PANTHER Gene Information   
Gene Symbol(s): Fer
Organism: Rattus norvegicus
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Gene Name: Tyrosine-protein kinase Fer
Gene ID: 1306273
Protein ID: P09760
Persistent Id: PTN000700812
Alternate Ids:
CHEMBL4523172(ChEMBL) 56170(GI)
2.7.10.2(EC) 1306273(RGD)
Fert2(Synonym) XM_008767367(refSeq)
F1MA12(AltAccession) ENSRNOG00000015898(Ensembl)
ENSRNOP00000090379(Ensembl_PRO) FER_RAT(UniProtKB-ID)
Fer(Symbol) 301737(GeneID)
CAA31778(EMBL-CDS) X13412(EMBL)
ENSRNOT00000097737(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: TYROSINE-PROTEIN KINASE (PTHR24418)
PANTHER Subfamily: TYROSINE-PROTEIN KINASE FER (PTHR24418:SF227)  
PANTHER GO-slim Molecular Function: protein tyrosine kinase activity
PANTHER GO-slim Biological Process: immune response-regulating cell surface receptor signaling pathway
chemotaxis
cell adhesion
PANTHER GO-slim Cellular Component:
PANTHER protein class: non-receptor tyrosine protein kinase
Pathway Categories: Cadherin signaling pathway
   FPS/FES-related tyrosine kinase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, protein tyrosine kinase activity, non-membrane spanning protein tyrosine kinase activity, histone H2AXY142 kinase activity, epidermal growth factor receptor binding, protein kinase activity, protein phosphatase 1 binding, lipid binding, histone H3Y41 kinase activity
GO BP Complete: peptidyl-tyrosine phosphorylation, adherens junction disassembly, male gonad development, insulin receptor signaling pathway, positive regulation of cell population proliferation, Fc-epsilon receptor signaling pathway, protein autophosphorylation, Sertoli cell development, cell adhesion, regulation of epidermal growth factor receptor signaling pathway, protein phosphorylation, positive regulation of NF-kappaB transcription factor activity, chemotaxis, chromatin remodeling, seminiferous tubule development, cytokine-mediated signaling pathway, substrate adhesion-dependent cell spreading, interleukin-6-mediated signaling pathway, cellular response to macrophage colony-stimulating factor stimulus, Kit signaling pathway, germ cell development, tyrosine phosphorylation of STAT protein, regulation of lamellipodium assembly, signal transduction, diapedesis, platelet-derived growth factor receptor signaling pathway, microtubule cytoskeleton organization, regulation of protein phosphorylation, cell-cell adhesion mediated by cadherin, positive regulation of actin filament polymerization, extracellular matrix-cell signaling, response to platelet-derived growth factor, response to lipopolysaccharide, adherens junction assembly, actin cytoskeleton organization, cellular response to reactive oxygen species, negative regulation of mast cell activation involved in immune response, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, regulation of fibroblast migration, positive regulation of cell migration
GO CC Complete: microtubule cytoskeleton, chromatin, plasma membrane, cytoplasmic side of plasma membrane, nucleus, adherens junction, cytoskeleton, cytoplasm, cell cortex, actin cytoskeleton, cytosol, cell junction, protein-containing complex, lamellipodium
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by SCF-KIT, Signaling by Receptor Tyrosine Kinases, Signal Transduction

Orthologs