB=A7S1G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g228005\|UniProtKB=A7RHC1	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32270\|UniProtKB=A9UYG5	Monosiga brevicollis	LDO
YEAST\|SGD=S000005616\|UniProtKB=Q12511	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ACL083C\|UniProtKB=Q75CK2	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000200868\|UniProtKB=Q5A388	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D07040g\|UniProtKB=Q6C9Z9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05722\|UniProtKB=Q5B158	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G06860\|UniProtKB=Q4WJ85	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01767\|UniProtKB=F5HHC3	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_10886\|UniProtKB=A7EZW9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11466\|UniProtKB=Q0U9U8	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04916\|UniProtKB=Q0UTJ8	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC10F6.17c\|UniProtKB=O14189	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03310\|UniProtKB=B6K3W6	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA04120\|UniProtKB=Q5KP56	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01286\|UniProtKB=A0A0D1E758	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_10677\|UniProtKB=E3KJ24	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34770\|UniProtKB=F4NZX5	Batrachochytrium dendrobatidis	LDO
PLAF7\|EnsemblGenome=PF3D7_1135100\|UniProtKB=Q8II13	Plasmodium falciparum	LDO
CHLAA\|EnsemblGenome=Caur_2654\|UniProtKB=A9WJF6	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_3816\|UniProtKB=A9WCN2	Chloroflexus aurantiacus	O
MYCTU\|Gene_OrderedLocusName=Rv0018c\|UniProtKB=P9WHW5	Mycobacterium tuberculosis	O
DEIRA\|EnsemblGenome=DR_2513\|UniProtKB=Q9RRH8	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NP99_GLOVI\|UniProtKB=Q7NP99	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NKS2_GLOVI\|UniProtKB=Q7NKS2	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NGY0_GLOVI\|UniProtKB=Q7NGY0	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB8362\|UniProtKB=Q7UFS9	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_933\|UniProtKB=O67075	Aquifex aeolicus	O
BRADU\|Gene=Q89P80_BRADU\|UniProtKB=Q89P80	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC0989\|UniProtKB=Q8PBX6	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA0075\|UniProtKB=Q9I757	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA1670\|UniProtKB=Q9I355	Pseudomonas aeruginosa	O
CHLAA\|EnsemblGenome=Caur_1132\|UniProtKB=A9WJ85	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2667\|UniProtKB=Q9L254	Streptomyces coelicolor	O
MYCGE\|EnsemblGenome=MG_108\|UniProtKB=P47354	mycoplasma genitalium	O
CLOBH\|Gene_OrderedLocusName=CBO2505\|UniProtKB=A5I4T3	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1578\|UniProtKB=Q8DNR9	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01186\|UniProtKB=Q2FZ65	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99899\|UniProtKB=Q8Y678	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_15760\|UniProtKB=O34779	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3861\|UniProtKB=Q819U4	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_A0334\|UniProtKB=Q9RYH8	Deinococcus radiodurans	O
LEPIN\|EnsemblGenome=LA_1428\|UniProtKB=Q8F681	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_2772\|UniProtKB=Q8A432	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_259\|UniProtKB=O84261	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB3245\|UniProtKB=Q7UUK3	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_575\|UniProtKB=O66843	Aquifex aeolicus	O