PANTHER Gene Information

Gene Symbol(s):

gyrA

Organism:

Escherichia coli

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Gene Name:

DNA gyrase subunit A

Gene ID:

BAA16048

Protein ID:

P0AES4

Persistent Id:

PTN000018884

Alternate Ids:

BAA16048(Ensembl_TRS)	CAA29919(EMBL-CDS)
16130166(GI)	5.6.2.2 {ECO:0000255\|HAMAP-Rule:MF_01897, ECO:0000269\|PubMed:12051842, ECO:0000269\|PubMed:18642932, ECO:0000269\|PubMed:186775, ECO:0000269\|PubMed:19965760, ECO:0000269\|PubMed:9278055}(EC)
BAA16048(Ensembl)	U00096(EMBL)
P09097(AltAccession)	GYRA_ECOLI(UniProtKB-ID)
EcoCyc:EG10423-MON(BioCyc)	NP_416734(refSeq)
gyrA{ECO:0000255\|HAMAP-Rule:MF_01897}(Symbol)	nalA{ECO:0000303\|PubMed:337300}(Synonym)
AAC75291(Ensembl_PRO)	CHEMBL1858(ChEMBL)
75206476(GeneID)
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PANTHER Classification

PANTHER Family:	DNA GYRASE/TOPOISOMERASE SUBUNIT A (PTHR43493)
PANTHER Subfamily:	DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL (PTHR43493:SF5)
PANTHER GO-slim Molecular Function:	ATP binding isomerase activity ATP-dependent activity, acting on DNA DNA binding
PANTHER GO-slim Biological Process:	DNA conformation change DNA metabolic process
PANTHER GO-slim Cellular Component:	catalytic complex
PANTHER protein class:	DNA topoisomerase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, ATP binding, ATP-dependent activity, acting on DNA, identical protein binding, protein binding, DNA topoisomerase activity, DNA negative supercoiling activity, DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO BP Complete:	DNA-templated transcription, chromosome organization, DNA-templated DNA replication, response to antibiotic, DNA topological change, response to xenobiotic stimulus, negative regulation of DNA-templated DNA replication
GO CC Complete:	cytoplasm, DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex, membrane, cytosol, chromosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
DAPPU\|EnsemblGenome=DAPPUDRAFT_340581\|UniProtKB=E9I4E7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_314641\|UniProtKB=E9G6Z8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_338889\|UniProtKB=E9I347	Daphnia pulex	LDO
PLAF7\|EnsemblGenome=PF3D7_1223300\|UniProtKB=Q8I0X3	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_39845\|UniProtKB=B8BXG7	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_04g221650v5\|UniProtKB=A0A2K3DUA4	Chlamydomonas reinhardtii	LDO
HALSA\|EnsemblGenome=VNG_0889G\|UniProtKB=Q9HR29	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_1241\|UniProtKB=A9WK19	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO5836\|UniProtKB=O50510	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO3873\|UniProtKB=P35885	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv0006\|UniProtKB=P9WG47	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_204\|UniProtKB=P47446	mycoplasma genitalium	O
STRR6\|EnsemblGenome=spr0757\|UniProtKB=Q8DQB4	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01352\|UniProtKB=Q2FYS4	Staphylococcus aureus	O
LISMO\|Gene=parC\|UniProtKB=Q8Y7J0	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_18100\|UniProtKB=Q45066	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3596\|UniProtKB=Q81AH2	Bacillus cereus	O
MYCGE\|EnsemblGenome=MG_004\|UniProtKB=P47250	mycoplasma genitalium	LDO
CLOBH\|Gene_OrderedLocusName=CBO2769\|UniProtKB=A5I5K5	Clostridium botulinum	O
CLOBH\|Gene_OrderedLocusName=CBO0007\|UniProtKB=A5HXQ3	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1099\|UniProtKB=Q8DPM2	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_00006\|UniProtKB=Q2G2Q0	Staphylococcus aureus	LDO
LISMO\|Gene=gyrA\|UniProtKB=Q8YAV6	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_00070\|UniProtKB=P05653	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_0006\|UniProtKB=Q81JD0	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1084\|UniProtKB=O33926	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1913\|UniProtKB=Q9RT53	Deinococcus radiodurans	LDO
GLOVI\|Gene=gyrA\|UniProtKB=Q7NIY2	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA17102\|UniProtKB=P73077	Synechocystis	O
SYNY3\|EnsemblGenome=BAA10380\|UniProtKB=Q55738	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_4193\|UniProtKB=Q8EYM0	Leptospira interrogans	O
LEPIN\|EnsemblGenome=LA_0006\|UniProtKB=Q8CM44	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_3579\|UniProtKB=Q8A1S9	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_0899\|UniProtKB=Q8A9B6	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_189\|UniProtKB=O84192	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB3465\|UniProtKB=Q7UU73	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB8841\|UniProtKB=Q7UMG7	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_980\|UniProtKB=O67108	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0041\|UniProtKB=B5YGW5	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1263\|UniProtKB=B8E096	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN2125\|UniProtKB=Q8RHB2	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0701\|UniProtKB=P48370	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB1384\|UniProtKB=Q9JYX5	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU0004\|UniProtKB=Q74H88	Geobacter sulfurreducens	LDO
BRADU\|Gene=gyrA\|UniProtKB=Q89L52	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0524\|UniProtKB=Q83E13	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_1264\|UniProtKB=P43700	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_2411\|UniProtKB=Q8EEH1	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_1258\|UniProtKB=Q9KSJ8	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC1574\|UniProtKB=Q8PAB1	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3168\|UniProtKB=P48372	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2272\|UniProtKB=P37411	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO1216\|UniProtKB=A0A380PMQ0	Yersinia pestis	LDO