PANTHER Gene Information

Gene Symbol(s):

HBB

Organism:

Bos taurus

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Gene Name:

Hemoglobin subunit beta

Gene ID:

ENSBTAG00000037644

Protein ID:

P02070

Persistent Id:

PTN000154368

Alternate Ids:

Hemoglobin beta chain(Synonym)	576145(GI)
ENSBTAT00000057323(Ensembl_TRS)	HBB(Symbol)
M63453(EMBL)	AAA30408(EMBL-CDS)
280813(GeneID)	ENSBTAP00000050256(Ensembl_PRO)
NM_173917(refSeq)	HBB_BOVIN(UniProtKB-ID)
ENSBTAG00000037644(Ensembl)
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PANTHER Classification

PANTHER Family:	HEMOGLOBIN FAMILY MEMBER (PTHR11442)
PANTHER Subfamily:	HEMOGLOBIN SUBUNIT BETA (PTHR11442:SF42)
PANTHER GO-slim Molecular Function:	organic acid binding antioxidant activity oxidoreductase activity, acting on peroxide as acceptor protein binding heme binding
PANTHER GO-slim Biological Process:	cellular catabolic process
PANTHER GO-slim Cellular Component:	cytosol protein-containing complex extracellular space
PANTHER protein class:	globin

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	peroxidase activity, oxygen binding, metal ion binding, hemoglobin alpha binding, oxygen carrier activity, heme binding, haptoglobin binding
GO BP Complete:	oxygen transport, cellular oxidant detoxification, hydrogen peroxide catabolic process
GO CC Complete:	hemoglobin complex, haptoglobin-hemoglobin complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cellular responses to stimuli, Erythrocytes take up oxygen and release carbon dioxide, O2/CO2 exchange in erythrocytes, Cellular response to chemical stress, Cytoprotection by HMOX1, Neutrophil degranulation, Scavenging of heme from plasma, Immune System, Transport of small molecules, Innate Immune System, Cellular responses to stress, Heme signaling, Erythrocytes take up carbon dioxide and release oxygen, Vesicle-mediated transport, Binding and Uptake of Ligands by Scavenger Receptors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4829\|UniProtKB=P02042	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000028344.2\|UniProtKB=G3RYX7	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000021936.2\|UniProtKB=G3SIN5	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000003238\|UniProtKB=P61772	Pan troglodytes	O
GORGO\|Gene=HBD\|UniProtKB=P61773	Gorilla gorilla gorilla	O
HUMAN\|HGNC=4827\|UniProtKB=P68871	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000040047\|UniProtKB=P68873	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000043805\|UniProtKB=P02024	Gorilla gorilla gorilla	LDO
MACMU\|Gene=HBB\|UniProtKB=P02026	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96025\|UniProtKB=B2RVB7	Mus musculus	O
MOUSE\|MGI=MGI=96022\|UniProtKB=P02089	Mus musculus	O
MOUSE\|MGI=MGI=96021\|UniProtKB=P02088	Mus musculus	O
MOUSE\|MGI=MGI=5474850\|UniProtKB=A8DUK4	Mus musculus	LDO
RAT\|Ensembl=ENSRNOG00000047098\|UniProtKB=P11517	Rattus norvegicus	O
RAT\|RGD=2783\|UniProtKB=P02091	Rattus norvegicus	LDO
PIG\|Gene=HBB\|UniProtKB=P02067	Sus scrofa	LDO
PIG\|Ensembl=ENSSSCG00000014727.5\|UniProtKB=F1RII5	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000014725.6\|UniProtKB=A0A5G2QRW3	Sus scrofa	LDO
HORSE\|Gene=HBB\|UniProtKB=P02062	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000010020.4\|UniProtKB=F6RDD3	Equus caballus	LDO
FELCA\|Gene=HBB\|UniProtKB=P07412	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020234.1\|UniProtKB=A0A1K0GGH0	Canis lupus familiaris	LDO
CANLF\|Gene=HBB\|UniProtKB=P60524	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011306.3\|UniProtKB=F6WYU4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011325.4\|UniProtKB=F6WII6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049640.1\|UniProtKB=A0A6I8PBU0	Ornithorhynchus anatinus	O
ORNAN\|Gene=HBB\|UniProtKB=P02111	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000043521.1\|UniProtKB=A0A6I8P156	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00015003366\|UniProtKB=P02128	Gallus gallus	O
CHICK\|Gene=HBRH_CHICK\|UniProtKB=P02127	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010003363.1\|UniProtKB=A0A8V0XG92	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010003868\|UniProtKB=P02112	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012173.3\|UniProtKB=H9GIN1	Anolis carolinensis	O
XENLA\|Gene=HBBL_XENLA\|UniProtKB=P02137	Xenopus laevis	O
XENLA\|Gene=LOC108701506\|UniProtKB=A0A1L8EXA4	Xenopus laevis	O
XENLA\|Gene=hbe1.L\|UniProtKB=Q66KY4	Xenopus laevis	O
XENLA\|Gene=LOC108702417\|UniProtKB=A0A1L8EQ81	Xenopus laevis	O
XENLA\|Gene=LOC108702418\|UniProtKB=A0A1L8EQ40	Xenopus laevis	O
XENTR\|Gene=LOC101735171\|UniProtKB=A0A8J0R500	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5745824\|UniProtKB=B0BMS6	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5722135\|UniProtKB=P08423	Xenopus tropicalis	O
XENLA\|Gene=hbg2.S\|UniProtKB=Q6DKM5	Xenopus laevis	O
XENLA\|Gene=hbb1\|UniProtKB=P02132	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5912896\|UniProtKB=P07429	Xenopus tropicalis	O
XENLA\|Gene=hbb2\|UniProtKB=P02133	Xenopus laevis	O
XENLA\|Gene=LOC108703093\|UniProtKB=A0A1L8EQ32	Xenopus laevis	O
XENLA\|Gene=LOC108703094\|UniProtKB=A0A1L8EQ13	Xenopus laevis	O
XENLA\|Gene=XB5745823.L\|UniProtKB=A2VDC3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5808005\|UniProtKB=Q6DJ70	Xenopus tropicalis	O
XENTR\|Gene=LOC100216007\|UniProtKB=B0JZZ3	Xenopus tropicalis	O
XENTR\|Ensembl=ENSXETG00000045178\|UniProtKB=A0A5G3HUQ0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005283.2\|UniProtKB=H2LKV1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040801-164\|UniProtKB=Q6ZM12	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000021881.1\|UniProtKB=A0A3B3HGW9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-990415-18\|UniProtKB=Q90486	Danio rerio	O
DANRE\|Gene_ORFName=si=dz118j2.1\|UniProtKB=Q90485	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000030133.1\|UniProtKB=Q8AYQ5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025745.1\|UniProtKB=Q8AYQ6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000026120.1\|UniProtKB=A0A3B3HT58	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025271.1\|UniProtKB=Q8JIN1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040702-1\|UniProtKB=Q7T1B0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-980526-287\|UniProtKB=Q5BLF6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-090501-3\|UniProtKB=O93548	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007843.1\|UniProtKB=W5MMA8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007787.1\|UniProtKB=W5MM40	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007827.1\|UniProtKB=W5MM94	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007852.1\|UniProtKB=W5MMC3	lepisosteus oculatus	O