PANTHER Gene Information

Gene Symbol(s):

Mt2

Organism:

Rattus norvegicus

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Gene Name:

Metallothionein-2

Gene ID:

ENSRNOG00000043098

Protein ID:

P04355

Persistent Id:

PTN001151665

Alternate Ids:

127401(GI)	MT2_RAT(UniProtKB-ID)
MT-II(Synonym)	NM_001137564(refSeq)
ENSRNOG00000043098(Ensembl)	689415(GeneID)
AAA41640(EMBL-CDS)	M11794(EMBL)
Mt2(Symbol)	ENSRNOT00000067391(Ensembl_TRS)
ENSRNOP00000062585(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	METALLOTHIONEIN (PTHR23299)
PANTHER Subfamily:	METALLOTHIONEIN-1G (PTHR23299:SF22)
PANTHER GO-slim Molecular Function:	metal ion binding
PANTHER GO-slim Biological Process:	detoxification response to stress inorganic ion homeostasis intracellular monoatomic cation homeostasis cellular response to chemical stimulus
PANTHER GO-slim Cellular Component:	cytoplasm nucleus
PANTHER protein class:	defense/immunity protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding
GO BP Complete:	detoxification of copper ion, cellular response to zinc ion, cellular response to cadmium ion, intracellular zinc ion homeostasis, cellular response to copper ion
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cellular responses to stimuli, Metallothioneins bind metals, Response to metal ions

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7393\|UniProtKB=P04731	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000031204.3\|UniProtKB=H2QB56	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000023548.2\|UniProtKB=G3RN95	Gorilla gorilla gorilla	O
HUMAN\|HGNC=31864\|UniProtKB=P0DM35	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043308.1\|UniProtKB=A0A2I3T4H4	Pan troglodytes	O
HUMAN\|HGNC=7400\|UniProtKB=P80294	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000042180.2\|UniProtKB=H2RHP7	Pan troglodytes	O
HUMAN\|HGNC=7399\|UniProtKB=P13640	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008140.5\|UniProtKB=H2QB57	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013582.3\|UniProtKB=G3RQM3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000054142.1\|UniProtKB=A0A5F8AM23	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000061767.1\|UniProtKB=A0A5F7Z9H2	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000059572.1\|UniProtKB=A0A5F7ZAH7	Macaca mulatta	LDO
PANTR\|Ensembl=ENSPTRG00000031203.4\|UniProtKB=H2RH18	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009843.3\|UniProtKB=G3R2Z7	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000050915.1\|UniProtKB=A0A2I3SUU4	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000059112.1\|UniProtKB=A0A5F8A269	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000060514.1\|UniProtKB=A0A5F8A118	Macaca mulatta	O
PANTR\|Ensembl=ENSPTRG00000049747.1\|UniProtKB=A0A2I3RA88	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000040689.1\|UniProtKB=A0A2I2YTY6	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000044894.1\|UniProtKB=H2R9Y4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000044456.1\|UniProtKB=A0A2I3RJA2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009847.3\|UniProtKB=G3R2Y8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000029122.3\|UniProtKB=A0A5F7ZHG2	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054896.1\|UniProtKB=A0A5F7ZQA4	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054300.1\|UniProtKB=A0A5F8AM57	Macaca mulatta	O
HUMAN\|HGNC=7406\|UniProtKB=P02795	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016106.4\|UniProtKB=H2QPK0	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000049822.1\|UniProtKB=G7NPC6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97172\|UniProtKB=P02798	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000054551.1\|UniProtKB=A0A3Q1MSQ3	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054808.1\|UniProtKB=A0A3Q1M6Y6	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000001595.5\|UniProtKB=A0A3Q1M6T1	Bos taurus	O
BOVIN\|Gene=MT1\|UniProtKB=P58280	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000038706.2\|UniProtKB=A0A3Q1M9T6	Bos taurus	O
BOVIN\|Gene=MT1A\|UniProtKB=P67983	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005042445.1\|UniProtKB=A0A4X1SEK1	Sus scrofa	O
PIG\|Gene=MT1D\|UniProtKB=P79377	Sus scrofa	O
PIG\|Gene=MT1F\|UniProtKB=P79378	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00015010287\|UniProtKB=P79376	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000051968.1\|UniProtKB=A0A287AI89	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000061081\|UniProtKB=P49068	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000059404.1\|UniProtKB=A0A5S8L8D1	Sus scrofa	O
PIG\|Gene=MT1E\|UniProtKB=P79431	Sus scrofa	LDO
HORSE\|Gene=MT1A_HORSE\|UniProtKB=P02800	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000034550.3\|UniProtKB=A0A3Q2HP82	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000015275.4\|UniProtKB=A0A9L0RDD4	Equus caballus	LDO
BOVIN\|Ensembl=ENSBTAG00000054346.1\|UniProtKB=A0A3Q1LY42	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000023659\|UniProtKB=P68301	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000029533.1\|UniProtKB=A0A3Q2GY91	Equus caballus	O
HORSE\|Gene=MT1B_HORSE\|UniProtKB=P02801	Equus caballus	O
BOVIN\|Gene=MT2H_BOVIN\|UniProtKB=P55943	Bos taurus	LDO
BOVIN\|Gene=MT1H_BOVIN\|UniProtKB=P55942	Bos taurus	O
PIG\|Gene=MT2B\|UniProtKB=P79380	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000030300\|UniProtKB=P79379	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000036135.3\|UniProtKB=A0A2I2URE5	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000039827.3\|UniProtKB=A0A2I2UEN6	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000045131.2\|UniProtKB=A0A5F5XDZ2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013719.1\|UniProtKB=A0A8I3NL40	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845027184.1\|UniProtKB=A0A8I3S674	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000000564.2\|UniProtKB=F7G3K7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023744\|UniProtKB=P68497	Gallus gallus	O
ORYLA\|Ensembl=ENSORLG00000015580\|UniProtKB=Q6S4N8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-4174\|UniProtKB=P52722	Danio rerio	O