PANTHER Gene Information

Gene Symbol(s):

GABRA2

Organism:

Bos taurus

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Gene Name:

Gamma-aminobutyric acid receptor subunit alpha-2

Gene ID:

GABRA2

Protein ID:

P10063

Persistent Id:

PTN001825185

Alternate Ids:

NP_776966(refSeq)	120756(GI)
X12361(EMBL)	GBRA2_BOVIN(UniProtKB-ID)
CAA30924(EMBL-CDS)	282236(GeneID)
GBRA2(Synonym)	GABRA2(Symbol)
CHEMBL2094107(ChEMBL)
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PANTHER Classification

PANTHER Family:	NEUROTRANSMITTER GATED ION CHANNEL (PTHR18945)
PANTHER Subfamily:	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-2 (PTHR18945:SF218)
PANTHER GO-slim Molecular Function:	neurotransmitter receptor activity transmembrane signaling receptor activity chloride channel activity extracellular ligand-gated monoatomic ion channel activity
PANTHER GO-slim Biological Process:	regulation of postsynaptic membrane potential synapse assembly chemical synaptic transmission chloride transmembrane transport
PANTHER GO-slim Cellular Component:	leading edge membrane receptor complex postsynapse dendrite cell projection membrane
PANTHER protein class:	ligand-gated ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	GABA-A receptor activity, chloride channel activity, benzodiazepine receptor activity, GABA-gated chloride ion channel activity
GO BP Complete:	regulation of postsynaptic membrane potential, chloride transmembrane transport, inhibitory synapse assembly, synaptic transmission, GABAergic, gamma-aminobutyric acid signaling pathway
GO CC Complete:	chloride channel complex, dendrite membrane, cytoplasmic vesicle membrane, postsynapse, postsynaptic membrane, GABA-A receptor complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4076\|UniProtKB=P47869	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016026.6\|UniProtKB=H2QPE5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000006837.3\|UniProtKB=G3QVC6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003614.4\|UniProtKB=G7MSU6	Macaca mulatta	O
MOUSE\|MGI=MGI=95614\|UniProtKB=P26048	Mus musculus	O
RAT\|RGD=61856\|UniProtKB=P23576	Rattus norvegicus	O
PIG\|Ensembl=ENSSSCG00005007084.1\|UniProtKB=A0A4X1ULV0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000000924.4\|UniProtKB=F6U3M0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027986.4\|UniProtKB=A0A337SQD9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015709.1\|UniProtKB=A0A8I3S1N5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000020598.4\|UniProtKB=F6ZBY7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000036930.1\|UniProtKB=A0A6I8NSL3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010014303.1\|UniProtKB=A0A8V0YH87	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006901.3\|UniProtKB=G1KG07	Anolis carolinensis	O
XENLA\|Gene=gabra2.L\|UniProtKB=A0A8J0TIN4	Xenopus laevis	O
XENLA\|Gene=gabra2.S\|UniProtKB=Q6AX36	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1000398\|UniProtKB=F7DCL6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009490.2\|UniProtKB=H2M0H7	Oryzias latipes	O
DANRE\|Gene=LOC100001259\|UniProtKB=A0A8M9PZF4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-141216-16\|UniProtKB=E7F635	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012384.1\|UniProtKB=W5N3N9	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000004249.3\|UniProtKB=F6YG13	Ciona intestinalis	O
BRAFL\|Gene=LOC118405170\|UniProtKB=A0A9J7HLD7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419656\|UniProtKB=A0A9J7LFX6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115922390\|UniProtKB=A0A7M7NIN7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891919\|UniProtKB=A0A7M7NGH4	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00008551\|UniProtKB=Q6BET0	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041559\|UniProtKB=A8Y4K8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00102482\|UniProtKB=A0A2A6BZY3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00013914\|UniProtKB=G5ECN1	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG15739\|UniProtKB=A8XMN8	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0030707\|UniProtKB=Q9VXL9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000039\|UniProtKB=A0A1S4G7Y0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008334\|UniProtKB=D2A157	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_190742\|UniProtKB=E9FTL3	Daphnia pulex	O
DROME\|FlyBase=FBgn0001134\|UniProtKB=Q24352	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011349\|UniProtKB=A0A1S4H6E8	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008266\|UniProtKB=A8DMU2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_40350\|UniProtKB=E9FSP0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021474\|UniProtKB=B7Q4M8	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g22284\|UniProtKB=A7S763	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_24218\|UniProtKB=A9UVR7	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_39352\|UniProtKB=A9VE08	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_30738\|UniProtKB=A9UNW8	Monosiga brevicollis	O
CHLRE\|EnsemblGenome=CHLRE_17g706200v5\|UniProtKB=A0A2K3CP94	Chlamydomonas reinhardtii	O