PANTHER Gene Information

Gene Symbol(s):

purM

Organism:

Escherichia coli

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Gene Name:

Phosphoribosylformylglycinamidine cyclo-ligase

Gene ID:

BAA16387

Protein ID:

P08178

Persistent Id:

PTN001315042

Alternate Ids:

6137340(GI)	M13747(EMBL)
6.3.3.1 {ECO:0000269\|PubMed:3530323}(EC)	PUR5_ECOLI(UniProtKB-ID)
BAA16387(Ensembl)	MetaCyc:AIRS-MON(BioCyc)
AAC75552(EMBL-CDS)	WP_001336050(refSeq)
BAA16387(Ensembl_PRO)	946975(GeneID)
purM(Symbol)	AIRS(Synonym)
BAA16387(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED (PTHR10520)
PANTHER Subfamily:	TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 (PTHR10520:SF12)
PANTHER GO-slim Molecular Function:	ligase activity
PANTHER GO-slim Biological Process:	purine nucleotide biosynthetic process purine nucleobase metabolic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:

Pathway Categories:

De novo purine biosynthesis

Phosphoribosylamine glycine ligase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, phosphoribosylamine-glycine ligase activity, phosphoribosylformylglycinamidine cyclo-ligase activity, ligase activity
GO BP Complete:	adenine biosynthetic process, purine nucleotide biosynthetic process, 'de novo' IMP biosynthetic process
GO CC Complete:	cytoplasm, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
CHLRE\|EnsemblGenome=CHLRE_07g318750v5\|UniProtKB=A8I6R4	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00003p00096050\|UniProtKB=W1NZV7	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_116G00240\|UniProtKB=A0A0K9Q1Y5	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_101G00140\|UniProtKB=A0A0K9Q6E7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g23720\|UniProtKB=A0A804LB94	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_022341mg\|UniProtKB=K3Z721	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G012300\|UniProtKB=C5YYH7	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3009G072000\|UniProtKB=C5YUD2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb115440\|UniProtKB=A0A804MVU9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb284260\|UniProtKB=C4JA40	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0831500\|UniProtKB=Q850Z8	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g02990v3\|UniProtKB=I1GLA9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0433410\|UniProtKB=A0A8I6Y5K6	Hordeum vulgare subsp. vulgare	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0433430\|UniProtKB=A0A8I7BDR1	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5D02G068900\|UniProtKB=A0A3B6MMJ0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G059100\|UniProtKB=A0A3B6LGE7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G057700\|UniProtKB=A0A3B6KBR3	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0528920\|UniProtKB=F2CZA8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G509100\|UniProtKB=A0A3B6LXB6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G364400\|UniProtKB=A0A3B6I1J0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G509100\|UniProtKB=A0A3B6N1I9	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_008846\|UniProtKB=A0A1U7ZXX0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110799187\|UniProtKB=A0A9R0K6B3	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0253691\|UniProtKB=A0A251UI09	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0787761\|UniProtKB=A0A251RMN8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800400550\|UniProtKB=A0A9R1WZU7	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C300113120\|UniProtKB=A0A9R1W523	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007595mg\|UniProtKB=A0A022PUE2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_00494\|UniProtKB=A0A1U8G9K5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400027622\|UniProtKB=M1CN35	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400023032\|UniProtKB=M1C421	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc04g058090.3\|UniProtKB=A0A3Q7G5K0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107764177\|UniProtKB=A0A1S3XE96	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107798458\|UniProtKB=A0A1S4AJS4	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_14s0108g00730\|UniProtKB=F6H5T1	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi07g00389\|UniProtKB=D7U2F7	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_L02454\|UniProtKB=A0A058ZQS2	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_A02767\|UniProtKB=A0A059DJU0	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00124518001\|UniProtKB=A0A078F385	Brassica napus	O
BRACM\|EnsemblGenome=Bra003204\|UniProtKB=M4CG71	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00003468001\|UniProtKB=A0A078IN80	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra007126\|UniProtKB=M4CSD4	Brassica campestris	LDO
ARATH\|TAIR=locus=2097203\|UniProtKB=Q05728	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107924705\|UniProtKB=A0A1U8LBJ9	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107912339\|UniProtKB=A0A1U8K4Q8	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_004771\|UniProtKB=A0A061DT32	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g046037mg\|UniProtKB=A0A067DJ64	Citrus sinensis	LDO
CITSI\|Gene_ORFName=CISIN_1g016548mg\|UniProtKB=A0A067ET69	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_014G123000v3\|UniProtKB=B9I9L4	Populus trichocarpa	O
POPTR\|Gene_ORFName=POPTR_002G198600\|UniProtKB=A0A3N7ESQ9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_05G001800\|UniProtKB=A0A2C9VS34	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G225900\|UniProtKB=A0A2C9WQU8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1347740\|UniProtKB=B9RNH2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G001000\|UniProtKB=I1KNV7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G192900\|UniProtKB=I1K506	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g093860\|UniProtKB=B7FJ14	Medicago truncatula	LDO
MEDTR\|EnsemblGenome=MTR_5g093890\|UniProtKB=G7K8Q2	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_15640\|UniProtKB=A0A2I4DDF4	Juglans regia	O
JUGRE\|Gene=LOC108979048\|UniProtKB=A0A2I4DDE3	Juglans regia	O
JUGRE\|EnsemblGenome=Jr14_18150\|UniProtKB=A0A6P9E072	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G148580\|UniProtKB=A0A0A0KNN8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G528600\|UniProtKB=M5XEV5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_422140\|UniProtKB=D8SHG8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_234696\|UniProtKB=D8SP76	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_117177\|UniProtKB=D8SHG9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_132606\|UniProtKB=D8T5R3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_92321\|UniProtKB=D8RFS4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c6_25750\|UniProtKB=A0A2K1KH55	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c5_3030\|UniProtKB=A0A2K1KI88	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0003s0273\|UniProtKB=A0A2R6XTN5	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_006400030\|UniProtKB=A0A1Y1IPA4	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0582\|UniProtKB=A9A265	Nitrosopumilus maritimus	LDO
SACS2\|EnsemblGenome=SSO0636\|UniProtKB=Q9UX29	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE0221\|UniProtKB=Q8ZZK0	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_0130\|UniProtKB=Q8TUD7	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0203\|UniProtKB=Q57656	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_0876G\|UniProtKB=Q9HR39	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK0208\|UniProtKB=Q5JFN7	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_1262\|UniProtKB=A9WK39	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO4087\|UniProtKB=Q7AKK2	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv0809\|UniProtKB=I6Y4V6	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO2875\|UniProtKB=A5I5W1	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr0048\|UniProtKB=Q8DRM4	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01015\|UniProtKB=Q2FZI8	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99845\|UniProtKB=Q8Y6C3	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_06500\|UniProtKB=P12043	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_0331\|UniProtKB=Q81IQ1	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1251\|UniProtKB=Q9X0X8	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1394\|UniProtKB=Q9RUJ2	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC88661\|UniProtKB=Q7NMP5	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10521\|UniProtKB=Q55422	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_2935\|UniProtKB=Q8F242	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_4211\|UniProtKB=Q8A010	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB12745\|UniProtKB=Q7UI59	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_769\|UniProtKB=O66968	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0887\|UniProtKB=B5YKG0	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1418\|UniProtKB=B8E0V5	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN0986\|UniProtKB=Q8REV3	Fusobacterium nucleatum	LDO
NEIMB\|EnsemblGenome=NMB1252\|UniProtKB=Q9JZ80	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU1758\|UniProtKB=Q74CB6	Geobacter sulfurreducens	LDO
COXBU\|EnsemblGenome=CBU_1736\|UniProtKB=Q83AZ0	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_1429\|UniProtKB=P43848	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_2760\|UniProtKB=Q8EDI8	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2226\|UniProtKB=Q9KPY6	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC2789\|UniProtKB=Q8P725	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA0945\|UniProtKB=Q9I513	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2499\|UniProtKB=P74883	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_2696\|UniProtKB=Q8ZCX8	Yersinia pestis	LDO