PANTHER Gene Information   
Gene Symbol(s): H2-D1
Organism: Mus musculus
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Gene Name: H-2 class I histocompatibility antigen, D-P alpha chain
Gene ID: MGI:95896
Protein ID: P14427
Persistent Id: PTN000422680
Alternate Ids:
H-2D(P)(Synonym) 387454(GI)
AAA39603(EMBL-CDS) H2-D1(Symbol)
HA14_MOUSE(UniProtKB-ID) M12381(EMBL)
MGI:95896(MGI)
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PANTHER Classification
PANTHER Family: MHC CLASS I-RELATED (PTHR16675)
PANTHER Subfamily: HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN (PTHR16675:SF251)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: regulation of lymphocyte mediated immunity
immune response
positive regulation of cellular process
positive regulation of adaptive immune response
antigen processing and presentation
regulation of leukocyte mediated cytotoxicity
PANTHER GO-slim Cellular Component: external side of plasma membrane
extracellular space
PANTHER protein class: major histocompatibility complex protein
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, peptide antigen binding, protein homodimerization activity, T cell receptor binding, peptide binding, MHC class I protein binding, natural killer cell lectin-like receptor binding, TAP1 binding, signaling receptor binding, CD8 receptor binding, TAP2 binding, protein-containing complex binding, TAP binding, protein binding, protein-folding chaperone binding, TAP complex binding, beta-2-microglobulin binding, 14-3-3 protein binding
GO BP Complete: immune response, negative regulation of neuron projection development, T cell mediated cytotoxicity, positive regulation of T cell mediated cytotoxicity, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO CC Complete: MHC class I peptide loading complex, external side of plasma membrane, Golgi membrane, endoplasmic reticulum, Golgi apparatus, lysosomal membrane, plasma membrane, Golgi medial cisterna, cell surface, MHC class I protein complex, early endosome membrane, lumenal side of endoplasmic reticulum membrane, extracellular space, early endosome, membrane raft, phagocytic vesicle membrane, endoplasmic reticulum exit site, MHC class Ib protein complex, cis-Golgi network membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, ER-Phagosome pathway, Innate Immune System, Neutrophil degranulation, Class I MHC mediated antigen processing & presentation, Antigen processing-Cross presentation, Adaptive Immune System, DAP12 interactions, Antigen Presentation: Folding, assembly and peptide loading of class I MHC, Endosomal/Vacuolar pathway

Orthologs