The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

GLRX

Organism:

Sus scrofa

View Gene in Tree

Tree

Gene Name:

Glutaredoxin-1

Gene ID:

ENSSSCG00000039731

Protein ID:

P12309

Persistent Id:

PTN001606808

Alternate Ids:

397463(GeneID)	NP_999398(refSeq)
GRX(Synonym)	ENSSSCP00055013744(Ensembl_PRO)
ENSSSCT00050100287(Ensembl_TRS)	GLRX(Symbol)
M31453(EMBL)	AAA31132(EMBL-CDS)
157831627(GI)	ENSSSCG00030008733(Ensembl)
GLRX1_PIG(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	GLUTAREDOXIN-1 (PTHR46185)
PANTHER Subfamily:	GLUTAREDOXIN-1 (PTHR46185:SF1)
PANTHER GO-slim Molecular Function:	disulfide oxidoreductase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	oxidoreductase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	glutathione disulfide oxidoreductase activity
GO BP Complete:	-
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, Metabolism of nucleotides, Interconversion of nucleotide di- and triphosphates

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4330\|UniProtKB=P35754	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000048162.1\|UniProtKB=A0A2I3TL57	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000044246.1\|UniProtKB=H2QR90	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000037801.1\|UniProtKB=A0A2I2ZM88	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000009175.3\|UniProtKB=G3R1A5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005312.4\|UniProtKB=F7GJV9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2135625\|UniProtKB=Q9QUH0	Mus musculus	LDO
RAT\|RGD=7600849\|UniProtKB=Q6AY00	Rattus norvegicus	O
RAT\|RGD=150341704\|UniProtKB=A0A8I5ZRA0	Rattus norvegicus	O
RAT\|RGD=70951\|UniProtKB=Q9ESH6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038186\|UniProtKB=P10575	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000030454.3\|UniProtKB=E1BKQ7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000031256.4\|UniProtKB=E1B773	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054293.1\|UniProtKB=A0A3Q1LQQ0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000033604.4\|UniProtKB=F1MIJ5	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000038238.3\|UniProtKB=G8JKV3	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000024613.4\|UniProtKB=A0A5F5PPQ9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000046772.1\|UniProtKB=A0A337SVX3	Felis catus	O
FELCA\|Ensembl=ENSFCAG00000027572.4\|UniProtKB=M3X3M9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013738.1\|UniProtKB=A0A8I3NFC4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000045828.1\|UniProtKB=A0A5F8HC20	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000048801.1\|UniProtKB=A0A6I8NRB4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012918.1\|UniProtKB=A0A8V0YB63	Gallus gallus	LDO
CHICK\|Gene=GLRX\|UniProtKB=P79764	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000012936.4\|UniProtKB=G1KMZ3	Anolis carolinensis	LDO
XENLA\|Gene=glrx.S\|UniProtKB=A0A1L8HR55	Xenopus laevis	O
XENLA\|Gene=glrx.L\|UniProtKB=Q6P7J6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-971624\|UniProtKB=Q28I60	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000026613.1\|UniProtKB=A0A3B3I7Q1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041010-11\|UniProtKB=Q5XJ42	Danio rerio	LDO
STRPU\|EnsemblGenome=LOC582331\|UniProtKB=A0A7M7RC15	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00021331\|UniProtKB=Q9N456	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00040679\|UniProtKB=A8Y1E0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00306064\|UniProtKB=A0A8R1V689	Pristionchus pacificus	LDO
PLAF7\|EnsemblGenome=PF3D7_0306300\|UniProtKB=Q9NLB2	Plasmodium falciparum	LDO