PANTHER Gene Information   
Gene Symbol(s): Wnt1
Organism: Mus musculus
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: Proto-oncogene Wnt-1
Gene ID: MGI:98953
Protein ID: P04426
Persistent Id: PTN000246673
Alternate Ids:
ENSMUSG00000022997(Ensembl) 33469103(GI)
M11943(EMBL) AAA39322(EMBL-CDS)
Wnt1(Symbol) ENSMUST00000023734(Ensembl_TRS)
ENSMUSP00000023734(Ensembl_PRO) WNT1(Synonym)
MGI:98953(MGI) 22408(GeneID)
NP_067254(refSeq) WNT1_MOUSE(UniProtKB-ID)
Show All

PANTHER Classification
PANTHER Family: WNT RELATED (PTHR12027)
PANTHER Subfamily: PROTO-ONCOGENE WNT-1 (PTHR12027:SF91)  
PANTHER GO-slim Molecular Function: cytokine activity
G protein-coupled receptor binding
PANTHER GO-slim Biological Process: cell fate commitment
canonical Wnt signaling pathway
neuron differentiation
PANTHER GO-slim Cellular Component: extracellular space
PANTHER protein class: intercellular signal molecule
Pathway Categories: Alzheimer disease-presenilin pathway
   Wingless-type MMTV integration site family member
Angiogenesis
   Wingless-type MMTV integration site family member
Cadherin signaling pathway
   Wingless-type MMTV integration site family member
Wnt signaling pathway
   Wingless-type MMTV integration site family member

GO MF Complete: frizzled binding, protein domain specific binding, protein binding, receptor ligand activity, cytokine activity, signaling receptor binding
GO BP Complete: positive regulation of hematopoietic stem cell proliferation, negative regulation of cell-cell adhesion, forebrain anterior/posterior pattern specification, signal transduction in response to DNA damage, neurogenesis, embryonic axis specification, fat cell differentiation, central nervous system morphogenesis, positive regulation of DNA-binding transcription factor activity, midbrain-hindbrain boundary maturation during brain development, midbrain development, negative regulation of cell-substrate adhesion, positive regulation of DNA-templated transcription, hepatocyte differentiation, BMP signaling pathway, embryonic brain development, Wnt signaling pathway, positive regulation of lamellipodium assembly, negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway, cerebellum development, neuron differentiation, cell-cell signaling, cerebellum formation, midbrain dopaminergic neuron differentiation, metencephalon development, animal organ morphogenesis, inner ear morphogenesis, myotube differentiation, animal organ regeneration, cell population proliferation, multicellular organism development, positive regulation of cell population proliferation, diencephalon development, positive regulation of transcription by RNA polymerase II, positive regulation of Notch signaling pathway, positive regulation of insulin-like growth factor receptor signaling pathway, bone development, negative regulation of cell differentiation, neuron fate determination, positive regulation of fibroblast proliferation, neuron fate commitment, canonical Wnt signaling pathway, cell proliferation in midbrain, negative regulation of ubiquitin-dependent protein catabolic process, negative regulation of cellular senescence, positive regulation of dermatome development, signal transduction, spinal cord association neuron differentiation, T cell differentiation in thymus, myoblast fusion, negative regulation of fat cell differentiation, regulation of DNA-templated transcription, midbrain-hindbrain boundary development, negative regulation of BMP signaling pathway, dopaminergic neuron differentiation, branching involved in ureteric bud morphogenesis, negative regulation of apoptotic process, positive regulation of protein phosphorylation, cell fate commitment, hematopoietic stem cell proliferation, Spemann organizer formation, negative regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: endoplasmic reticulum lumen, Wnt signalosome, extracellular space, cytoplasm, extracellular region, cell surface
Reactome Pathways: Signaling by WNT, Disassembly of the destruction complex and recruitment of AXIN to the membrane, Signal Transduction, Beta-catenin independent WNT signaling, WNT ligand biogenesis and trafficking, PCP/CE pathway, TCF dependent signaling in response to WNT