PANTHER Gene Information

Gene Symbol(s):

PIF1

Organism:

Saccharomyces cerevisiae

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Gene Name:

ATP-dependent DNA helicase PIF1

Gene ID:

S000004526

Protein ID:

P07271

Persistent Id:

PTN000588800

Alternate Ids:

PIF1{ECO:0000255\|HAMAP-Rule:MF_03176}(Symbol)	BK006946(EMBL)
854941(GeneID)	PIF1(Synonym)
558414(GI)	3.6.4.12 {ECO:0000255\|HAMAP-Rule:MF_03176}(EC)
PIF1_YEAST(UniProtKB-ID)	S000004526(SGD)
D6VZB2(AltAccession)	CAA86714(EMBL-CDS)
YML061C(Ensembl)	YEAST:G3O-32656-MON(BioCyc)
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PANTHER Classification

PANTHER Family:	DNA HELICASE-RELATED (PTHR23274)
PANTHER Subfamily:	ATP-DEPENDENT DNA HELICASE PIF1 (PTHR23274:SF54)
PANTHER GO-slim Molecular Function:	single-stranded DNA binding
PANTHER GO-slim Biological Process:	telomere maintenance DNA geometric change replication fork processing mitochondrial genome maintenance
PANTHER GO-slim Cellular Component:	nuclear replication fork mitochondrion
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, double-stranded DNA helicase activity, helicase activity, four-way junction helicase activity, forked DNA-dependent helicase activity, cohesin loader activity, single-stranded DNA binding, 5'-3' DNA helicase activity, DNA binding, ATP binding, DNA helicase activity, DNA clamp loader activity, ATP-dependent H2AZ histone chaperone activity, G-quadruplex DNA binding, telomeric DNA binding, ATP-dependent H3-H4 histone complex chaperone activity, single-stranded 3'-5' DNA helicase activity, centromeric DNA binding, telomerase inhibitor activity, chromatin extrusion motor activity, hydrolase activity
GO BP Complete:	DNA repair, double-strand break repair via break-induced replication, G-quadruplex DNA unwinding, DNA recombination, telomere maintenance, telomere maintenance via recombination, DNA unwinding involved in DNA replication, mitochondrial genome maintenance, chromatin remodeling, chromosome organization, chromatin looping, negative regulation of telomere maintenance via telomerase, translesion synthesis, replication fork reversal
GO CC Complete:	replication fork, nucleus, mitochondrial membrane, site of double-strand break, mitochondrion, nuclear replication fork, nucleolus, mitochondrial inner membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=26220\|UniProtKB=Q9H611	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000007166.3\|UniProtKB=K7BQX3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000012347.3\|UniProtKB=G3S8K9	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=2143057\|UniProtKB=Q80SX8	Mus musculus	O
RAT\|RGD=1586053\|UniProtKB=Q1HG60	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007638.5\|UniProtKB=F1MMJ1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000004548.5\|UniProtKB=F1S0B3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000005316.4\|UniProtKB=A0A9L0R620	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011335.6\|UniProtKB=M3WEX7	Felis catus	O
MONDO\|Ensembl=ENSMODG00000010476.4\|UniProtKB=F7ET02	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001139.5\|UniProtKB=F6R806	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022480.1\|UniProtKB=A0A8V0ZR10	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013162.4\|UniProtKB=G1KND2	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000008579.2\|UniProtKB=H2LXB4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-4928\|UniProtKB=Q7ZV90	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000004184.1\|UniProtKB=W5M9F7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000002828.3\|UniProtKB=F6WYU9	Ciona intestinalis	O
CAEEL\|WormBase=WBGene00008695\|UniProtKB=O02243	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00004028\|UniProtKB=G5EFV7	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00029368\|UniProtKB=A8X541	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00027672\|UniProtKB=A8WZ54	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00203407\|UniProtKB=A0A8R1YLI9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0031540\|UniProtKB=Q9VQR3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007775\|UniProtKB=Q7Q395	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_118315\|UniProtKB=E9HVD9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_338047\|UniProtKB=E9I2G8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_247612\|UniProtKB=E9GST4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_253307\|UniProtKB=E9H4I9	Daphnia pulex	O
EREGS\|EnsemblGenome=AGOS_AER128W\|UniProtKB=Q756Y6	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000185430\|UniProtKB=Q59RQ0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A03927g\|UniProtKB=Q6CHW9	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D02607g\|UniProtKB=Q6CAI0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D09669g\|UniProtKB=Q6C9N7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A11539g\|UniProtKB=Q6CH79	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_B12892g\|UniProtKB=Q6CEU3	Yarrowia lipolytica	O
EMENI\|Gene_ORFName=AN6895\|UniProtKB=Q5AXT5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G13370\|UniProtKB=Q4WVU7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07519\|UniProtKB=U9W8Y3	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_00870\|UniProtKB=Q0V544	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU00428\|UniProtKB=Q7RXT1	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_07493\|UniProtKB=A7EQ93	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_03340\|UniProtKB=A7EDF0	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_10457\|UniProtKB=Q0UCQ7	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC887.14c\|UniProtKB=Q9UUA2	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNC04645\|UniProtKB=A0A0S2LIE3	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNH02480\|UniProtKB=Q5KCW7	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNC02830\|UniProtKB=Q5KKJ1	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_02718\|UniProtKB=A0A0D1DZD7	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_06292\|UniProtKB=E3K7N8	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_19486\|UniProtKB=E3LA34	Puccinia graminis	O
ENTH1\|EnsemblGenome=CL6EHI_014050\|UniProtKB=C4LXP4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_192830\|UniProtKB=C4M921	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0293212\|UniProtKB=Q54C21	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0277925\|UniProtKB=Q54Z42	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0268430\|UniProtKB=Q55FJ4	Dictyostelium discoideum	O
LEIMA\|EnsemblGenome=LMJF_11_0320\|UniProtKB=Q4QH48	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.4740\|UniProtKB=Q384Y0	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_11_0330\|UniProtKB=Q4QH47	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.6420\|UniProtKB=Q381V6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.02.4730\|UniProtKB=Q384Y1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_21_1190\|UniProtKB=Q4QC77	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.7240\|UniProtKB=Q38CE9	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_28_2530\|UniProtKB=Q4Q810	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.3660\|UniProtKB=Q383A1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_07_1020\|UniProtKB=Q4QII5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.8.3560\|UniProtKB=Q580X6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.8.700\|UniProtKB=Q57YG0	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_16747\|UniProtKB=A8BBU9	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_172600\|UniProtKB=A2DF11	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_352730\|UniProtKB=A2EG75	Trichomonas vaginalis	O
PHYRM\|Gene=H3GS12_PHYRM\|UniProtKB=H3GS12	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g551550v5\|UniProtKB=A0A2K3D646	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g296150v5\|UniProtKB=A0A2K3DQP7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g485438v5\|UniProtKB=A0A2K3D1R3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g685613v5\|UniProtKB=A0A2K3CW35	Chlamydomonas reinhardtii	O
NELNU\|Gene_ORFName=HUJ06_026511\|UniProtKB=A0A1U8BEI6	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_026512\|UniProtKB=A0A1U8B2Z3	Nelumbo nucifera	O
CAPAN\|EnsemblGenome=T459_23767\|UniProtKB=A0A2G2YTB6	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_20386\|UniProtKB=A0A2G2Z4J0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400017364\|UniProtKB=M1BGL4	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g055900.1\|UniProtKB=A0A3Q7HDF5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107825343\|UniProtKB=A0A1S4D2R7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107787401\|UniProtKB=A0A1S3ZIZ9	Nicotiana tabacum	O
EUCGR\|EnsemblGenome=EUGRSUZ_K01193\|UniProtKB=A0A059A130	Eucalyptus grandis	O
THECC\|EnsemblGenome=TCM_001831\|UniProtKB=A0A061DJT2	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_007G054500v3\|UniProtKB=U5G804	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G085900\|UniProtKB=A0A2C9WC44	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1195020\|UniProtKB=B9S328	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_08G310900\|UniProtKB=K7LA09	Glycine max	O
JUGRE\|EnsemblGenome=Jr10_13650\|UniProtKB=A0A2I4EYT3	Juglans regia	O
PRUPE\|EnsemblGenome=PRUPE_3G170200\|UniProtKB=A0A251Q1C1	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_451566\|UniProtKB=D8SVL5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_451567\|UniProtKB=D8RVZ3	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c19_4830\|UniProtKB=A0A2K1IX83	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c20_2590\|UniProtKB=A0A2K1ITR8	Physcomitrella patens	O
BACTN\|EnsemblGenome=BT_0721\|UniProtKB=Q8A9U4	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_4130\|UniProtKB=Q8A091	Bacteroides thetaiotaomicron	O
THEYD\|EnsemblGenome=THEYE_A0975\|UniProtKB=B5YKP3	Thermodesulfovibrio yellowstonii	O
GEOSL\|EnsemblGenome=GSU0763\|UniProtKB=Q74F46	Geobacter sulfurreducens	O