Gene Symbol(s):
|
Gpc3
|
Organism: |
Rattus norvegicus |
View Gene in Tree |
|
Gene Name: |
Glypican-3
|
Gene ID: |
2725
|
Protein ID: |
P13265
|
Persistent Id: |
PTN000850525 |
Alternate Ids: |
Gpc3(Symbol) |
2725(RGD) |
BC085756(EMBL) |
55249689(GI) |
AAH85756(EMBL-CDS) |
GPC3(Synonym) |
NM_012774(refSeq) |
Q5U326(AltAccession) |
25236(GeneID) |
GPC3_RAT(UniProtKB-ID) |
Show All
|
|
Pathway Categories: |
No pathway information available
|
GO MF Complete: |
peptidyl-dipeptidase inhibitor activity
|
GO BP Complete: |
negative regulation of growth, negative regulation of cell population proliferation, positive regulation of endocytosis, anterior/posterior axis specification, epithelial cell proliferation, kidney development, regulation of canonical Wnt signaling pathway, canonical Wnt signaling pathway, Wnt signaling pathway, planar cell polarity pathway, cell proliferation involved in metanephros development, cell migration, embryonic hindlimb morphogenesis, lung development, regulation of protein localization to membrane, regulation of non-canonical Wnt signaling pathway, biological_process, bone mineralization, positive regulation of Wnt signaling pathway, planar cell polarity pathway, body morphogenesis, coronary vasculature development, positive regulation of canonical Wnt signaling pathway, smoothened signaling pathway, positive regulation of protein catabolic process, positive regulation of D-glucose import, regulation of growth, negative regulation of smoothened signaling pathway, animal organ morphogenesis, mesonephric duct morphogenesis, osteoclast differentiation, negative regulation of canonical Wnt signaling pathway, positive regulation of BMP signaling pathway, response to bacterium, cell migration involved in gastrulation, branching involved in ureteric bud morphogenesis, positive regulation of smoothened signaling pathway, negative regulation of epithelial cell proliferation, cell proliferation involved in kidney development, mesenchymal cell proliferation involved in ureteric bud development
|
GO CC Complete: |
side of membrane, collagen-containing extracellular matrix, plasma membrane, lysosome, cell surface
|
Reactome Pathways: |
A tetrasaccharide linker sequence is required for GAG synthesis, Glycosaminoglycan metabolism, Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), Metabolism of carbohydrates, Retinoid metabolism and transport, Metabolism of proteins, Post-translational protein modification, Heparan sulfate/heparin (HS-GAG) metabolism, Visual phototransduction, Metabolism, HS-GAG biosynthesis, Post-translational protein phosphorylation, Chondroitin sulfate/dermatan sulfate metabolism, Metabolism of vitamins and cofactors, HS-GAG degradation, Sensory Perception, Metabolism of fat-soluble vitamins
|
|