PANTHER Gene Information   
Gene Symbol(s): APE1
Organism: Plasmodium falciparum
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Gene Name: DNA-(apurinic or apyrimidinic site) endonuclease
Gene ID: PF3D7_0305600
Protein ID: O97240
Persistent Id: PTN001100823
Alternate Ids:
3.1.11.2 {ECO:0000269|PubMed:33743509}(EC) PfAPE1 {ECO:0000303|PubMed:33743509}(Synonym)
CAB39006(Ensembl_PRO) 15375379(GI)
XM_001351096(refSeq) 814374(GeneID)
PF3D7_0305600(Ensembl) APEX_PLAF7(UniProtKB-ID)
AL844502(EMBL) CAB39006(EMBL-CDS)
APE1{ECO:0000303|PubMed:33743509}(Symbol) CAB39006(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: AP ENDONUCLEASE (PTHR22748)
PANTHER Subfamily: DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE (PTHR22748:SF6)  
PANTHER GO-slim Molecular Function: 3'-5'-DNA exonuclease activity
phosphoric diester hydrolase activity
PANTHER GO-slim Biological Process: base-excision repair
PANTHER GO-slim Cellular Component:
PANTHER protein class:
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: 3'-5' exonuclease activity, phosphatase activity, DNA-(apurinic or apyrimidinic site) endonuclease activity, RNA nuclease activity, double-stranded DNA 3'-5' DNA exonuclease activity, phosphoric diester hydrolase activity
GO BP Complete: symbiont entry into host, base-excision repair
GO CC Complete: nucleus, mitochondrion
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Resolution of AP sites via the multiple-nucleotide patch replacement pathway, Base Excision Repair, DNA Repair, PCNA-Dependent Long Patch Base Excision Repair, Displacement of DNA glycosylase by APEX1, Resolution of Abasic Sites (AP sites)

Orthologs