The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

AVP

Organism:

Bos taurus

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Tree

Gene Name:

Vasopressin-neurophysin 2-copeptin

Gene ID:

AVP

Protein ID:

P01180

Persistent Id:

PTN007526208

Alternate Ids:

590(GI)	NEU2_BOVIN(UniProtKB-ID)
CAA23447(EMBL-CDS)	NP_789824(refSeq)
Q3SZF1(AltAccession)	V00113(EMBL)
AVP(Symbol)	Neurophysin-II(Synonym)
280728(GeneID)
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PANTHER Classification

PANTHER Family:	NEUROPHYSIN (PTHR11681)
PANTHER Subfamily:	VASOPRESSIN-NEUROPHYSIN 2-COPEPTIN (PTHR11681:SF9)
PANTHER GO-slim Molecular Function:	neuropeptide hormone activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	secretory granule extracellular space
PANTHER protein class:	neuropeptide

Pathway Categories:

Vasopressin synthesis

Glycopeptide

Opioid prodynorphin pathway

provasopressin

Opioid prodynorphin pathway

prepropressophysin

Vasopressin synthesis

Neurophysin

Vasopressin synthesis

Signal Peptide

Opioid prodynorphin pathway

vasopressin

Vasopressin synthesis

Pro2-Vasopressin

Vasopressin synthesis

Pro-Neurophysin

Vasopressin synthesis

Pro-Vasopressin

Opioid prodynorphin pathway

prepropressophysin

Vasopressin synthesis

Vasopressin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	neurohypophyseal hormone activity, neuropeptide hormone activity, V1A vasopressin receptor binding
GO BP Complete:	signal transduction, vasoconstriction
GO CC Complete:	extracellular space, secretory granule, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

-

Orthologs

ID	Organism	Type
HUMAN\|HGNC=894\|UniProtKB=P01185	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013190.6\|UniProtKB=H2QJV2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000027655.2\|UniProtKB=G3RSG3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000051923.1\|UniProtKB=A0A5F8A1E9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=88121\|UniProtKB=P35455	Mus musculus	LDO
RAT\|RGD=2184\|UniProtKB=P01186	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000007163.5\|UniProtKB=A0A5G2RBT2	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00025044667\|UniProtKB=P01183	Sus scrofa	LDO
HORSE\|Gene=AVP\|UniProtKB=P01182	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000046132.2\|UniProtKB=A0A2I2U5X4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845015347.1\|UniProtKB=A0A8I3NZX3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005416.3\|UniProtKB=F7FVE9	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000005441.3\|UniProtKB=F7D0Q1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013035.3\|UniProtKB=F7BNK7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010016585.1\|UniProtKB=E1C7F2	Gallus gallus	LDO
XENLA\|Gene=oxt.S\|UniProtKB=A0A1L8HKH4	Xenopus laevis	O
XENLA\|Gene=oxt.L\|UniProtKB=A0A1L8HSF0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-478274\|UniProtKB=F6X0Y1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000003809.2\|UniProtKB=H2LFK3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022162.1\|UniProtKB=A0A3B3IJH1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030407-2\|UniProtKB=Q8AV79	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030407-1\|UniProtKB=Q8UUT8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001161.1\|UniProtKB=W5LYV0	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001173.1\|UniProtKB=W5LYW1	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_84802\|UniProtKB=C3Y3Y0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC752998\|UniProtKB=A0A7M7NTV5	Strongylocentrotus purpuratus	O
TRICA\|EnsemblGenome=TC006626\|UniProtKB=A3RE83	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_59567\|UniProtKB=E9H8T6	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG77987\|UniProtKB=T1G361	helobdella robusta	O