Gene Symbol(s):
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Fga
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Organism: |
Rattus norvegicus |
View Gene in Tree |
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Gene Name: |
Fibrinogen alpha chain
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Gene ID: |
2603
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Protein ID: |
P06399
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Persistent Id: |
PTN000441584 |
Alternate Ids: |
Fga(Symbol) |
FIBA(Synonym) |
M35601(EMBL) |
204140(GI) |
FIBA_RAT(UniProtKB-ID) |
AAA41158(EMBL-CDS) |
2603(RGD) |
Show All
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GO MF Complete: |
metal ion binding, cell adhesion molecule binding, structural molecule activity, signaling receptor binding, protein-macromolecule adaptor activity
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GO BP Complete: |
response to X-ray, positive regulation of vasoconstriction, positive regulation of peptide hormone secretion, response to cycloheximide, blood coagulation, fibrinolysis, response to toxic substance, positive regulation of exocytosis, response to thyroid hormone, liver regeneration, response to insulin, induction of bacterial agglutination, cellular response to interleukin-6, cellular response to granulocyte colony-stimulating factor, plasminogen activation, positive regulation of smooth muscle cell migration, positive regulation of protein secretion, negative regulation of endothelial cell apoptotic process, platelet activation, platelet aggregation, cell-matrix adhesion, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, response to genistein, protein-containing complex assembly, adaptive immune response, response to growth hormone, acute-phase response, envenomation resulting in modulation of blood coagulation in another organism, protein polymerization, blood coagulation, fibrin clot formation, blood coagulation, common pathway, innate immune response, response to calcium ion, positive regulation of ERK1 and ERK2 cascade, response to estradiol, positive regulation of heterotypic cell-cell adhesion, cellular response to organic cyclic compound
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GO CC Complete: |
extracellular space, platelet alpha granule, cell cortex, blood microparticle, external side of plasma membrane, endoplasmic reticulum, synapse, fibrinogen complex, cell surface
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Reactome Pathways: |
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), Integrin cell surface interactions, MAPK family signaling cascades, Hemostasis, Extracellular matrix organization, p130Cas linkage to MAPK signaling for integrins, MAP2K and MAPK activation, Platelet activation, signaling and aggregation, Innate Immune System, Common Pathway of Fibrin Clot Formation, Formation of Fibrin Clot (Clotting Cascade), MAPK1/MAPK3 signaling, Platelet degranulation , Response to elevated platelet cytosolic Ca2+, Signal Transduction, RAF/MAP kinase cascade, Metabolism of proteins, Post-translational protein modification, Platelet Aggregation (Plug Formation), Regulation of TLR by endogenous ligand, Post-translational protein phosphorylation, Immune System, GRB2:SOS provides linkage to MAPK signaling for Integrins , Integrin signaling, Toll-like Receptor Cascades
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